Antimelanogenic effects of <Emphasis Type="Italic">Inula britannica</Emphasis> flower petal extract fermented by <Emphasis Type="Italic">Lactobacillus plantarum</Emphasis> KCCM 11613P

The inhibitory effects of Lactobacillus plantarum-fermented and non-fermented Inula britannica extracts on the tyrosinase activity were comparatively investigated to examine whether and how they improve the whitening activity, and the contents of total flavonoids and polyphenolics as bioactive compounds were determined. The skin whitening activity using in vitro or ex vivo tyrosinase and L-3,4-dihydroxyphenylalanine (L-DOPA) staining was examined. The total flavonoid content (TFC) was increased by 13.4% after 72 h-fermentation. The viabilities of the B16F10 cells treated with the fermented and non-fermented control extracts were 100.26% and 92.15% at 500 μg/ml, respectively. In addition, the inhibition of tyrosinase activity was increased by the fermented samples from 29.33% to 41.74% following fermentation for up to 72 h. The tyrosinase activity of the untreated control group was increased to 145.69% in B16F10 cells. The results showed that I. britannica fermented by L. plantarum dose-dependently inhibited tyrosinase activity, which was stimulated by α-melanocyte stimulating hormone. These results suggest that lactic fermented I. britannica extracts can be used as effective skin-whitening materials.     

The Intellectual Structure of Research on Educational Technology in Science Education (ETiSE): A Co-citation Network Analysis of Publications in Selected Journals (2008–2013)

The main purpose of this paper is to investigate the intellectual structure of the research on educational technology in science education (ETiSE) within the most recent years (2008–2013). Based on the criteria for educational technology research and the citation threshold for educational co-citation analysis, a total of 137 relevant ETiSE papers were identified from the International Journal of Science Education, the Journal of Research in Science Teaching, Science Education, and the Journal of Science Education and Technology. Then, a series of methodologies were performed to analyze all 137 source documents, including document co-citation analysis, social network analysis, and exploratory factor analysis. As a result, 454 co-citation ties were obtained and then graphically visualized with an undirected network, presenting a global structure of the current ETiSE research network. In addition, four major underlying intellectual subfields within the main component of the ETiSE network were extracted and named as: (1) technology-enhanced science inquiry, (2) simulation and visualization for understanding, (3) technology-enhanced chemistry learning, and (4) game-based science learning. The most influential co-citation pairs and cross-boundary phenomena were then analyzed and visualized in a co-citation network. This is the very first attempt to illuminate the core ideas underlying ETiSE research by integrating the co-citation method, factor analysis, and the networking visualization technique. The findings of this study provide a platform for scholarly discussion of the dissemination and research trends within the current ETiSE literature.     

Toddlers' Attachment Security to Child-Care Providers: The Safe and Secure Scale

Attachment relationships of toddlers (N = 45) to their child-care providers were investigated. Children's behaviors with their mothers were observed at home at 24 months and with their child-care providers at 26 months. Attachment Q-Sort procedures were used at home (90 items) and in child care (78 items); the latter yielded a 15-item Safe and Secure Scale describing the safe haven and secure base functions of attachment relationships in child care—being able to (a) seek and receive positive attention, (b) feel safe and protected, (c) receive support for exploration, (d) receive consolation when distressed, and (e) seek and accept assistance. Independent observational measures of child-care quality also were obtained at 24 months. As hypothesized, the Safe and Secure Scale was related to proximal rather than distal indicators of child-care quality, and it was a stronger measure than the child-caregiver Q-security score that was based on all 78 items. Child-mother and child-caregiver security were significantly related.     

Careers guidance services in a changing Europe

Current initiatives designed to develop stronger international co-operation between guidance services within the European Community are outlined. The implications of extending the Community to cover other European countries are discussed. The issue is raised of whether a common European approach to guidance is likely to emerge, and whether it is likely to differ from American approaches. Adapted and updated version of a paper presented at the International Conference of the International Association for Educational and Vocational Guidance held at the University of Lisbon, Portugal, on 9–13 September 1991.     

Visualization of structured packing with laser induced fluorescence technique: Two-dimensional measurement of liquid concentration distribution

A method of using laser induced fluorescence(LIF)technique was applied to two-dimensional measurement of the liquid concentration distribution in the 250Y structured packing sheet. The experimental structured packing sheet was made of perspex so that the laser could pass through it. The visualization of the distribution of the liquid concentration in the structured packing sheet was realized. The calibration of the thickness and liquid concentration was carried out firstly and the regression formula I=kcd was acquired, in which concentration c and the liquid film thickness d were both considered. Then the liquid feed of uniform tracer(rhodamine)concentration entered the perspex structured packing from the top under different spraying densities. The corresponding thickness of liquid film on the packing was calculated. Finally, tracer(rhodamine)with a high concentration was injected only at one fixed point of the structured packing under different spraying densities of the liquid. With the known liquid film thickness, the concentration distribution of the tracer can be calculated inside the structured packing sheet.     

Post-secondary Science Students’ Explanations of <Emphasis Type="Italic">Randomness</Emphasis> and <Emphasis Type="Italic">Variation</Emphasis> and Implications for Science Learning

The concepts of randomness and variation are pervasive in science. The purpose of this study was to document how post-secondary life science students explain randomness and variation, infer relationships between their explanations, and ability to describe and identify appropriate and inappropriate variation, and determine if students can identify sources of variation. An instrument designed to test statistical concepts was administered to 282 college students from three universities, ranging from introductory non-science majors to science graduate students. Students readily distinguished between causes of variation. A naïve no-pattern concept of randomness persisted from first-year non-science majors to senior-level science majors, contributing to incorrect responses on the variation instrument. Students’ expressions of randomness were better predictors of performance on the variation instrument than their expressions of variation. It is argued that inclusion of everyday language uses of randomness in instruction can bridge the gap between vernacular and scientific uses of this term.     

基于直接寻找法的电阻抗断层成像

Solution to impedance distribution in electrical impedance tomography （EIT） is an ill-posed nonlinear inverse problem. It is especially difficult to reconstruct an EIT image in the center area of a measured object. Tikhonov regularization with some prior information is a sound regnlarization method for static electrical impedance tomography under the condition that some true impedance distribution information is known a priori. This paper presents a direct search method （DSM） as pretreatment of image reconstruction through which one not only can construct a regularization matrix which may locate in areas of impedance change, but also can obtain an initial impedance distribution more similar to the true impedance distribution, as well as better current modes which can better distinguish the initial distribution and the true distribution. Simulation results indicate that, by using DSM, resolution in the center area of the measured object can be improved significantly.