Mental toughness and transitions to high school and to undergraduate study

Mental toughness can be conceptualised as a set of attributes that allow people to deal effectively with challenges, stressors and pressure. Recent work has suggested that it may be a valuable construct to consider within educational settings. The current studies explored the associations between mental toughness and educational transitions. Study 1 examined the relationships between mental toughness and concerns about moving to a new school in 105 children aged 12–13 years of age. The results revealed significant relationships between several aspects of mental toughness, but particularly confidence in abilities, and children’s concerns. Study 2 examined the relationships between mental toughness and adjustment to university in 200 undergraduate students at various stages of their course. The results revealed a role for several aspects of mental toughness; commitment, control of life, control of emotion, confidence in abilities and interpersonal confidence. The results are discussed in terms of implications for educational practice. It is suggested that measures of mental toughness could be used to identify individuals who may benefit from additional support during transition to a new school or to university, and that future research should explore the potential benefits of mental toughness training.     

Intuitive statistical inference: How pigeons categorize binomial samples

Pigeons categorized binomial samples produced by two complementary random processes. Samples were 1, 2, 4, or 8 successively presented outcomes (vertical or horizontal lines) of, in effect, tossing one of two equally likely coins. One coin (A) was biased in favor of vertical, and the other coin (B) was similarly biased in favor of horizontal. Choosing red or green stimuli presented after each sample was reinforced with food if coin A or coin B had been tossed, respectively. In that sense, choosing red or green was logically analogous to inferring that the statistical evidence reflected tossing of coin A or coin B, respectively. The statistical diagnosticity of a sample, the relative likelihood of its having been produced by a particular coin, equaled, except for sampling fluctuation, the relative frequency of reinforcement of a particular color given that sample, and was experimentally varied by the bias on the coins and by sample size. All the variables that affect optimal, formal inference about binomial samples also affected intuitive inference. But inferences were very suboptimal: “undermatching” was obtained in part due to control of categorization by the sequential structure of binomial samples. These results reveal limitations of optimality theories for animal decision making in the face of uncertainty when observations in samples are presented successively. On the other hand, they are generally compatible with molecular analyses of instrumental learning which assign an important role to the local temporal organization of events preceding reinforcement. Most generally, they show that maladaptive control over intuitive statistical inference by a variable upon which optimal performance does not depend is neither a uniquely human phenomenon nor dependent upon linguistic strategies.     

Method evaluation of an enzymatic method for serum creatinine

Selecting the correct method for routine analysis by ‘method evaluation’ is an important component of quality assurance. It is a step-wise procedure that evaluates various analytical parameters like accuracy, precision etc of the given method. Finally reference intervals are established for selected population. We evaluated an enzymatic method for serum creatinine. The results show that it is an acceptable method based on the above mentioned criteria.     

Serum super oxide dismutase (SOD), malondialdehyde (MDA) levels in urinary disorders

Evaluation of serum SOD and MDA level was done in 21 first episode renal stone formers, 9 recurrent stone formers, 20 patients with obstructive uropathy other than urolithiasis and 12 patients with urinary infection. Twenty-two healthy volunteers were taken as controls. The level of SOD in respective groups was 2.12±0.84, 2.78±0.85, 1.42±0.31, 1.98±0.70 and 2.32±0.62 units/ml and of MDA was 2.61±1.07, 2.69±1.15, 1.65±0.33, 1.33±0.34 and 1.55±0.48 n mol/ml respectively. The results indicate increased peroxidative stressin nephrolithiasis only. Since SOD level was normal in all groups, this increased peroxidative stress in nephrolithiasis should be due to factors other than this one.     

Clinical usefulness of alterations in sialic acid,sialyl transferase and sialoproteins in breast cancer

Sialic acid, the end moieties of the carbohydrate chains are biologically important and essential for functions of glycoconjugates and are reported to be altered in cancer patients. Two hundred and twenty five breast cancer (BC) patients, 100 patients with benign breast disease (BBD) and 100 healthy females (controls) were enrolled for the study. Eight hundred and twenty four follow-up samples of 225 breast carcinoma patients were also evaluated. The association of sialic acid forms, sialyltransferase and α-2–6 sialoproteins levels with presence and extent as well as prognosis of breast carcinoma was studied. Serum sialic acid forms and sialyltransferase revealed significantly elevated levels among untreated breast cancer patients as compared to the controls, patients with BBD as well as cancer patients in remission. Non-responders showed comparable levels of the markers with those found in breast cancer patients at the time of diagnosis. Higher levels of sialic acid forms at diagnosis were associated with poor prognosis. A positive correlation between serum levels of different forms of sialic acids and extent of malignant disease was observed. The changes in serum proteins with terminal α-2–6 sialic acid correlated well with alterations in the levels of sialic acid forms and sialyltransferase. Malignant tissues showed elevated levels of sialic acid and sialyltransferase as compared to surrounding normal tissues. The results suggested potential utility of these markers in evaluation of clinical outcome.     

The state and technological competition in France or colbertism in the 20th century

As in many western industrialized countries, the French State began to support technological research heavily after 1945. Public funds were mainly invested in high technologies (Nuclear, Aerospace, Computers) but as soon as awareness of technological backwardness of French industry made progress in the sixties, the French government decided to extend its financial support to other industrial sectors. A survey of the policies which have been worked out reveals that the French State has played the role of a bright entrepreneur without a technological and idustrial strategy, which explains why some of these policies are now at a dead end.     

University-industry linkages in the UK: What are the factors underlying the variety of interactions with industry?

This paper examines the different channels through which academic researchers interact with industry and the factors that influence the researchers’ engagement in a variety of interactions. This study is based on a large scale survey of UK academic researchers. The results show that university researchers interact with industry using a wide variety of channels, and engage more frequently in the majority of the channels examined - such as consultancy & contract research, joint research, or training - as compared to patenting or spin-out activities. In explaining the variety and frequency of interactions, we find that individual characteristics of researchers have a stronger impact than the characteristics of their departments or universities. Finally, we argue that by paying greater attention to the broad range of knowledge transfer mechanisms (in addition to patenting and spin-outs), policy initiatives could contribute to building the researchers’ skills necessary to integrate the worlds of scientific research and application.     

Prostate specific antigen in patients of benign prostate hypertrophy and carcinoma prostate

Prostate Specific Antigen (PSA) has emerged as the most applicable and important tumor marker for carcinoma prostate. In the present study PSA was determined in serum of healthy subjects, patients of benign prostate hypertrophy (BPH) and Carcinoma Prostate (Ca−P) to evaluate its diagnostic efficiency in day to day management of prostate cancer patients and in differentiating patients of early prostate cancer from those with BPH. Receiver operating characteristic curve (ROC) revealed 2 ng/ml and 10 ng/ml cut off serum PSA level for BPH and untreated carcinoma prostate patients (Ca−P). An extremely significant increase (P<0.0001) was observed in mean PSA concentration in BPH patients and adenocarcinoma prostate patients when compared to healthy males. Clinical relevance of PSA was highlighted by a case study of cancer patient prior to any therapy till death.     

pre-operative serum potassium levels and peri-operative outcomes in patients undergoing cardiac surgery

Although potassium is critical for normal electro physiology, the associations between pre-operative serum potassium level and peri-operative adverse events such as arrhythmias in cardiac surgery have not been examined in detail. The objective of this study was to determine the prevalence of abnormal pre-operative serum potassium levels and whether such levels were associated with adverse peri-operative events in 50 patients undergoing coronary artery bypass grafting. Intra-operative and post-operative arrhythmias, the need for cardio-pulmonary resuscitation, cardiac death and death due to any cause prior to discharge from the post-operative intensive care unit were studied. The incidence for adverse outcome was 0.5% for death, 0.5% for cardiac death and 2% for cardio pulmonary resuscitation in patients with hypokalemia (serum potassium level <3.5 meq. L⁻¹). Hypokalemia was found to be a predictor of serious peri-operative (OR:2.2; 95% Cl: 1.2–4.1) and post-operative arrhythmias (OR: 1.7;95%Cl: 1.0–2.7). Pre-operative potassium repletion is low cost and low risk treatment measure and the data from this study suggests that screening and repletion be considered in patients scheduled for cardiac surgery.     

Using Research Based Assessment Tools in Professional Development in Current Electricity

We present a practical way of adapting and using four research-based assessments for different purposes in an electricity and magnetism course for K-8 science teachers. The course is designed to accomplish conceptual change toward accepted scientific conceptions as well as introducing teachers to materials and activities appropriate for their classrooms. Our data support that using the research-based tests to identify alternative conceptions and discuss test results with teachers is a promising way to use the knowledge of alternative conceptions in professional development. We also identify some mismatches between the research of conceptual change and its use in programs of professional development.

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