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Barbara Comber 《English in Education》2007,41(2):7-26
This paper provides a retrospective account of three decades of my work as a literacy educator and researcher. Taking key insights from feminist sociologist, Dorothy Smith, including women's standpoint, the everyday world as problematic, institutional capture, a sociology for the people, I revisit my research on literacy, poverty and schooling. I argue that understanding better the effects of what we do in educational institutions, through collaborative research with teachers, can lead us to generate positive alternative equity‐driven practices. 相似文献
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Danuta Ro?? Przemys?aw Adamczyk Joanna Boinska Robert Szafkowski Irena Ponikowska Katarzyna Stankowska Barbara Góralczyk Barbara Ruszkowska-Ciastek 《Journal of Zhejiang University. Science. B》2015,16(5):404-411
Objective
The aim of this study was to evaluate the concentrations of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and the degree of homeostasis model assessment-insulin resistance (HOMA-IR) in patients with morbid obesity exposed to a three-week low-calorie diet and balneotherapy.Methods
The study included 33 patients (25 females and 8 males; mean age 46 years) with body mass index (BMI) values of >40 kg/m2. Evaluations of CRP, IL-6, TNF-α, lipid profile, HOMA-IR, and fasting glucose were carried out before (baseline data) and three weeks after the treatment. The control group consisted of 20 healthy volunteers (15 females and 5 males) with a mean age of 39 years and BMI values of ≤24.9 kg/m2.Results
In the blood of patients with morbid obesity we found significantly elevated levels of CRP, TNF-α, triglycerides, HOMA-IR and fasting glucose, but a decreased level of high density lipoprotein (HDL)-cholesterol, compared with the healthy individuals. The treatment resulted in about a 9.4% reduction in body weight from 122.5 to 111.0 kg and a significant decrease in the concentration of CRP, but no change in TNF-α or IL-6. HOMA-IR was significantly reduced.Conclusion
The decrease in CRP level without changes in TNF-α or IL-6 concentrations after the low-calorie diet and balneological treatment, suggests that an essential amount of adipose tissue must be removed before proper adipocyte function is restored. The decrease in HOMA-IR indicates an improvement in insulin sensitivity, which is beneficial in obese patients.97.
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Emergence of new industries from evolving technologies is critical to the global economy, yet has been relatively understudied due to the paucity of available data. This study draws lessons on industry emergence, by analyzing how a solid-state lighting (SSL) industry grew out of light emitting diode (LED) technologies that evolved for half a century, with participation by tens of thousands of researchers in universities, national laboratories, and firms. Using data on publications, patents, and firms combined with business history we trace the evolution of SSL through a succession of market niches. At times a few researchers with unorthodox research approaches made breakthroughs that greatly advanced particular technology trajectories and pushed LED research in unexpected directions. A succession of LED market niches advanced the technology and provided profits to incentivize continuing research while reducing cost and improving efficacy of LEDs. Innovating firms developed a thicket of patents and captured substantial profit, but were embroiled in extensive litigation that was ultimately resolved through cross-licensing. A major new generation of lighting products is now disrupting the traditional lighting industry. Although the leading incumbent lighting firms all invested early and heavily in SSL, the industry's future leadership is uncertain. 相似文献
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Duncan Pentland Kirsty Forsyth Donald Maciver Mike Walsh Richard Murray Linda Irvine 《知识管理研究与实践》2014,12(4):362-374
Basing treatment, policy and planning decisions on the best available research knowledge remains a central principle in modern health care around the world, yet many health professionals find acquiring and managing published research knowledge challenging. In this paper, we report on a Soft Systems Methodology-based collaborative action research initiative with a specialist mental health service from the United Kingdom's National Health Service. Our objective was to design and implement improvements to their knowledge acquisition and management activities in order to facilitate sustained and effective evidence-based practices. We report on both the factors found to impede effective research knowledge acquisition and management and the development of more integrated knowledge management processes designed to improve the situation. 相似文献
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E. Schreuders M. van Buuren R. J. Walsh H. Sijtsma M. Hollarek N. C. Lee L. Krabbendam 《Child development》2024,95(2):368-390
Longitudinal changes in trusting behavior across adolescence and their neural correlates were examined. Neural regions of interest (ROIs) included the medial prefrontal cortex (mPFC), dorsal anterior cingulate cortex (dACC), left anterior insula (AI), bilateral ventral striatum (VS), and right dorsal striatum (DS). Participants (wave 1 age: M = 12.90) played the investor in a Trust Game with an uncooperative trustee three times (1-year interval). Analyses included 77 primarily Dutch participants (33 females). Participants decreased their investments with wave. Furthermore, activity was heightened in mPFC, dACC, and DS during investment and repayment, and in right VS (investment) and AI (repayment). Finally, DS activity during repayment increased with wave. These findings highlight early–middle adolescence as an important period for developing sensitivity to uncooperative behavior. 相似文献