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Rats confronted with the onset of a light gradient display a transient increase in locomotion called theactivity response (AR) and a dark preference (Godsil & Fanselow, 2004). These experiments demonstrate that the magnitude of the AR can be blunted
with Pavlovian fear-conditioning procedures via associative and nonassociative fear. Although manifested in decreased locomotion,
the blunted AR effect was not due to increased freezing or immobility behaviors. Instead, rats displayed reduced rearing and
an increase in a class of behaviors calledstationary activity. These results suggest that the lighting differential supplied by the cue influences the topography of defensive behavior
and reduces the expression of freezing. This procedure provides a means by which to examine learned and unlearned defensive
responses to the same stimulus. 相似文献
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Giles LV Warburton DE Esch BT Fedoruk MN Rupert JL Taunton JE 《Journal of sports sciences》2012,30(3):261-267
The purpose of this study was to determine the effects of short-term normoxic and hypoxic exercise on plasma endothelin-1 and nitric oxide levels, and the relationship of arterial compliance and pulmonary artery pressure to endothelin-1. Seven endurance-trained males completed two incremental and two steady-state exercise tests performed at ventilatory threshold in normoxia and hypoxia (fraction of inspired oxygen = 0.14). Plasma endothelin-1was measured throughout steady-state tests. Arterial compliance using applanation tonometry, plasma nitric oxide and pulmonary artery pressure using Doppler echocardiography were measured before and after exercise. Small arterial compliance and pulmonary artery pressure significantly increased following exercise. There were no main effects of condition or time for plasma endothelin-1and nitric oxide levels. There were no significant relationships between plasma endothelin-1 and arterial compliance or pulmonary artery pressure. In conclusion, mechanisms other than the endothelial system may play a role in the exercise-induced changes in small artery compliance in this study population. Moderate hypoxia and a 30-minute steady-state exercise have limited effects on plasma endothelin-1 in endurance-trained males. 相似文献
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Bill Kennedy 《Publishing Research Quarterly》2010,26(3):187-192
A concise review is presented of the essential elements of the book publishing and bookselling business in a complex and diverse
market. Demographics create the diversity while Arabic is the one language spoken across a multitude of different countries.
Three features are common to all of these countries and they are: the dominance of English as the second language, education
has and will remain to be a priority, and economic pressures cause price sensitivity to be a major challenge especially in
the educational market segments. It is the price sensitivity as a key factor for the lack of respect for intellectual property
and copyright regulations. A review of distribution and retail stores is a very important topic in relation to this complex
collection of countries. The emergence of e-books is discussed especially in the educational, professional and reference market
segments. Finally, there is a review of the Arabic language publishers and local book fairs to bring this article to closure. 相似文献
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Bill Connor 《School Leadership & Management》2013,33(2):163-165
This paper is about the experience of preparation for incorporation in a sixth form college. The purpose of the paper is to take an analytical and reflective view of recent practice and developments which may have applications for all education managers facing externally imposed change. Its focus is on communication and consultation structures, the changing balance of power as institutions become independent of local authorities, and industrial relations in a new culture. It concludes that, without a full understanding of internal processes and structures and a strategy for strengthening them, colleges will continue to be ill‐equipped for survival as incorporated institutions. 相似文献
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