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971.
This paper explores knowledge transfers inside University–Industry collaborative research as the objective and scope of R&D activities vary. First, we contribute to a dynamic perspective on inter-organizational knowledge transfers by providing a new typology of University–Industry collaborative research. Second, we provide propositions related to contingent knowledge transfers, i.e. alignment between the nature of a project and the expected transfers. If such an alignment should ideally be built starting in the design phase, we demonstrate that a lack of alignment can be corrected as the collaborative research is iterated. Those iterations are experienced by partners as highly emotional events, influencing the rest of the collaborative work through what we call the pivot complex.  相似文献   
972.
973.
The objective of this study was to construct a teaching strategy for facilitating students’ conceptual understanding of the boiling concept. The study is based on 52 freshman students in the primary science education department. Students’ ideas were elicited by a test consisting of nine questions. Conceptual change strategy was designed based on students’ alternative conceptions. Conceptual change in students’ understanding of boiling was evaluated by administering a pre-, post- and delayed post-test. The test scores were analysed both by qualitative and quantitative methods. Statistical analysis using one-way ANOVA of student test scores pointed to statistically significant differences in the tests and total scores (p < 0.05). Quantitative analysis of students’ responses on each test revealed different schema about changing their knowledge system. Both qualitative and quantitative analyses suggest that the teaching activities facilitated students’ conceptual understanding. No statistically significant differences were found between post-test and delayed post-test scores, suggesting that the teaching strategy enabled students to retain their new conceptions in the long-term memory.  相似文献   
974.
Electrokinetic properties and morphology of PDMS microfluidic chips intended for bioassays are studied. The chips are fabricated by a casting method followed by polymerization bonding. Microchannels are coated with 1% solution of bovine serum albumin (BSA) in Tris buffer. Albumin passively adsorbs on the PDMS surface. Electrokinetic characteristics (electro-osmotic velocity, electro-osmotic mobility, and zeta potential) of the coated PDMS channels are experimentally determined as functions of the electric field strength and the characteristic electrolyte concentration. Atomic force microscopy (AFM) analysis of the surface reveals a “peak and ridge” structure of the protein layer and an imperfect substrate coating. On the basis of the AFM observation, several topologies of the BSA-PDMS surface are proposed. A nonslip mathematical model of the electro-osmotic flow is then numerically analyzed. It is found that the electrokinetic characteristics computed for a channel with the homogeneous distribution of a fixed electric charge do not fit the experimental data. Heterogeneous distribution of the fixed electric charge and the surface roughness is thus taken into account. When a flat PDMS surface with electric charge heterogeneities is considered, the numerical results are in very good agreement with our experimental data. An optimization analysis finally allowed the determination of the surface concentration of the electric charge and the degree of the PDMS surface coating. The obtained findings can be important for correct prediction and possibly for robust control of behavior of electrically driven PDMS microfluidic chips. The proposed method of the electro-osmotic flow analysis at surfaces with a heterogeneous distribution of the surface electric charge can also be exploited in the interpretation of experimental studies dealing with protein-solid phase interactions or substrate coatings.  相似文献   
975.
Studies addressing the connections between knowledge and organization structures can be divided into two classes. One class holds that a perspective on knowledge signals shortcomings of classical design principles and calls for flatter hierarchy and less specification of the production structure. Another class maintains that a knowledge perspective on organizations is at odds with any design perspective, whether classical or not, because the emergent, thoroughly social and practice-based nature of knowledge as knowing in action makes knowledge a useless and even dangerous beacon to designers: ex ante, knowledge is said to be fundamentally indeterminate and any attempt to ‘structure around knowledge’ may effectively drive out knowledge. To explore differences and possible bridges between these two calls of studies, the paper explores how both elements of the equation, organization structure and organizational knowledge, are to be conceived to ensure a meaningful connection between them. It is argued that the grouping focus in both defines the meeting place of organization structures and organizational knowledge, but shows that the involved knowledge and grouping concepts are not mutually compatible. It leads to a view where organization structures are seen as the ‘seeding’ background for knowledge integration processes that, in turn, constitute the patterns of work relationships envisioned in the designer's organizational decomposition and grouping. For illustration purposes, the paper presents the example of the Max Planck Institute that describes one possible way through the conceptual model presented in the paper.  相似文献   
976.
The continuous use of synthetic hormones as contraceptive pill or hormonal replacement therapy among women is increasing day by day. The widespread use of different formulations as oral contraceptives by women throughout their reproductive cycle has given rise to a serious concern for studying the effects of oral contraceptives on enzymatic profile and DNA damage in peripheral blood lymphocytes among users. The present study was carried out on women taking oral contraceptives. The study was based on the questionnaire having the information of reproductive history, fasting, age, health, nature of menstrual cycle, bleeding and other disease. The profile of the blood serum enzymes i.e. alkaline phosphatase (ALP), gamma glutamyl transferase (GGT), lactate dehydrogenase (LDH), aminotransferases (SGOT and SGPT), serum proteins (albumin and globulin) and DNA damage in lymphocytes was studied among users and non-users. The results of the present study suggest that OCs not only effects enzymatic activity but also results in DNA damage that may vary with the duration of using oral contraceptives. A significant increase in LDH, GGT, SGPT, SGOT, globulin and decrease in ALP as well as albumin was found among users as compared to non-users. The observed DNA damage was more in users as compared to non-users. Hormonal contraceptives seem to exert DNA damage and also have significant effects on blood serum enzymes.  相似文献   
977.
BML monitors consumer book purchases in Britain via its Books & Consumers survey. RR Bowker tracks US consumer book purchases via its PubTrack Consumer survey. This report compares the results of the two surveys. In 2008, the US consumer market was around ten times the size of its UK equivalent, but a higher proportion of British than US consumers bought books. Book buyers in each country were similar in terms of gender and age, but slightly more ‘up market’ in the US than Britain. Adult fiction and hardbacks accounted for a higher proportion of book purchases in the US than in Britain, but with variations in the mix of genres bought. Chain bookshops remained the largest channel for book purchases in Britain, despite losing share in recent years. The internet overtook the chains in the US in 2008, with Britain around 3 years behind in terms of internet share.  相似文献   
978.
Increasingly, museums are seeking to incorporate indigenous perspectives into their exhibits, programs, and collections management policies. Despite its history and close proximity to Hawaiians, Bishop Museum has neither a long nor an unblemished record of consulting the indigenous community. Within the last three years, there has been a theft/removal of sacred objects, a lawsuit involving repatriation of Hawaiian remains, demonstrations and state government hearings concerning the Bishop's interpretation of archaeological sites, as well as more positive activity; e.g., a renewed interest in exhibiting Hawaiian culture. While factionalism within the indigenous community complicates matters, many of the museum's problems are an outgrowth of its own decisions: lucrative contracts have not been without cost, and internal dissension has resulted in such high staff turnover that the museum's professional capability has been publicly called into question by Hawaiians (and others). As Hawaiians assume a more active role, their 106-year relationship with Bishop Museum is being redefined. (Note: “Hawai'i” is used here to refer to the southernmost island in the chain; “Hawaii” designates the entire chain, the state).  相似文献   
979.
The rapid growth of the Web has increased the difficulty of finding the information that can address the users’ information needs. A number of recommendation approaches have been developed to tackle this problem. The increase in the number of data providers has necessitated the development of multi-publisher recommender systems; systems that include more than one item/data provider. In such environments, preserving the privacy of both publishers and subscribers is a key and challenging point. In this paper, we propose a multi-publisher framework for recommender systems based on a client–server architecture, which preserves the privacy of both data providers and subscribers. We develop our framework as a content-based filtering system using the statistical language modeling framework. We also introduce AUTO, a simple yet effective threshold optimization algorithm, to find a dissemination threshold for making acceptance and rejection decisions for new published documents. We further propose a language model sketching technique to reduce the network traffic between servers and clients in the proposed framework. Extensive experiments using the TREC-9 Filtering Track and the CLEF 2008-09 INFILE Track collections indicate the effectiveness of the proposed models in both single- and multi-publisher settings.  相似文献   
980.
For several years the National Technical Institute for the Deaf (NTID) at the Rochester Institute of Technology has offered a course that focuses on preparing video resumes. Professionals from the Instructional Television Department and the National Center of Employment for the Deaf have collaborated with communication instructors to develop this option for NTID students. This paper describes the instruction and evaluation process from the perspective of NTID instructors, students, and other technical professionals. Employers who have hired NTID students and those who have no familiarity with deaf employees also participated in the evaluation. Their comments give valuable insights into the often different perspectives of deafness between those who have worked with deaf employees and those who lack such experience. Video resumes were found to be a viable tool in the job search, and the process of preparing the video was found to be a stimulating and rewarding experience for the participating students.  相似文献   
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