Compression garments and cerebral blood flow: Influence on cognitive and exercise performance

This study aimed to describe the effect of compression garments on middle cerebral artery blood flow velocity (MCA_v) in relation to cognitive and exercise performance whilst cycling. In a randomised-controlled-cross-over design, 15 well-trained male cyclists were recruited to participate in three identical trials wearing loose fitting shorts (control), low-grade, or medium-grade compression garments. The protocol involved four 8?min increments of cycling at 30%, 50%, 70%, and 85% maximal power output and a 4?km time-trial. Participants undertook a cognitive Stroop task at baseline and at the midpoint of each increment. MCA_v was monitored with Transcranial Doppler Ultrasonography. Mean arterial pressure (MAP) and partial pressure of end-tidal CO₂ (P_etCO₂) were measured throughout. MCA_v, MAP, P_etCO₂, and reaction time of the complex Stroop task were influenced by exercise intensity, but not compression garments. Compression garments significantly affected cognitive accuracy in the complex Stroop task such that low-grade compression appeared to enhance cognitive accuracy in comparison to the control condition at the highest intensity (p?=?.010). Time-trial performance did not differ between the control (338.0?±?17.3 s), low-grade (338.7?±?18.7 s), or medium-grade (342.2?±?19.3 s) conditions (p?=?.114). Compression garments did not affect MCA_v during exercise or time-trial performance, but compression may be beneficial for improved cognitive accuracy during high-intensity exercise. Further research is required to elucidate the potential impact on cognitive performance.     

The Impact of Alumni Status on Institutional Giving by Faculty and Staff

This study explores the association between propensity toward giving and personal and positional characteristics of faculty and staff across 3 years within a large, public, multi-campus higher education institution. Informed by the literatures on organizational identity and commitment, faculty and staff giving, and the higher education workforce, the study employs a hurdle analysis to estimate the predictors of likelihood of donating (the hurdle) and the amount given among those who donate. Following up on earlier research by the authors that demonstrated that academic employees and employees who are institutional alumni are more likely to give, the present study explores the interaction between these roles and offers a more powerful model for predicting the amount given. The results of this study have implications for understanding how organizational commitment and identification may be relevant in addressing giving, for institutional fundraising, and for building institutional loyalties.     

An Examination of Coursera as an Information Environment: Does Coursera Fulfill its Mission to Provide Open Education to All?

In terms of international education, the concept of online education seems to be a growing trend. Edxonline.org, Minervaproject.com, and Udacity.com are all new massive online open courses (MOOCs)—education websites similar to Coursera offering students the ability to receive the best education from elite universities entirely online. The most tantalizing promise of a company like Coursera is the role it might play in improving education for the world's have-nots: high school dropouts, the global poor, and those less able to self-teach.     

Effects of purposeful soccer heading on circulating small extracellular vesicle concentration and cargo

BackgroundConsidering the potential cumulative effects of repetitive head impact (HI) exposure, we need sensitive biomarkers to track short- and long-term effects. Circulating small extracellular vesicles (sEVs) (<200 nm) traffic biological molecules throughout the body and may have diagnostic value as biomarkers for disease. The purpose of this study was to identify the microRNA (miRNA) profile in circulating sEVs derived from human plasma following repetitive HI exposure.MethodsHealthy adult (aged 18–35 years) soccer players were randomly assigned to one of 3 groups: the HI group performed 10 standing headers, the leg impact group performed 10 soccer ball trapping maneuvers over 10 min, and the control group did not participate in any soccer drills. Plasma was collected before testing and 24 h afterward, and sEVs were isolated and characterized via nanoparticle tracking analysis. Next-generation sequencing was utilized to identify candidate miRNAs isolated from sEVs, and candidate microRNAs were analyzed via quantitative polymerase chain reaction. In silico target prediction was performed using TargetScan (Version 7.0; targetscan.org) and miRWalk (http://mirwalk.umm.uni-heidelberg.de/) programs, and target validation was performed using luciferase reporter vectors with a miR-7844-5p mimic in human embryonic kidney (HEK) 293T/17 cells.ResultsPlasma sEV concentration and size were not affected across time and group following repetitive HI exposure. After 24 h, the HI read count from next-generation sequencing showed a 4-fold or greater increase in miR-92b-5p, miR-423-5p, and miR-24-3p and a 3-fold or greater decrease in miR-7844-5p, miR-144-5p, miR-221-5p, and miR-22-3p. Analysis of quantitative polymerase chain reaction revealed that leg impact did not alter the candidate miRNA levels. To our knowledge, miR-7844-5p is a previously unknown miRNA. We identified 8 miR-7844-5p mRNA targets: protein phosphatase 1 regulatory inhibitor subunit 1B (PPP1R1B), LIM and senescent cell antigen-like domains 1 (LIMS1), autophagy-related 12 (ATG12), microtubule-associated protein 1 light chain 3 beta (MAP1LC3B), integrin subunit alpha-1 (ITGA1), mitogen-activated protein kinase 1 (MAPK1), glycogen synthase kinase 3β (GSK3β), and mitogen-activated protein kinase 8 (MAPK8).ConclusionCollectively, these data indicate repetitive HI exposure alters plasma sEV miRNA content, but not sEV size or number. Furthermore, for the first time we demonstrate that previously unknown miR-7844-5p targets mRNAs known to be involved in mitochondrial apoptosis, autophagy regulation, mood disorders, and neurodegenerative disease.     

Including students with disabilities in Education for All: lessons from Ethiopia

This article addresses the inclusion of students with disabilities into the Education for All and Sustainable Development Goals agenda through a case study of Ethiopia, a country aiming to promote inclusive education amidst rapidly rising school enrolments. The article begins with a review of debates concerning inclusive education in the Global South and the strategy taken by Ethiopia. It then examines how inclusive education is currently being implemented drawing on recent fieldwork at rural and urban schools in Tigray province. Through interviews, participant observation, and focus groups, we found that teachers and school administrators are generally in favour of mainstreaming children with disabilities into ‘normal’ schools. However, insufficient training of teachers and itinerant teachers along with shortages of teaching materials and resources present major challenges to addressing special education needs.     

“Is This a Boy or a Girl?”: Rethinking Sex-Role Representation in Caldecott Medal-Winning Picturebooks, 1938–2011

A number of previous studies have addressed gender role-stereotyping in Caldecott Award-winning picturebooks. Building upon the extensive scholarship examining representations of females in Caldecott books, this current study offers a critical investigation of how gender is represented in Caldecott Medal-winning literature from 1938 to 2011 by exploring the ways in which “femininity” and “masculinity,” biological sex, and gender are constructed in these texts. The investigators briefly address author and illustrator gender and the representations of males and females as characters or images in pictures and text before departing from previous scholarship to offer a rereading of books that feature “ungendered” leading characters, those that are not identified in the text as being either “male” or “female” and are therefore open to the interpretation of individual readers. By resisting cultural cues and normative constructions of gender and biological sex, these ungendered depictions extend the range of possible ways in which readers may see themselves or those in their lives represented in Caldecott Medal-winning picturebooks.     

Evidence of alphabetic knowledge in writing: connections to letter and word identification skills in preschool and kindergarten

The writing skills of 286 children (157 female and 129 male) were studied by comparing name writing and letter writing scores from preschool to kindergarten with letter and word reading scores over the same time period. Two rubrics for scoring writing were compared to determine if scores based on multiple components (i.e., letter formation, orientation on the vertical axis, left–right orientation, and correct letter sequencing) would better reflect differences in children’s writing knowledge in preschool and kindergarten than rubrics composed of one component (i.e., letter formation only). While developmental changes in writing scores were found, little additional information was provided by multiple component scoring rubrics compared to the single component rubric. Letter writing scores were more strongly related to letter and word reading scores than name writing scores but neither writing score was predictive of growth. Implications of the findings for intentional/systematic writing instruction in preschool curricula are discussed.     

Physical Disability,Stigma, and Physical Activity in Children

Using the stereotype content model as a guiding framework, this study explored whether the stigma that able‐bodied adults have towards children with a physical disability is reduced when the child is portrayed as being active. In a 2 (physical activity status) x 2 (ability status) study design, 178 university students rated a child described in one of four vignettes on 12 dimensions of perceived warmth and competence. Results revealed a main effect of ability status on warmth (p < 0.001) such that children with a physical disability were rated significantly higher in perceived warmth than able‐bodied children, regardless of activity status (d = 0.86). Also, there was a significant interaction (p = 0.02) of ability and activity status on perceived competence, indicating that ratings of perceived competence were significantly higher for active children with a physical disability than for all other children (d = 0.54–0.64). Results suggest that physical activity should be explored as a way to mitigate the stigmatisation of children with a physical disability.     

Externally Contingent and Unstable Self‐Worth as Predictors of Depression in College Women: A 3‐Month Study

Undergraduate women completed measures of externally contingent self‐worth, self‐esteem instability, and depression at the beginning (Time 1) and again 3 months later near the end (Time 2) of an academic semester. Findings indicated that when Time 1 depression scores were controlled for, each Time 1 facet of self‐esteem made significant contributions to Time 2 depression scores. Implications of these findings for the counseling of depressed college students are discussed.