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121.
Richard Heidler 《Minerva》2011,49(4):461-488
Scientific collaboration can only be understood along the epistemic and cognitive grounding of scientific disciplines. New scientific discoveries in astrophysics led to a major restructuring of the elite network of astrophysics. To study the interplay of the epistemic grounding and the social network structure of a discipline, a mixed-methods approach is necessary. It combines scientometrics, quantitative network analysis and visualization tools with a qualitative network analysis approach. The centre of the international collaboration network of astrophysics is demarcated by identifying the 225 most productive astrophysicists. For the years 1998?C1999 and 2001?C2006 four co-authorship networks are constructed comprehending each a two year period. A visualization of the longitudinal network data gives first hints on the structural development of the network. The network of 2005?C2006 is analyzed in depth. Based on cohesion analysis tools for network analysis, two main cores and three smaller ones are identified. Scientists in each core and additionally in structurally interesting positions are identified and 17 qualitative expert interviews are conducted with them. The visualization of the network of 2005?C2006 is used in the interviews as a stimulus for the interviewees. An analysis of the three most often used keywords of the 225 astrophysicists is included and combined with the other data. The triangulation of these approaches shows that major epistemic changes in astrophysics, e.g. the discovery of the accelerating expansion of the universe, together with technical and organizational innovations, leads to a restructuring of the network of the discipline. The importance of a combination of qualitative and quantitative network analysis tools for the understanding of the interplay of cognitive and social structure in the sociology of science is substantiated.  相似文献   
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ABSTRACT

Interval exercise training is increasingly recommended to improve health and fitness; however, it is not known if cardiovascular risk is different from continuous exercise protocols. This systematic review with meta-analyses assessed the effect of a single bout of interval exercise on cardiovascular responses that indicate risk of cardiac fibrillation and infarction compared to continuous exercise. Electronic databases Medline, CINAHL, Embase, Scopus and Cochrane were searched. Key inclusion criteria were: (1) intervals of the same intensity and duration followed by a recovery period and (2) reporting at least one of blood pressure, heart rate variability, arterial stiffness or function. Cochrane Risk of Bias tool and GRADE approach were used. Meta-analyses found that systolic blood pressure responses to interval exercise did not differ from responses to continuous exercise immediately (MD 8 mmHg [95% CI ?32, 47], p = 0.71) or at 60 min following exercise (MD 0 mmHg [95% CI ?2, 1], p = 0.79). However, reductions in diastolic blood pressure and flow-mediated dilation with interval exercise were observed 10–15 min post-exercise. The available evidence indicates that interval exercise does not convey higher cardiovascular risk than continuous exercise. Further investigation is required to establish the safety of interval exercise for clinical populations.  相似文献   
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