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891.
R. L. Gupta K. Ramachandran Monika J. S. Chowhan 《Indian journal of clinical biochemistry : IJCB》1996,11(1):59-61
Urinary excretion of beta-aminoisobutyric acid (BAIB), was determined in 28 active and 12 inactive bladder cancer patients.
Mean excretion of BAIB was higher in active cancer patients-187.8 mg/24 hours whereas it was 120.4 mg/24 hours in inactive
cancer patients. The increased BAIB excretion in both disease groups was independent of tumour stage. BAIB appears to be a
useful diagnositic aid in the assessment of bladder cancer patients. 相似文献
892.
K. S. Motghare Anil Bhutey B. B. Murrhar Madhur Gupta A. W. Meshram Y. Balsubramanium 《Indian journal of clinical biochemistry : IJCB》2001,16(2):213-215
With the growing interest in the concept of free radicals in the pathogenesis of myocardial ischemia, it was thought worthwhile
to study the changes in lipid peroxides and antioxidant enzyme glutathione peroxidase (GPx) in ischemic heart disease (IHD).
The study was carried out on 76 patients of IHD-38 of acute myocardial infarction (AMI) and 38 of stable ischemic heart disease
(SIDH). They were age and sex matched with 38 normal healthy controls. A significant increase (p<0.001) in lipid peroxides
as malondialdehyde (MDA) (5.9±0.7 mmol/L) and a decrease in GPx (24.6±2.2 U/gmHb) was found in patients of AMI when compared
with controls. There was no significant difference in these values in SIHD. Thus this study confirms the earlier findings
that MDA and GPx are useful parameters in IHD and their magnitude is dependent on severity and/or duration of ischemia. We
suggest that these tests would be of use in smaller institutions with limited facilities. 相似文献
893.
894.
Hasan Kahveci Cuneyt Tayman Fuat Laoğlu Hüseyin Tugrul Celik Nazan Kavas Ömer Kılıç Salih Aydemir 《Indian journal of clinical biochemistry : IJCB》2016,31(1):38-42
Infants with respiratory distress syndrome (RDS) may suffer from severe hypoxia, asphyxia. In this study, we aimed to evaluate serum ischemia-modified albumin (IMA) level as a diagnostic marker for hypoxia in preterm infants with RDS. Thirty-seven premature newborns with RDS were allocated as the study group and 42 healthy preterm neonates were selected as the control group. IMA was measured as absorbance unit (ABSU) in human serum with colorimetric assay method which is based on reduction in albumin cobalt binding. IMA levels were significantly higher in neonates with RDS as compared to the control group (P < 0.001). Cut-off value of IMA (ABSU) was 0.72, the sensitivity level was 91.9 %, the specificity was 78.6 %, positive predictive value was 79.1 % and negative predictive value was 91.7 % at RDS. Area under curve values was 0.93 (P < 0.001; 95 % CI, 0.88–0.98) in the receiver operating characteristic curve. We concluded that elevated blood IMA levels might be accepted as a useful marker for hypoxia in newborn with RDS. 相似文献
895.
K. Srikrishna A. S. Kanagasabapathy Lily John 《Indian journal of clinical biochemistry : IJCB》1994,9(1):5-8
The urinary excretion patterns of N-acetyl-β-D-glucosaminidase (NAG), alanine aminopeptidase (AAP) and protein/creatinine ratio (UP/UCR) were studied in 133 diabetic subjects under treatment, 7 patients with established diabetic nephropathy (DN) and 79 carefully selected (age-matched) healthy subjects. NAG, AAP and UP/UCR were highly elevated in DN, while in diabetics urinary NAG levels correlated well with the degree of long-term metabolic control indicated by glycosylated hemoglobin (GHB or Hba1). Both AAP and UP/UCR were found to be more sensitive than NAG, but less specific. Urinary NAG and AAP assays thus offer simple, sensitive and non-invasive techniques for prognostic indication of the onset of microangiopathic changes in long-term diabetic subjects. 相似文献
896.
Diabetics showed significantly raised levels of total and LDL cholesterol, (257.0±68.88 mg% 173.5±67.7mg% respectively) compared
to controls matched with age, sex and socioeconomic status. No significant difference was observed in these parameters in
diabetics with and without retinopathy. 相似文献
897.
Yeldose Sonu S. S. Avinash Sreekantha K. Arun Kumar M. Malathi A. R. Shivashankara 《Indian journal of clinical biochemistry : IJCB》2016,31(3):326-331
Given the paucity of studies conducted to know the effect of suddenness and earlier onset of endocrinological changes associated with hysterectomy, on the serum and urinary levels of calcium, magnesium and phosphate the present study was conducted to compare the levels of calcium, magnesium and phosphate in serum and urine of hysterectomised and natural menopausal south Indian women. This is a cross-sectional observational study. The study included three groups of 30 healthy premenopausal, 30 early surgical menopausal and 30 natural post menopausal women. Women suffering from any endocrine disease were excluded. Analysis was performed in serum and urine sample. The levels of calcium, magnesium and phosphate in serum and calcium/creatinine, magnesium/creatinine and phosphate/creatinine ratio were estimated in urine by spectrophotometric method. Hysterectomised women (serum calcium: 8.7 ± 0.09 mg/dl; urine calcium/creatinine: 0.16 ± 0.02) have significantly low serum calcium (p < 0.001) and high urinary calcium/creatinine (p = 0.002) ratio and post menopausal women (serum magnesium: 2.1 ± 0.03; serum phosphate: 4.4 ± 0.16; urinary calcium/creatinine: 0.17 ± 0.02; urinary magnesium/creatinine: 0.09 ± 0.01) have significantly high serum magnesium (p = 0.016), serum phosphate (p = 0.043) and high urinary calcium/creatinine (p = 0.002), magnesium/creatinine ratio (p = 0.025) compared to healthy pre menopausal women. Post menopausal women (serum calcium: 9.1 ± 0.08) have significantly high serum calcium and phosphate compared to hysterectomised women (serum phosphate: 3.93 ± 0.11). Hysterectomised women have significantly low serum calcium, oestrogen and high urinary calcium/creatinine ratio compared to healthy premenopausal women and low serum calcium and low serum phosphate compared to natural postmenopausal women. Natural postmenopausal women had low serum oestrogen and high serum magnesium, serum phosphate, urinary calcium creatinine ratio and urinary magnesium creatinine ratio compared to healthy premenopausal women. 相似文献
898.
In this study the effect of thiazide diuretic compound on the protein and cholesterol contents in the testes of albino rats
as the experimental model. The drug thiazide was administered orally daily for 10,20 and 30 days at the dose of 100mg/kg body
weight. Total protein decrease in the testes of rats were evidenced may be due to the side effects of thiazide drug compound
which is linked with the hyponatremia and protein metabolism. An elevated level of cholesterol contents observed in thiazide
treated rats also revealed that the side effect of drug compound thiazide and also may be due to the stimulation of catecholamine
which is stimulated therefore, the biochemical estimation such as protein and cholesterol in the testes after the thiazide
treatment determined the effectiveness of diuretic drug compound would provide clinical evidences of their side effects. 相似文献
899.
Study on arsenic level in ground water of Delhi using hydride generator accessory coupled with atomic absorption spectrophotometer 总被引:1,自引:0,他引:1
Sanjeev Lalwani T. D. Dogra D. N. Bhardwaj R. K. Sharma O. P. Murty Aarti Vij 《Indian journal of clinical biochemistry : IJCB》2004,19(2):135-140
Surveillance of drinking water is essentially a health measure intended to protect the public from water borne diseases. Hydride
generator accessory coupled with atomic absorption spectrophotometer was used to analyze arsenic level in 49 ground water
samples collected from different areas of Delhi. Arsenic level in ground water samples was in the range of 0.0170 to 0.100
ppm (Mean-0.0431, Standard Deviation-0.0136, Std. error of Mean-0.00194) with minimum concentration at Raney Well No. 7 (0.0170
ppm) and maximum at Kotla Mubarak Pur (0.100 ppm). Arsenic containing sediments and percolation of chemicals into soil as
the result of dumping of garbage rich in chemicals into open landfills could be the possible source of arsenic in ground water
of Delhi. Extensive survey and continuous monitoring is required to be made to assess the magnitude of problem and earlier
intervention. 相似文献
900.
Peter K. Dunn 《Teaching Statistics》2005,27(2):37-41
Rolling dice and tossing coins can still be used to teach probability even if students know (or think they know) what happens in these experiments. This article considers many simple variations of these experiments which are interesting, potentially enjoyable and challenging. Using these variations can cause students (and teachers) to think again about the statistical issues involved – and learn in the process. 相似文献