Exploring ancestral phenotypes and evolutionary development of the mammalian middle ear based on Early Cretaceous Jehol mammals

We report a new Cretaceous multituberculate mammal with 3D auditory bones preserved. Along with other fossil and extant mammals, the unequivocal auditory bones display features potentially representing ancestral phenotypes of the mammalian middle ear. These phenotypes show that the ectotympanic and the malleus-incus complex changed notably during their retreating from the dentary at various evolutionary stages and suggest convergent evolution of some features to extant mammals. In contrast, the incudomalleolar joint was conservative in having a braced hinge configuration, which narrows the morphological gap between the quadroarticular jaw joint of non-mammalian cynodonts and the incudomalleolar articulations of extant mammals. The saddle-shaped and abutting malleus-incus complexes in therians and monotremes, respectively, could have evolved from the braced hinge joint independently. The evolutionary changes recorded in the Mesozoic mammals are largely consistent with the middle ear morphogenesis during the ontogeny of extant mammals, supporting the relation between evolution and development.     

Juggling competing activities: academic staff as doctoral candidates

ABSTRACT

This article explores the experiences of a group of established academic staff in New Zealand and the UK, as they undertake a doctorate in their home institutions. Our interest is in how individuals negotiate this dual status from a cultural-historical activity theory (CHAT) stance that explores how rules, tools, community and divisions of labour, and interacting activity systems, shape doctoral experiences. The focus in this article, having analysed their detailed narrative accounts, is on how academics experience three interdependent activity systems: those surrounding the thesis, the institutional context, and the home-life spheres. Issues related to time, workload and supervision issues, variability in collegial support and impact on personal priorities and time emerged. There is a range of particularities – from easy access to resources/supervisors to inflexible institutional regulations – applicable to this group of doctoral candidates. Negotiating life as an academic with concurrent doctoral candidature provides positive outcomes in terms of teaching, research confidence and general personal and professional development. However, a range of difficulties can also be encountered, particularly in relation to personal and professional relationships, and workload management.     

Mediating effects of resistance training skill competency on health-related fitness and physical activity: the ATLAS cluster randomised controlled trial

The purpose of this study was to examine the mediating effect of resistance training skill competency on percentage of body fat, muscular fitness and physical activity among a sample of adolescent boys participating in a school-based obesity prevention intervention. Participants were 361 adolescent boys taking part in the Active Teen Leaders Avoiding Screen-time (ATLAS) cluster randomised controlled trial: a school-based program targeting the health behaviours of economically disadvantaged adolescent males considered “at-risk” of obesity. Body fat percentage (bioelectrical impedance), muscular fitness (hand grip dynamometry and push-ups), physical activity (accelerometry) and resistance training skill competency were assessed at baseline and post-intervention (i.e., 8 months). Three separate multi-level mediation models were analysed to investigate the potential mediating effects of resistance training skill competency on each of the study outcomes using a product-of-coefficients test. Analyses followed the intention-to-treat principle. The intervention had a significant impact on the resistance training skill competency of the boys, and improvements in skill competency significantly mediated the effect of the intervention on percentage of body fat and the combined muscular fitness score. No significant mediated effects were found for physical activity. Improving resistance training skill competency may be an effective strategy for achieving improvements in body composition and muscular fitness in adolescent boys.     

Access to human,animal, and environmental journals is still limited for the One Health community

Objective

“One Health” is an interdisciplinary approach to evaluating and managing the health and well-being of humans, animals, and the environments they share that relies on knowledge from the domains of human health, animal health, and the environmental sciences. The authors'' objective was to evaluate the extent of open access (OA) to journal articles in a sample of literature from these domains. We hypothesized that OA to articles in human health or environmental journals was greater than access to animal health literature.

Methods

A One Health seminar series provided fifteen topics. One librarian translated each topic into a search strategy and searched four databases for articles from 2011 to 2012. Two independent investigators assigned each article to human health, the environment, animal health, all, other, or combined categories. Article and journal-level OA were determined. Each journal was also assigned a subject category and its indexing evaluated.

Results

Searches retrieved 2,651 unique articles from 1,138 journals; 1,919 (72%) articles came from 406 journals that contributed more than 1 article. Seventy-seven (7%) journals dealt with all 3 One Health domains; the remaining journals represented human health 487 (43%), environment 172 (15%), animal health 141 (12%), and other/combined categories 261 (23%). The proportion of OA journals in animal health (40%) differed significantly from journals categorized as human (28%), environment (28%), and more than 1 category (29%). The proportion of OA for articles by subject categories ranged from 25%–34%; only the difference between human (34%) and environment (25%) was significant.

Conclusions

OA to human health literature is more comparable to animal health than hypothesized. Environmental journals had less OA than anticipated.Keywords (Medical Subject Headings) Publishing, Periodicals as Topic, Access to Information, Veterinary Medicine, Environment, Environmental Health, Medicine“One Health” is an integrated, transdisciplinary approach to solve complex problems at the diverse interfaces shared by humans, animals, and the environment [1]. The One Health approach to evaluating and managing the health and well-being of humans, animals, and the environments that they share relies on knowledge from the domains of human health, animal health, and the environmental sciences. Although there is a growing body of literature about the development of the One Health concept as documented by Pepper, Carrigan, Shurtz, and Foster [2], this literature is not the same as the combination of literature from the three domains that is applied in service of One Health. Every discipline related to One Health has its unique mindset and language, with corresponding lists of acronyms that are frequently an impediment to effective communication across the participating professions. Relevant papers guiding a One Health approach may never specifically use “One Health” as a term or concept.To promote better communication and collaboration among health professionals and environmental scientists, a public monthly One Health Intellectual Exchange Group (IEG) hosted by the North Carolina Biotechnology Center was launched in 2009. In 2011, faculty from the North Carolina State University College of Veterinary Medicine, University of North Carolina''s Gillings School for Global Public Health, Duke Global Health Institute, and Nicholas School of the Environment at Duke University expanded the IEG series into a weekly seminar course with eight One Health focus areas [3]. The eight focus area modules were the following: an introduction to One Health; environmental health and ecology; the human and animal bond; zoonoses and emerging infectious diseases; food and water safety; disease surveillance, informatics, and disaster preparedness; benefits of comparative medicine; and policy and education (Appendix A, online only). Each seminar speaker recommended papers to read prior to the session to provide a foundation for the topic because student backgrounds and majors were quite diverse. Represented student majors included master''s of public health, master''s of animal science, doctor of veterinary medicine, graduate-level environmental sciences, and undergraduate-level biochemistry, engineering, and biology.Open access (OA) to relevant literature is very important to scholars and practitioners working on interdisciplinary problems. The One Health Proof of Concept Workgroup found that few studies assess outcomes in human, animal, and environmental spheres simultaneously [4], making it important to be able to access articles from each of the three domains to get a more complete picture.The objective of this study was to evaluate the extent of OA to journal articles in a sample of literature relevant to One Health from the human, animal, and environmental domains. Working in a college of veterinary medicine and supporting faculty, staff, and students addressing interdisciplinary problems under the One Health umbrella [5], the authors were familiar with the extent of OA in human biomedical and public health literature and the literature of veterinary medicine but were less familiar with environmental journals. In light of general availability of environmental information and OA to publications such as Environmental Health Perspectives, we thought it likely that environmental literature would be relatively open compared to the other subject areas. Therefore, we hypothesized OA to articles from human health or environmental journals was greater than access to animal health literature. We chose to look at article-level subject categorization and access, as well as journal-level categorization and access, because they might differ. Article-level access relates more to authors'' decisions about OA for a content domain, while journal-level access and subject categorization are driven by publishers and associations. Understanding the distinction and having data would inform our efforts to promote increased OA to this literature.