Beyond the Blockbuster: Good Exhibitions in Small Packages

Many American and European art museums are now featuring small, highly-focused shows in their exhibition programs. In 1990, the Indianapolis Museum of Art organized an exhibition that reunited, for the first time in a century, the four landscape paintings created by neo-impressionist Georges Seurat during the last summer of his life. Using Seurat at Gravelines: The Last Landscapes as an example, this article addresses the advantages — for museums and their visitors — of the small temporary exhibition.     

Age,aging and mega-serials in Tamil Nadu

This qualitative, exploratory study examines issues of age and aging surrounding mega-serial (daily soap opera) production in Tamil Nadu, India. This study is timely for demographic reasons (a rapidly aging Indian population) and for the centrality of mega-serials to India’s entertainment landscape, coupled with the genre’s long history of engaging global audiences with real-world social issues. Two data sources are utilized: focus groups with 16 mega-serial viewers and interviews with 25 members of the Tamil mega-serial industry. Situated in scholarship on gerontology/age studies and media/culture industry studies, analysis yields two broad themes related to (a) representations of age/aging and elder-oriented storylines in contemporary Tamil mega-serials and (b) recent industry changes that may forestall mega-serials’ potential to center age and aging as core narrative elements. Overall, evidence points to an industry and audience(s) in considerable transition.     

Injectable hybrid inorganic nanoscaffold as rapid stem cell assembly template for cartilage repair

Cartilage injuries are often devastating and most cannot be cured because of the intrinsically low regenerative capacity of cartilage tissues. Although stem-cell therapy has shown enormous potential for cartilage repair, the therapeutic outcome has been restricted by low survival rates and poor chondrocyte differentiation in vivo. Here, we report an injectable hybrid inorganic (IHI) nanoscaffold that facilitates fast assembly, enhances survival and regulates chondrogenic differentiation of stem cells. IHI nanoscaffolds that strongly bind to extracellular matrix (ECM) proteins assemble stem cells through synergistic 3D cell–cell and cell–matrix interactions, creating a favorable physical microenvironment for stem-cell survival and differentiation in vitro and in vivo. Additionally, chondrogenic factors can be loaded into nanoscaffolds with a high capacity, which allows deep, homogenous drug delivery into assembled 3D stem-cell-derived tissues for effective control over the soluble microenvironment of stem cells. The developed IHI nanoscaffolds that assemble with stem cells are injectable. They also scavenge reactive oxygen species and timely biodegrade for proper integration into injured cartilage tissues. Implantation of stem-cell-assembled IHI nanoscaffolds into injured cartilage results in accelerated tissue regeneration and functional recovery. By establishing our IHI nanoscaffold-templated 3D stem-cell assembly method, we provide a promising approach to better overcoming the inhibitory microenvironment associated with cartilage injuries and to advance current stem-cell-based tissue engineering.     

The chaotic late Qing and early Republican periods

This article excavates some of the core intellectual elements underlying the Xinhai Revolution of 1911 and their historical genealogies. Rather than focusing on the modern nature of the revolution, Mizoguchi locates the revolution within the context of traditional Chinese culture and thought. A central focus of the article is the notion of “self-governance” (zizhi), which played a central role in determining the shape the revolution was to ultimately take. It analyzes the social thought of key figures of the Qing period, showing how in modified guise, core Confucian ethical concepts such as the dichotomy between the private (si) and public (gong) as well as utopian concepts such as datong (great harmony) determined the deep structure of revolutionary thought at the end of the Qing and into the Republican and Communist periods.     

The influence of lower limb amputation level on the approach in the amputee long jump

In this study, we investigated the adjustments to posture, kinematic and temporal characteristics of performance made by lower limb amputees during the last few strides in preparation for long jump take-off. Six male unilateral trans-femoral and seven male unilateral trans-tibial amputees competing in a World Championships final were filmed in the sagittal plane using a 100-Hz digital video camera positioned so that the last three strides to take-off were visible. After digitizing using a nine-segment model, a range of kinematic variables were computed to define technique characteristics. Both the trans-femoral and trans-tibial athletes appeared to achieve their reduction in centre of mass during the flight phase between strides, and did so mainly by extending the flight time by increasing stride length, achieved by a greater flexion of the hip joint of the touch-down leg. The trans-tibial athletes appeared to adopt a technique similar to that previously reported for able-bodied athletes. They lowered their centre of mass most on their second last stride (-1.6% of body height compared with -1.4% on the last stride) and used a flexed knee at take-off on the last stride, but they were less able to control their downward velocity at touch-down (-0.4 m x s(-1)). Both this and their restricted approach speed (8.9 m x s(-1) at touch-down), rather than technique limitations, influenced their jump performance. The trans-femoral athletes lowered their centre of mass most on the last stride (-2.3% of body height compared with -1.6% on the second last stride) and, as they were unable to flex their prosthetic knee sufficiently, achieved this by abducting their prosthetic leg during the support phase, which led to a large downward velocity at touch-down (-0.6 m x s(-1)). This, combined with their slower approach velocity (7.1 m x s(-1) at touch-down), restricted their performance.