Improved Breast Cancer Classification Through Combining Graph Convolutional Network and Convolutional Neural Network

AimIn a pilot study to improve detection of malignant lesions in breast mammograms, we aimed to develop a new method called BDR-CNN-GCN, combining two advanced neural networks: (i) graph convolutional network (GCN); and (ii) convolutional neural network (CNN).MethodWe utilised a standard 8-layer CNN, then integrated two improvement techniques: (i) batch normalization (BN) and (ii) dropout (DO). Finally, we utilized rank-based stochastic pooling (RSP) to substitute the traditional max pooling. This resulted in BDR-CNN, which is a combination of CNN, BN, DO, and RSP. This BDR-CNN was hybridized with a two-layer GCN, and yielded our BDR-CNN-GCN model which was then utilized for analysis of breast mammograms as a 14-way data augmentation method.ResultsAs proof of concept, we ran our BDR-CNN-GCN algorithm 10 times on the breast mini-MIAS dataset (containing 322 mammographic images), achieving a sensitivity of 96.20±2.90%, a specificity of 96.00±2.31% and an accuracy of 96.10±1.60%.ConclusionOur BDR-CNN-GCN showed improved performance compared to five proposed neural network models and 15 state-of-the-art breast cancer detection approaches, proving to be an effective method for data augmentation and improved detection of malignant breast masses.     

Evaluation of a Training Program in Aging Research for Social Work Faculty

Since 2004, we have offered a postgraduate training program in aging research for social work faculty from across the country. The overarching goal of the program is to expand the pool of social work faculty engaged in aging research. This, in turn, will reinvigorate participants' teaching; prepare them to update aging-related content in the curriculum, with special emphasis on cultural diversity and methodological issues; and enhance their ability to motivate new generations of students to pursue the study of aging. Program design includes an initial 8-day institute in Summer I; ongoing consultation, update meetings at several national conventions, and a 4-day midyear meeting during the intervening year; and a follow-up institute during Summer II. Between 2004 and 2009, seven cohorts of social work faculty (with 14–15 members in each cohort) participated in the program. More than 40 percent of the participants were from communities of color including African American, Hispanic American, Native American, and Asian American. This article reports the results of initial evaluation from two most recent cohorts (Cohort 6 and Cohort 7). In addition, it reports the results of a follow-up study we conducted in June 2010 on cohorts 1–5. Key lessons learned in offering the program are also shared.     

Learner support: The critical link in distance education

This study evaluates the OklahomaTelevised Instruction System, through an analysis of the student support services to include the resources available to the learner, the communications process characterized by the co‐ordination services provided among the on‐campus and distance sites, and the communication process characterized by the mechanical and electronic transfer of information. The study also compares the attitudes and performance of the participating on‐campus and distance students.     

Fabricating scaffolds by microfluidics

In this paper, we demonstrate for the first time the technique to using microfluidics to fabricate tissue engineering scaffolds with uniform pore sizes. We investigate both the bubble generation of the microfluidic device and the application of foam as a tissue engineering scaffold. Our microfluidic device consists of two concentric tapered channels, which are made by micropipettes. Nitrogen gas and aqueous alginate solution with Pluronic^® F127 surfactant are pumped through the inner and the outer channels, respectively. We observe rich dynamic patterns of bubbles encapsulated in the liquid droplets. The size of the bubble depends linearly on the gas pressure and inversely on the liquid flow rate. In addition, monodisperse bubbles self-assemble into crystalline structures. The liquid crystalline foams are further processed into open-cell solid foams. The novel foam gel was used as a scaffold to culture chondrocytes.     

Remedial education for high-risk university freshmen – the case of a university of technology in Taiwan

Potential high-risk freshmen for three core courses (BasicMath, Calculus, and Computing) in the university were identified based on the “College Students’ Adjustment Check List (CSACL)” data available with the Student Development Centre in the Office of Students’ Affairs of the university. The study demonstrates that to ameliorate the problem of unpreparedness of freshmen, to check failure rates, and efficient use of limited resources, an effective remedial system could be developed by the combined inputs from the Office of Students’ Affairs, Computer Centre, Academic Affairs, and the Institutional Research. Our study corroborates the findings of other researchers that gender, teacher, department, high school performance, enrolment channel, and loads during remedial course influence the learning outcome. Also, it was found that the use of multi-evaluation approaches in different enrolment channels can attain higher retention rates.     

Investigating the Alignment of Bhutanese Mathematics Teachers’ Planned Approaches Within the Context of a Reformed Curriculum

Reform of mathematics education has been in focus in many countries including those in major economic transition. This paper reports a segment of a study which was conducted in Bhutan, where a reformed elementary mathematics curriculum has been recently introduced. The reformed curriculum is based on social constructivism and its design has been influenced by the USA’s National Council of Teachers of Mathematics (NCTM) standards. This paper reports upon the planned teaching of a sample of elementary (primary) teachers in their implementation of the reformed curriculum. The data for this part of the investigation were aggregated from a qualitative survey of randomly selected elementary school teachers (N = 72) from 40 schools across the country. A set of 3 analytical rubrics, based on intentions embedded in the curriculum, was developed to analyse the alignment of teachers’ planned sample learning activities with the intentions of the curriculum. Our conclusions are that while the curriculum’s intentions might be meaningfully stated in the curriculum documents, implementation remains problematic because there appears to be a mis-alignment between curriculum intentions and classroom practices. For instance, teachers by not adopting evidence-based approaches recommended in the curriculum document and are continuing to deny students opportunities to achieve deep understanding in achieving national priorities. This paper also argues that the proposed analytical rubrics may be of value for Bhutanese mathematics educators and, with minor modification, educators in other contexts, as they critique planned and actual practices.     

Serum and platelet sialic acid in acute myocardial infarction

Blood samples from 39 patients with acute myocardial infarction and 15 healthy controls were analysed for serum and platelet sialic acid. Serum sialic acid levels in patients with acute myocardial infarction were significantly higher than controls (mean 2.7±0.46 μmol/ml Vs. 1.91±0.17 μmol/ml respectively). Levels of serum orosomucoid, an acute phase reactant, containing sialic acid, were also higher in these patients, suggesting a possible non-specific mechanism of increase in serum sialic acid concentration. In contrast, platelets contained significantly less sialic acid in patients with acute myocardial infarction than control (26.73±1.57 nmol/mg protein and 31.97±2.68 nmol/mg protein respectively).