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In 671 mother–child (49% male) pairs from an epidemiological birth cohort, we investigated (a) prospective associations between DNA methylation (at birth) and trajectories (ages 7–13) of oppositional defiant disorder (ODD), and the ODD subdimensions of irritable and headstrong; (b) common biological pathways, indexed by DNA methylation, between ODD trajectories and attention deficit hyperactivity disorder (ADHD); (c) genetic influence on DNA methylation; and (d) prenatal risk exposure associations. Methylome‐wide significant associations were identified for the ODD and headstrong, but not for irritable. Overlap analysis indicated biological correlates between ODD, headstrong, and ADHD. DNA methylation in ODD and headstrong was (to a degree) genetically influenced. DNA methylation associated with prenatal risk exposures of maternal anxiety (headstrong) and cigarette smoking (ODD and headstrong).  相似文献   
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This case study attempts to capture the way gender is constructed and experienced in the social world of the nursery school. It presents findings from a staff survey, structured and unstructured observations of one male’s and one female’s professional practice and one-to-one interviews with children aged three to four years. Despite practitioners’ reported intentions to challenge traditional notions of gender, construction of traditional gender distinctions was not problematised by staff and was upheld by comments of children. Children appeared to construct themselves in terms of gender stereotypes and were offered only limited alternative gender positions by the male and female practitioners.  相似文献   
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The current study examined associations between physical education (PE) class enjoyment and sociodemographic, personal, and perceived school environment factors among early adolescent girls. Participants included 1,511 sixth-grade girls who completed baseline assessments for the Trial of Activity in Adolescent Girls, with 50% indicating they enjoyed PE class a lot. Variables positively associated with PE class enjoyment included physical activity level, perceived benefits of physical activity, self-efficacy for leisure time physical activity, and perceived school climate for girls' physical activity as influenced by teachers, while body mass index was inversely associated with PE class enjoyment. After adjusting for all variables in the model, PE class enjoyment was significantly greater in Blacks than in Whites. In model testing, with mutual adjustment for all variables, self-efficacy was the strongest correlate of PE class enjoyment, followed by perceived benefits, race/ethnicity, and teachers' support for girls' physical activity, as compared to boys, at school. The overall model explained 11% of the variance in PE class enjoyment. Findings suggest that efforts to enhance girls' self-efficacy and perceived benefits and to provide a supportive PE class environment that promotes gender equality can potentially increase PE class enjoyment among young girls.  相似文献   
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While student parents now represent a significant proportion of the higher education population in England, this group has been given limited consideration in policy circles. Using a social constructivist and feminist theoretical framework, this paper draws on a research project investigating the role of higher education policies in supporting student parents in England. It focuses on findings from 40 interviews conducted with student parents enrolled on university programmes. It shows that, in the context of the default construction of the university student as carefree, student parents often describe their experience of navigating academia as a struggle, in which time-related, financial, health and emotional problems prevail. However, the stories they tell also emphasise the benefits associated with their dual status. By doing so, they resist the discourse of deficit typically applied to ‘non traditional’ students and produce a counter-discourse that disturbs the long-lived binary opposition between care and academia.  相似文献   
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