Replication,pathogenicity, and transmission of SARS-CoV-2 in minks

Minks are raised in many countries and have transmitted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to humans. However, the biologic properties of SARS-CoV-2 in minks are largely unknown. Here, we investigated and found that SARS-CoV-2 replicates efficiently in both the upper and lower respiratory tracts, and transmits efficiently in minks via respiratory droplets; pulmonary lesions caused by SARS-CoV-2 in minks are similar to those seen in humans with COVID-19. We further found that a spike protein-based subunit vaccine largely prevented SARS-CoV-2 replication and lung damage caused by SARS-CoV-2 infection in minks. Our study indicates that minks are a useful animal model for evaluating the efficacy of drugs or vaccines against COVID-19 and that vaccination is a potential strategy to prevent minks from transmitting SARS-CoV-2.     

基于表示学习的双层知识网络链路预测

当前,针对知识网络的链路预测主要是基于网络拓扑结构的相似性,很少考虑作者的研究领域,导致信息利用不充分等问题,因此本文提出了双层知识网络的链路预测框架hypernet2vec。双层知识网络,即作者合著关系网络和学术领域关系网络,利用网络表示学习,分别将两层网络中的节点映射到低维的向量空间,再输入到专门设计的卷积神经网络中计算并进行链路预测。与经典的链路预测指标如RA指标、LP指标和LRW指标等相比,hypernet2vec模型预测的AUC(area under curve)值取得了显著的提升,平均提升幅度达11.17%。文章还从情报产生层面和复杂系统层面,对模型发生作用的深层机理进行了探讨。     

谁在主导中日韩的国际科学合作?

[目的/意义]为了探究中日韩的国际科学合作中的主导地位及变化趋势。[方法/过程]以"中日"、"中韩"和"中日韩"国际论文合著现象为分析对象,通过科学计量的方法和手段,从重要作者、高影响力论文和资助者三个维度来分析近40年来中日韩科学合作背后的主导力量。[结果/结论]研究结果发现中日科学合作呈现出日本主导趋势由强到弱,而中国主导趋势渐强并超过日本;中韩科学合作呈现双方共同主导的特征;在三国合作中,中国主导的论文影响力较强,但随着论文影响力的增大,中国显示出的主导优势却在减弱;中国作为科研资助者极大地推动了三国的科学合作。     

网络嵌入、知识惯性与双元创新能力 ——基于动态视角的评述

[目的/意义]网络嵌入和知识惯性对提升企业创新能力具有重要影响。[方法/过程]通过文献分析,针对网络嵌入及其演化特征对知识惯性的影响、知识惯性对双元创新能力的影响以及网络嵌入对双元创新能力的影响进行了系统梳理和评述。[结果/结论]总结提炼了3点结论,并在此基础上就如何充分利用网络嵌入的演化特征来调节知识惯性与双元创新能力间的关系,从动态视角提出了整合性理论框架以及进一步的研究思路与展望,不仅对深化该领域的研究具有理论与方法启示,同时对我国企业在动态网络下有效整合网络嵌入和知识惯性、提升双元创新能力具有重要现实指导意义。     

问题教学的分析与实践

所谓问题教学,是指以问题为中心的教学,它是把教学内容化作问题,引导学生通过解决问题从而掌握知识、形成能力、养成心理品质的过程。它体现了以教师为主导,学生为主体的原则,有利于学生更好地掌握系统知识,提高探究能力。     

川江号子

川江号子,是四川各地通航河流、湖泊船工号子的统称,是船工、纤夫在长期推船、拉纤的艰苦劳动过程中,为了协调步伐,统一动作,鼓舞士气,激励劳动情绪,齐心合力,战胜险滩恶水,保障船只安全航行,在实践中创造的船工、纤夫劳动的歌.     

汉语词汇学训诂学研究的新创获——评胡继明教授新著《《广雅》研究》

<尔雅>的一部训诂学词汇学著作,在"雅学"中占有重要地位.自隋朝曹宪为之作音以后,历来受到训诂学家的重视.     

Cross-cultural influence on communication effectiveness and user interface design

The objective of this study was to investigate the impact of cultural diversity on communication effectiveness with different communication styles and to apply the results in the field of user interface design for computer-based communication systems. The scope of this study was limited to the relationship between context and verbal/nonverbal communication, and also the relationship between power distance and communication interaction. The results indicated that high context people (HCP) had better communication effectiveness in comprehending nonverbal clues than low context people (LCP), while LCP had better communication effectiveness in verbal communication than their counterparts. It was also found that high power distance people (HPDP) could not communicate as effectively as low power distance people (LPDP) during communication with interaction, but there was no significant difference between HPDP and LPDP in dealing with communication without interaction.     

作為物質文化的"中國現代文學"

作為學者,在公開場合發表演講有兩種策略,一是"小題大做",一是"大題小做".這有點像寫論文,必須先設定讀者:面對公眾發言,你得乾脆利落,越簡單明了越好,不能雲山霧罩,把聽眾繞糊塗了.     

Century-old Brand Offers Fresh Spring Tea

In the chill of the early spring in April, Wuyutai, a century-old tea shop served local customers of Beijing with fresh green tea picked and processed before the Pure Bright Festival. The well-picked and finely-processed green tea sold so well that it ran out of supply. Like what happened in previous years, the tea variety of Dragon Well from the West Lake is the most popular early spring tea among local customers. This tea variety is famous not for its super quality but also for its cultural richness.