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31.
    
The levels of norepinephrine (NE), dopamine (DA) serotonin (5-HT) and its metabolite 5-hydroxyindole acetic acid (5-HIAA) have been determined in the cerebrospinal fluid (CSF) of normal (n=25) and suicidal attempt cases (n=30). A significant decrease in the level of NE (p<0.01), 5-HT(p<0.001) and 5-HIAA (p<0.001) in the CSF of suicide attempt cases were observed as compared to normal controls. It is concluded that CSF 5-HIAA level which is drastically depleted may be used as an early biochemical indicator of suicidal attempt so that it may be treated by the drugs which can enhance the suppressed neurotransmitter activity.  相似文献   
32.
This paper explores the relationship among ICT infrastructure (i.e., computing devices and Internet), one-to-one computing program and student ICT activities in school. It also looks into the differences of how ICT is being used in the teaching of English, mathematics and science at the elementary school level in relation to the availability of computing devices, Internet connection and one-to-one program. A total of 360 Grade 5 students from three schools (120 students from each school) in the western part of Singapore participated in a questionnaire adapted from the Program for International Student Assessment (PISA) ICT Familiarity Component for Student Questionnaire regarding students’ ICT use. One of the participating schools has implemented a school-based one-to-one computing program for all its students for the past nine years, with the school providing the necessary computing devices for all its Grade 1 to 3 students and a student computer ownership program to encourage all its Grade 4 students to procure their own computing devices to be used till completion of elementary education at Grade 6. The regression analyses suggest that how ICT is being used plays a more significant role in predicting the frequency of ICT use for the various subject areas than ICT infrastructure and one-to-one computing program. Further analysis also reveals that one-to-one computing program and availability of computing devices have a significant interaction effect on the frequency of ICT usage for English but not for mathematics and science—the presence of computing devices seem to have an impact for the usage of ICT for English but not the other two subject areas. The findings concur with earlier studies that there are differences in frequency and how ICT is being used in the teaching of English, mathematics and science.  相似文献   
33.
Spatial understanding of complex anatomical concepts is often a challenge for learners, as well as for educators. It is even more challenging for students with low mental spatial abilities. There are many options to teach spatial relationships, ranging from simple models to high-end three-dimensional (3D) virtual reality tools. Using a randomized controlled trial design, this study explored the use of a unique combination of deictic and iconic hand gestures to enhance spatial anatomical understanding, coining the term “Air Anatomy”. The control group (n = 45) was given a lecture on the anatomy of extraocular muscles, while the intervention group (n = 49) received the same lecture including “Air Anatomy” hand gestures. When compared to the control group, the post-test scores for the intervention group were significantly higher for basic recall (P < 0.001; Mann–Whitney U test) and for the application of knowledge (P = 0.015; Mann–Whitney U test). Students with low to moderate spatial ability (as assessed by a mental rotation test) were found to benefit most by this technique. Students in the intervention group also reported a lower extrinsic cognitive load and higher germane load, when compared to the control group. An instructional skills questionnaire survey indicated the effectiveness of this technique in improving overall classroom experience. Feedback of the students in the intervention group was also favorable for instruction using “Air Anatomy”. The study suggests that “Air Anatomy” is a useful, “no-cost”, accessible method that aids spatial understanding of anatomical concepts.  相似文献   
34.
    
Confocal Raman microscopy is important for characterizing 2D materials, but its low throughput significantly hinders its applications. For metastable materials such as graphene oxide (GO), the low throughput is aggravated by the requirement of extremely low laser dose to avoid sample damage. Here we introduce algorithm-improved confocal Raman microscopy (ai-CRM), which increases the Raman scanning rate by one to two orders of magnitude with respect to state-of-the-art works for a variety of 2D materials. Meanwhile, GO can be imaged at a laser dose that is two to three orders of magnitude lower than previously reported, such that laser-induced variations of the material properties can be avoided. ai-CRM also enables fast and spatially resolved quantitative analysis, and is readily extended to 3D mapping of composite materials. Since ai-CRM is based on general mathematical principles, it is cost-effective, facile to implement and universally applicable to other hyperspectral imaging methods.  相似文献   
35.
研究目的:优化获得血红密孔菌(P.sanguineus)的最佳培养基组成,提高耐热漆酶的产量。创新要点:获得了目前文献报道的最高水平的漆酶活力。研究方法:通过单因素试验研究了不同培养基(番茄汁、麦麸、麦芽提取物和葡萄糖细菌蛋白胨培养基)和不同组合诱导剂(大豆油、阿魏酸、没食子酸、二甲基苯胺、酸性蓝62和活性蓝19分别与硫酸铜组合诱导剂)对P.sanguineus产耐热漆酶的影响。在此基础上采用中心组合试验设计,进一步研究了番茄汁培养基结合硫酸铜和大豆油组合诱导剂对P.sanguineus产耐热漆酶的影响。利用SAS10.0和响应面分析方法对试验结果进行了统计分析和建立回归模型。重要结论:通过中心组合设计优化得出P.sanguineus产耐热漆酶的最优培养基条件:以36.8%番茄汁为培养基,以3 mmol/L硫酸铜和1%大豆油作为组合诱导剂。该条件下在10 L搅拌槽生物反应器中漆酶活力达到了143 000 IU/L(2,2'-联氮双(3-乙基苯并噻唑啉-6-磺酸)为底物,pH值为3.0)。  相似文献   
36.
The cardiac sarcolemma was characterized in 13 normal and 11 ischemic dog hearts by enzyme analysis and compositional assays. Significant decreases in the activities of the sodium-potassium and calcium pumps and structural compositional disturbances were observed in ischemia. High concentrations of oleic acid, a fatty acid and palmitoyl carnitine, a fatty acid intermediate caused inhibition of the enzyme pump activities of the normal sarcolemma. Thus, ischemia results in the functional impairment of the sarcolemma. Accumulation of fatty acid and fatty acid intermediates, occurring in myocardial ischemia, could be an underlying mechanism.  相似文献   
37.
Apolipoprotein E genotypes and lipid and lipoprotein levels were determined in hypercholesterolemic and angiographically vertified CHD subjects and compared against 90 normolipidemic controls. The ε4 allele was significantly prevalent in the hypercholesterolemic and CHD subjects. Significant increase in total cholesterol levels in apo ε4 containing subjects were observed in the hypercholesterolemic and CHD group. The study suggests that the ε4 allele by influencing the lipid levels could act as a risk factor for CHD.  相似文献   
38.
    
As part of a major study of classroom environment conducted by the International Association for the Evaluation of Educational Achievement (IEA), primary and secondary teachers were asked the degree of responsibility they felt for various aspects of their teaching, such as the content and the way they taught, assessment practices, student progress and interactions with parents.The countries involved in the study were Australia, Canada (Ontario and Quebec), Hungary, Israel, the Netherlands, Nigeria, the Republic of Korea, and Thailand. When considered as a total group, the highest proportions of teachers felt responsible for the amount of homework set, followed by classroom organization and use made of tests. Less than half the teachers felt responsible for deciding on student progress and only a quarter for the topics they taught.When comparisons were made across countries, most teachers in Israel, Australia and Ontario, about half the teachers in Quebec, Nigeria and the Republic of Korea, and minorities of teachers in Hungary, the Netherlands and Thailand felt generally responsible. Possible links between teacher responsibility and professionalism are suggested.
Zusammenfassung Primar- und Sekundarlehrer wurden im Rahmen einer von der International Association for the Evaluation of Educational Achievement (IEA) durchgeführten größeren Studie betreffs der Gestaltung des Klassenzimmers über den Grad der Verantwortung, den sie für verschiedene Aspekte ihrer Lehrtätigkeit empfanden, befragt; so z. B. über Inhalt und Art des Lehrens, Bewertungspraktiken, Fortschritt der Schüler und wechselseitigen Einfluß mit den Eltern.Die in die Studie einbezogenen Länder waren Australien, Kanada (Ontario und Québec), Ungarn, Israel, die Niederlande, Nigeria, Südkorea und Thailand. Der größte Teil der Lehrer, als Gesamtgruppe betrachtet, fühlte sich für die Menge der gestellten Hausaufgaben verantwortlich, gefolgt von der Einrichtung des Klassenzimmers und der Durchführung von Klassenarbeiten; weniger als die Hälfte der Lehrer fühlte sich für die Beurteilung des Fortschritts der Schüler verantwortlich und nur ein Viertel für die von ihnen unterrichteten Themen.Bei Ländervergleichen stellte sich heraus, daß sich die meisten Lehrer in Israel, Australien und Ontario, ungefähr die Hälfte der Lehrer in Québec, Nigeria und Südkorea und nur wenige Lehrer in Ungarn, den Niederlanden und Thailand allgemein verantwortlich fühlten. Es werden mögliche Verbindungen zwischen Verantwortlichkeit der Lehrer und Professionalismus angedeutet.

Résumé Dans le cadre d'une étude majeure du milieu scolaire conduite par l'Association internationale de l'évaluation des résultats scolaires (IEA), on a demandé aux enseignants du primaire et du secondaire quel est le degré de responsabilité qu'ils éprouvent á l'égard des divers aspects de leur travail, tels que le contenu et la méthodologie qu'ils emploient, les techniques d'évaluation, la progression des apprenants et les interactions avec les parents.Les pays impliqués dans cette étude étaient l'Australie, le Canada (Ontario et Québec), la Hongrie, Israel, les Pays-Bas, Le Nigeria, la République de Corée et la Thailande. Considérés comme un groupe entier, la majorité des enseignants se sentaient responsables de la quantité de devoirs à faire à la maison, puis de l'organisation de la classe et enfin de l'utilisation faite des tests. Moins de la moitié des enseignants se sentaient responsables de la décision de la progression des élèves et seul un quart des maltres disaient être responsables des thèmes qu'ils enseignaient.Les comparaisons faites entre les pays ont révélé que la plupart des enseignants en Israel, en Australie et dans l'Ontario, environ la moitié des maltres au Québec, au Nigeria et en République de Corée, et quelques groupes insignifiants en Hongrie, aux Pays-Bas et en Thailande se sentaient responsables généralement. On mentionne ensuite les liens qui peuvent éventuellement être établis entre la responsabilité et le professionnalisme de l'enseignant.
  相似文献   
39.
A number of terms have been used to describe knowledge needed for teaching, one of which is subject knowledge. How knowledge for teaching is conceptualised in teacher education prioritises some knowledge bases over other knowledge bases. Further, knowledge prioritised by student teachers is influenced by socialisation prior to and during an initial teacher education course and priorities for student teachers as they develop as teachers. Previous research in physical education teacher education points to the pre-eminence of content knowledge above other knowledge bases. The purpose of this study was to look at what knowledge is prioritised by student teachers, school-based mentors and university tutors working on three secondary physical education initial teacher education courses in England. Results showed that content knowledge was seen as having greater importance for student teachers and mentors, but university tutors generally conceptualised subject knowledge more broadly, suggesting that it should be seen as covering a number of knowledge bases needed for teaching. These results are discussed in relation to socialisation processes in education and phases of development. Although there is a clear physical education focus to this work, it is possible that student teachers learning to teach other subjects may also focus excessively on subject content knowledge above other knowledge bases.  相似文献   
40.
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