Modulation of an activity response with associative and nonassociative fear in the rat: A lighting differential influences the form of defensive behavior evoked after fear conditioning

Rats confronted with the onset of a light gradient display a transient increase in locomotion called theactivity response (AR) and a dark preference (Godsil & Fanselow, 2004). These experiments demonstrate that the magnitude of the AR can be blunted with Pavlovian fear-conditioning procedures via associative and nonassociative fear. Although manifested in decreased locomotion, the blunted AR effect was not due to increased freezing or immobility behaviors. Instead, rats displayed reduced rearing and an increase in a class of behaviors calledstationary activity. These results suggest that the lighting differential supplied by the cue influences the topography of defensive behavior and reduces the expression of freezing. This procedure provides a means by which to examine learned and unlearned defensive responses to the same stimulus.     

陕西省竞技武术套路发展问题研究

从陕西省竞技武术套路发展的现状入手,采用文献资料法、特尔菲（DELLPHI）法、逻辑分析法等研究方法,以陕西省武术队伍及训练工作的教练员、裁判员、运动员为研究对象,通过剖析现今中国竞技武术套路的技术水平、模式、培养体制的基础上,对陕西省武术发展现状进行分析,并提出针对陕西省竞技武术套路发展的相应对策。     

产业集群结构、适应能力与升级路径研究

产业集群生存与发展能力主要取决于自身结构,而集群结构主要包括企业集聚结构和支撑结构。本文通过设计大企业集中度、集群品牌、专业市场、公共科技平台和行业协会等指标度量集群结构指数,根据对浙江省产值超50亿元的112个集群的数据收集与分析,划分产业集群为四种类型。结果显示,目前绝大数集群是处于大企业集中度低、支撑结构不完善的块状经济形态。同时,通过设计集群生存能力、发展能力与适应能力的指标体系,并选择样本中四个典型集群进行统计分析。结果表明,集群结构与生存能力、发展能力和适应能力存在显著正相关,即,随着集群的大企业集中度提高和综合支撑体系完善,集群的适应能力上升。进一步解剖四个典型集群的结构动态升级过程,找到了集群升级的三条路径,为政策制定者提供了理论支撑。     

应急管理:社会管理的核心功能

当今世界,自然灾害、气候变化、环境污染、能源危机、资源短缺、群体间各类冲突等都可能引起影响深远的突发事件,消耗大量的社会资源,从而影响经济发展和社会进步。笔者认为,风险防范与突发事件应急管理是和平时期政府所具备的公共管理3大职能之一,且在现代社会中的作用将越来越突出。近年来随着我国社会的快速发展,社会内部的诸多矛盾不断涌现,经触发而以突发事件的形式出现的频率越来越高,政府该如何应对?如何借助更为科学合理的应急管理维护社会稳定、促进社会发展,并在国际上树立威望?本文将就这些问题展开探讨。     

Study of C-Reactive Protein and Myocardial Infarction in the Indian Population

To analyse the association of high sensitivity C-reactive (hsCRP) protein levels and −717A/G single nucleotide polymorphism of CRP with acute myocardial infarction (AMI) in the Indian population. Study population included 100 MI cases wherein 32 patients had experienced previous MI (MI-Group-1), 68 MI cases were recruited at presentation (MI-Group-2) and equal number of age and gender matched healthy individuals. hsCRP levels were determined by ELISA and genotyping of −717A/G was carried out by polymerase chain reaction-based restriction digestion method. The −717A/G genotypes did not influence hsCRP level and their distribution did not differ between groups. However, in the present study hsCRP demonstrated significant correlation with BMI in controls of both the genders and with triglycerides in females of AMI at presentation who otherwise are with low risk profile. Identifying traditional risk factors associated with inflammation may help in controlling the acute event.     

A Comparative Study of Bone Scan Findings and Serum Levels of Tumor Marker CA15-3 in Patients with Breast Carcinoma

Breast cancer is one of the most frequent malignancies in the world. Available staging procedures to detect breast cancer are bone scan, chest X-ray, liver ultrasonography, computerized tomography, estimation of tumor markers like carbohydrate antigen (CA15-3) and carcino embryonic antigen. These procedures are expensive and may not be required in all cases. Out of 70 patients studied, 55 had normal CA15-3 and 15 had elevated levels of Ca15-3. Eight (14.5%) of the 55 patients with normal CA15-3 had abnormal bone scan. Fifteen patients had CA15-3 levels above the normal range and among these 9 (60%) had abnormal bone scan. While prime facie it would appear that a high level of CA15-3 correlate with abnormal bone scan, it is also true that the numbers are small at present and conclusions about the validity of CA15-3 as marker of bone metastasis may be premature.     

集群数据库系统多指标动态负载均衡方法的设计与实现

负载均衡是提高数据库集群系统整体性能的重要技术手段之一,其核心在于如何对实际到达的任务进行合理的动态分配.在对比分析现有数据库集群系统的负载均衡方法的基础上,提出一种新的多指标动态负载均衡方法.该方法对后端数据库节点的多个性能指标进行采样,使用多指标决策方法TOPSIS计算各个节点负载情况,用负载最轻的节点作为决策结果.实验结果表明:与传统负载均衡方法比较,该方法可显著提高集群数据库系统的整体性能.