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441.
How can schools as learning organisations support the realisation of a new curriculum's aspirations? This article describes four common and interrelated challenges—depth, spread, reach, and pace—associated with enacting a new curriculum. It then argues that curriculum capital represented by schools and practitioners that address these challenges and meet associated learning demands—commitment, knowledge, understanding and capability—is essential to ensure that curriculum aspirations are realised. We propose that schools that are learning organisations create the kinds of conditions necessary for responding to the challenges and learning demands. In such schools the considerable individual, collaborative and collective learning needed at many levels is recognised. We highlight how each of the four challenges might be addressed by seven dimensions and four transversals of schools as learning organisations, while recognising that task will be more feasible in systems that are also learning and providing supportive conditions.  相似文献   
442.
Conceptualisations of the self in relation to others are examined among a group of young women attending a fee‐paying school in England. As part of a larger study exploring intimacy and agency among young women from relatively privileged class backgrounds, 54 young women participated in focus group discussions and interviews. Findings reveal that young women strongly positioned themselves in relation to ‘others’ – both those they saw as ‘chavs’ and young people attending state schools. Yet, just as often, these young women sought to distinguish themselves from other private school peers. Within the privileged bubble the young women inhabited, locations within the wider private school network, type and extent of parental wealth, and fame were all markers used to differentiate the self from others.  相似文献   
443.
Agency among young women is often understood as fleeting in nature, and studies rarely offer insights into how agency could become a more sustained position. Using data from 54 young women discussing their sexual and intimate relationships, this paper suggests a new way of understanding agency beyond that found in work which stresses agentic practice as resistance or the challenging of dominant expectations and understandings. Instead, through the notion of ‘agency in action’ we begin with young women’s conceptualisations of power. In this study, power was viewed as a resource that is shared between partners, but also a capacity of the self. These conceptualisations offer two new ways of understanding agency in intimate relations – either through ‘reacting into action’ and taking power back; or by ‘starting from’ a powerful position. Central to an understanding of young women’s agency is the role of emotions and recognition of these as motivators for change.  相似文献   
444.
Chaos in the home is a key environment in cognitive and behavioral development. However, we show that children's experience of home chaos is partly genetically mediated. We assessed children's perceptions of household chaos at ages 9 and 12 in 2337 pairs of twins. Using child-specific reports allowed us to use structural equation modeling to explore the genetic and environmental etiology of children's perceptions of chaos. We found that these perceptions are significantly heritable (22%), with the remainder explained by environmental influences. Finding that genes influence children's experience of chaotic environments has far-reaching implications for how we conceptualize the family home and its impact on cognitive and behavioral development.  相似文献   
445.
This paper reports on the first stage of an investigation into monitoring and evaluating the impact of information management (IM) within a local government context. The overall study will utilise a combination of principles from various results-based, outcomes-based and social change approaches (Logical Framework Analysis, Most Significant Change, and Outcomes Mapping) in an attempt to move Leicestershire County Council away from a culture focused on traditional performance measurement, i.e. percentage change in use of services provided to the public, to something of real value. Interviews with 20 senior managers highlighted the important IM issues for Leicestershire County Council as a local government. These initial findings showed that maintaining high quality, trusted, and governed information and knowledge resources were of great value to the organisation. Analysis showed that 85% of senior managers interviewed considered IM to be “critical” in the achievement of organisational outcomes. Further analysis enabled the development of an initial framework indicating key areas where IM can have impact. These key areas will become the focus of further research, where applying a combination of approaches aforementioned will define the boundary partners, their specific outcomes and progress markers with possible impacts proposed. This detail will help to develop a framework for measuring the impact of IM.  相似文献   
446.
The purpose of this study is to find out the frequency of TP53 mutations in acute myeloid leukemia (AML) patients and correlate sensitivity of drug response with TP53 mutations. In AML more than 90 % of cases comprise of wild type TP53. 94.2 % of TP53 mutations are found within exon 5–8 of which 73 % are point mutations. TP53 mutations were analysed with high resolution melting curve analysis. We analysed 106 AML samples of which we found nine mutations which represents 8.5 % mutation rate and found one rare SNP. The effect of TP53 mutations were studied on the chemosensitivity of two new drugs AZD115 and RHPS4, an Aurora Kinase B inhibitor and Telomerase inhibitor respectively. Four mutations were found out of 17 for RHPS4 stating significant (p = 0.002) increase in sensitivity and no mutation found in AZD1152 database, but need more study to get definite conclusion.  相似文献   
447.
This paper reports on observational approaches developed within a UK study to the identification and assessment of metacognition and self-regulation in young children in the 3–5 year age range. It is argued that the development of observational tools, although containing methodological difficulties, allows us to make more valid assessments of children’s metacognitive and self-regulatory abilities in this age group. The analysis of 582 metacognitive or self-regulatory videotaped ‘events’ is described, including the development of a coding framework identifying verbal and non-verbal indicators. The construction of an observational instrument, the Children’s Independent Learning Development (CHILD 3–5) checklist, is also reported together with evidence of the reliability with which it can be used by classroom teachers and early indications of its external validity as a measure of metacognition and self-regulation in young children. Given the educational significance of children’s development of metacognitive and self-regulatory skills, it is argued that the development of such an instrument is potentially highly beneficial. The establishment of the metacognitive and self-regulatory capabilities of young children by means of the kinds of observational tools developed within this study also has clear and significant implications for models and theories of metacognition and self-regulation. The paper concludes with a discussion of these implications.
David WhitebreadEmail:
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448.
449.
This article investigates the error rates in shelf-ready cataloged monographs from Ingram Coutts Information Services that were received at The University of Western Ontario. Using quality control reports from a period of two years, over 500 cataloging errors were entered into a database organized by frequency, severity, and other factors. With this information, we analyzed the frequency of errors and their root causes. We found that overall error rates are low, and the quality of shelf-ready cataloging has improved since first implementing the outsourcing program.  相似文献   
450.
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