Effects of moniliformin and selenium on human articular cartilage metabolism and their potential relationships to the pathogenesis of Kashin-Beck disease

Objective:To investigate the effects of mycotoxin moniliformin (MON) on the metabolism of aggrecan and type II collagen in human chondrocytes in vitro and the relationship between MON and Kashin-Beck disease (KBD).Methods:Human chondrocytes were isolated and cultured on bone matrix gelatin to form an artificial cartilage model in vitro with or without MON toxin.Cell viability was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay.The expression of aggrecan and type II col...     

Impacts of directed tutorial activities in computer conferencing: a case study

This paper describes a qualitative study of asynchronous electronic conferencing by three tutorial groups on the same postgraduate course (Teaching English to Speakers of Other Languages Worldwide), forming part of an MA in Applied Linguistics (via Distance Education) at the Open University, UK. The groups varied in the degree to which the tutor participated in the discussion and in whether the tutor's input took the form of responding to student posts or the setting of tasks to scaffold the learners' development of academic skills. It is argued that the least interventionist strategy in terms of tutor response and task-setting resulted in the least productive conference discussion in terms of both communicative interaction and academic development, while a more interventionist role by the tutor depended for its success on characteristics of the tutor input and the task set.     

Teaching Literacy through Braille in Mainstream Settings whilst Promoting Inclusion: Reflections on Our Practice

We would describe teaching literacy through braille as one of the most rewarding and challenging aspects of the role of a Qualified Teacher for the Visually Impaired (QTVI). This article focuses on teaching literacy through braille in mainstream settings whilst promoting inclusion and meeting the social–emotional needs of children who use braille. It aims to share good practice and is based on reflections from our own practice and research carried out by some of the authors. The article considers the impact of vision impairment on opportunities for literacy development, the main challenges QTVIs working in a peripatetic (itinerary) way face, as well as what works well and how we can overcome these challenges. The article describes what characterises good practice in teaching braille, describes effective collaborative work between teachers, other professionals and parents, and analyses how to promote inclusion whilst ensuring pupils access the specialist curriculum and individualised instruction.     

Validation of a brief measure of teachers’ perceptions of school climate: relations to student achievement and suspensions

Based on theory and research on learning environments, the Delaware School Climate Survey–Teacher/Staff (DSCS–T/S) was developed to provide schools with a brief, psychometrically sound measure of teachers’ perceptions of school climate. Multigroup confirmatory factor analyses, conducted on a sample of 5,781 teachers, support staff, administrators and other staff in 132 schools, showed that a bifactor model consisting of seven specific factors best represented the data. Those factors were Teacher–Student Relations, Student–Student Relations, Teacher–Home Communication, Respect for Diversity, School Safety, Fairness of Rules, and Clarity of Expectations. Measurement invariance was found across grade levels (i.e., elementary, middle, and high schools) and subgroups of respondents (i.e., teachers, instructional support staff and noninstructional staff). As evidence of concurrent validity across grade levels, nearly all scores, aggregated at the school level and correlated significantly and negatively with suspensions/expulsion rates and positively with academic achievement. The DSCS–T/S is likely to be useful to schools interested in assessing school climate and the effects of various programs, such bullying prevention programs, that target the seven dimensions of school climate measured.     

For the Honour of the School: Class in the Girls’ School Story

This article explores the constructions of class in British girls’ school stories. Feminist scholarship has, to some extent, reclaimed the school story, pointing to the widening of acceptable gender roles for female characters in girls’ school stories, compared to their counterparts in mixed-gender stories, and indeed real life. While the limitations of this middle/upper class milieu have been noted, they are less often explored. I use readings of Bourdieu as applied to femininities by scholars such as McRobbie and Skeggs to examine how the lived experience of class can trouble the status quo. School stories often limit encounters with working-class characters to servants, recipients of patronage or straightforward threats. However, in Brent-Dyer’s A Problem for the Chalet School (1956) a working-class character enters the school on her own terms. Her presence sparks the reaffirmation of the expectations for successful upper-class femininity.     

Transforming the twenty-first-century campus to enhance the net-generation student learning experience: using evidence-based design to determine what works and why in virtual/physical teaching spaces

The twenty-first century has seen the rapid emergence of wireless broadband and mobile communications devices which are inexorably changing the way people communicate, collaborate, create and transfer knowledge. Yet many higher education campus learning environments were designed and built in the nineteenth and twentieth centuries prior to wireless broadband networks. Now, new learning environments are being re-engineered to meet these emerging technologies with significant challenges to existing pedagogical practices. However, these next generation learning environments (NGLEs) have not been evaluated thoroughly to see if they actually work as they are scaled up across the higher education system. Whilst there have been a range of NGLEs designed globally – with Australia leading in the past five years or so – it is timely that a more rigorous research methodology drawing from health facility evidence-based design is taken to evaluate their effectiveness in improving the student experience and learning outcomes.     

Teachers' care in higher education: contesting gendered constructions

There is little research on care in higher education, and yet for many of those who teach in higher education institutions, care is an important part of their work. Care in the compulsory education sector has traditionally been linked to the feminine, and this paper considers whether this is also the case in higher education. It investigates how care is conceptualised and gendered in the literature and in narratives of teaching staff from New Zealand universities. It finds that there is much more to care than traditional models offer, and shows how this complexity of care challenges gendered stereotypes. It concludes that a broader understanding of care can help break the link to the feminine and acknowledge the value of care in higher education and beyond.