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Vincent Labrot Michael Schindler Pierre Guillot Annie Colin Mathieu Joanicot 《Biomicrofluidics》2009,3(1)
The overall traffic of droplets in a network of microfluidic channels is strongly influenced by the liquid properties of the moving droplets. In particular, the effective hydrodynamic resistance of individual droplets plays a key role in their global behavior. Here we propose two simple and low-cost experimental methods for measuring this parameter by analyzing the dynamics of a regular sequence of droplets injected into an “asymmetric loop” network. The choice of a droplet taking either route through the loop is influenced by the presence of previous droplets that modulate the hydrodynamic resistance of the branches they are sitting in. We propose to extract the effective resistance of a droplet from easily observable time series, namely, from the choices the droplets make at junctions and from the interdroplet distances. This becomes possible when utilizing a recently proposed theoretical model based on a number of simplifying assumptions. Here we present several sets of measurements of the hydrodynamic resistance of droplets, expressed in terms of a “resistance length.” The aim is twofold: (1) to reveal its dependence on a number of parameters, such as the viscosity, the volume of droplets, their velocity as well as the spacing between them. At the same time (2), by using a standard measurement technique, we compare the limitations of the proposed methods. As an important result of this comparison, we obtain the range of validity of the simplifying assumptions made in the theoretical model. 相似文献
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Hamilton A Wheeler QD 《Isis; an international review devoted to the history of science and its cultural influences》2008,99(2):331-340
The history of science often has difficulty connecting with science at the lab-bench level, raising questions about the value of history of science for science. This essay offers a case study from taxonomy in which lessons learned about particular failings of numerical taxonomy (phenetics) in the second half of the twentieth century bear on the new movement toward DNA barcoding. In particular, it argues that an unwillingness to deal with messy theoretical questions in both cases leads to important problems in the theory and practice of identifying taxa. This argument makes use of scientific and historical considerations in a way that the authors hope leads to convincing conclusions about the history of taxonomy as well as about its present practice. 相似文献
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The aims of this study were to compare the physiological and anthropometric characteristics of successful mountain bikers and professional road cyclists and to re-examine the power-to-weight characteristics of internationally competitive mountain bikers. Internationally competitive cyclists (seven mountain bikers and seven road cyclists) completed the following tests: anthropometric measurements, an incremental cycle ergometer test and a 30 min laboratory time-trial. The mountain bikers were lighter (65.3+/-6.5 vs 74.7+/-3.8 kg, P= 0.01; mean +/- s) and leaner than the road cyclists (sum of seven skinfolds: 33.9+/-5.7 vs 44.5+/-10.8 mm, P = 0.04). The mountain bikers produced higher power outputs relative to body mass at maximal exercise (6.3+/-0.5 vs 5.8+/-0.3 W x kg(-1), P= 0.03), at the lactate threshold (5.2+/-0.6 vs 4.7+/-0.3 W x kg(-1), P= 0.048) and during the 30 min time-trial (5.5+/-0.5 vs 4.9+/-0.3 W x kg(-1), P = 0.02). Similarly, peak oxygen uptake relative tobody mass was higher in the mountain bikers (78.3+/-4.4 vs 73.0+/-3.4 ml x kg(-1) x min(-1), P = 0.03). The results indicate that high power-to-weight characteristics are important for success in mountain biking. The mountain bikers possessed similar anthropometric and physiological characteristics to previously studied road cycling uphill specialists. 相似文献
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