Adaptive fuzzy tracking control for switched uncertain strict-feedback nonlinear systems

This paper concerns an adaptive fuzzy tracking control problem for a class of switched uncertain nonlinear systems in strict-feedback form via the modified backstepping technique. The unknown nonlinear functions are approximated by the generalized fuzzy hyperbolic model (GFHM). It is shown that if the designed parameters in the controller and adaptive laws are appropriately selected, then all closed-loop signals are bounded and the stability of the system can be kept under average dwell time methods. In the end, simulation studies are presented to illustrate the effectiveness of the proposed method.     

An integrated, multiparametric flow cytometry chip using "microfluidic drifting" based three-dimensional hydrodynamic focusing

In this work, we demonstrate an integrated, single-layer, miniature flow cytometry device that is capable of multi-parametric particle analysis. The device integrates both particle focusing and detection components on-chip, including a "microfluidic drifting" based three-dimensional (3D) hydrodynamic focusing component and a series of optical fibers integrated into the microfluidic architecture to facilitate on-chip detection. With this design, multiple optical signals (i.e., forward scatter, side scatter, and fluorescence) from individual particles can be simultaneously detected. Experimental results indicate that the performance of our flow cytometry chip is comparable to its bulky, expensive desktop counterpart. The integration of on-chip 3D particle focusing with on-chip multi-parametric optical detection in a single-layer, mass-producible microfluidic device presents a major step towards low-cost flow cytometry chips for point-of-care clinical diagnostics.     

Tracking controller design for random nonlinear benchmark system

This paper considers a benchmark system consisting of a rolling ball and a moving car in the oscillating surroundings. By using the Lagrange law, the dynamic model without disturbance is first constructed, then according to the relative motion principle, random oscillation of surroundings is transformed into the random noises in the constructed Lagrange equation. The special structure of the quasi-lower triangle of Lagrange equation motivates us to pay more attention to the vectorial backstepping technique. By selecting an appropriate Lyapunov-like function, a tracking controller with tunable parameters is designed such that all signals of the closed-loop system are bounded and track error can be made arbitrarily small.     

中原城市群产业技术扩散机制与创新协同效应研究

为促进和发挥中原城市群创新协同效应,打造高水平城市群,基于产业复杂网络视角提出赋权区域产业技术流树(RITFT)模型,并基于RITFT对中原地区的产业技术扩散结构机制与创新协同效应进行研究.首先提出区域产业技术相关度测量系数,在产业技术流网络(ITFN)基础上提出RITFT建模原理及方法,构建中原地区RITFT,并从干流、支流等产业技术流分布特征上揭示中原城市群产业技术创新与扩散的核心结构机制;进一步基于对个体产业承载、中介与扩散的基础效应和技术外溢、吸收强度与乘数效应等方面的分析,对中原城市群创新协同效应进行评价.研究发现:中原城市整体技术扩散协作效率较高,产业创新存在省内大协同、区域内小协同及空间支撑互补性强等特征.最后提出中原城市群应不断强化区域创新政策供给、完善产业协同创新体系,以综合科技服务平台为支撑建立新型的产业创新治理体系,打造区域高效的创新生态系统.     

高职院校应用化工技术专业学生职业素质教育探讨

本文主要对高职院校应用化工技术专业职业素质内容和实施方法进行了探讨,通过改革教学方法、课程考核体系等措施,提高了学生的职业素质,促进了职业教育的不断发展。     

Engineering G-quadruplex aptamer to modulate its binding specificity

The use of aptamers in bioanalytical and biomedical applications exploits their ability to recognize cell surface protein receptors. Targeted therapeutics and theranostics come to mind in this regard. However, protein receptors occur on both cancer and normal cells; as such, aptamers are now taxed with identifying high vs. low levels of protein expression. Inspired by the flexible template mechanism and elegant control of natural nucleic acid-based structures, we report an allosteric regulation strategy for constructing a structure-switching aptamer for enhanced target cell recognition by engineering aptamers with DNA intercalated motifs (i-motifs) responsive to the microenvironment, such as pH. Structure-switching sensitivity can be readily tuned by manipulating i-motif sequences. However, structure-switching sensitivity is difficult to estimate, making it equally difficult to effectively screen modified aptamers with the desired sensitivity. To address this problem, we selected a fluorescent probe capable of detecting G-quadruplex in complicated biological media.     

MES技术发展及应用研究

本文主要就制造执行系统(HES)的发展及其在企业系统中的应用进行了详细介绍.阐述了MES在企业系统中的位置、功能、作用以及MES给企业系统带来的益处和软件系统特征.最后展望了MES的发展趋势.     

浅析虚拟机技术在操作系统实践教学中的应用

针对目前很难在操作系统课程实践教学中开展多平台操作系统实验的情况,提出了利用虚拟机软件实现在一台普通计算机上同时运行多个操作系统方法,不但挖掘了现有教学实验设备的潜力,而且加强了学生对操作系统课程的综合应用能力,并增加了学生的实践动手机会。     

面向ERP实施的知识流管理

ERP实施是项漫长的系统工程,ERP在企业的实施能否成功,与实施企业、系统提供商、系统集成商、咨询公司等参与各方的协作密切相关。从知识管理角度出发,以解决ERP实施过程中知识缺口、知识壁垒等问题为目的,首先将ERP实施中的知识进行分类,然后在对ERP实施中知识流进行分析的基础上,建立了知识流模型,并就ERP实施中知识流管理的开展进行了分析。     

搜索引擎系统中的Web个性化信息推荐技术

Web个性化推荐技术在现代互联网中有着广泛的应用,它能将Web网络信息按照用户的个性化需求主动地向用户提供服务。但是由于现代搜索引擎通常缺乏用户的相关登录信息和网页访问路径信息,所以传统的Web个性化推荐服务并不完全适用于搜索引擎。由于用户在访问搜索引擎时会产生大量的关键词访问序列,而这种关键词访问序列蕴含着丰富的用户个性化信息,基于此,提出了一种利用搜索引擎访问日志中的关键词访问序列来进行Web个性化推荐服务的方法,并分析了相关技术特点和实现细节。