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Non‐cognitive dispositions have recently become psychological constructs of interest in the education, economics, philosophy, sociology, and psychology literature. In this article, I draw the distinction between property‐first and measurement‐first approaches to understanding the meaning of a particular non‐cognitive disposition theoretical term, ‘grit’, as well as the relationship between this term and its corresponding measurement procedure. I argue that, depending on which approach one takes, one is confronted with different norms for judging the success of any disposition‐measurement procedure pair, meaning that the difference in philosophical approaches may have practical import. I argue that the measurement‐first approach is the one educators and educational policy‐makers ought to adopt towards grit as it is less likely to lead to over‐valuing grit in situations where a gritty disposition may be harmful, better respects scientific virtues and values, and provides a clearer understanding of grit than the property‐first approach.  相似文献   
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The Human Brain Project (HBP) is a massive interdisciplinary project involving hundreds of researchers across more than eighty institutions that seeks to leverage cutting edge information and communication technologies to create a multi-level brain simulation platform (BSP). My worry is that some brain models running on the BSP will be persons. If this is right then not only will the in silico experiments the HBP envisions being carried on the BSP be unethical the mere termination of certain brain models running on the BSP will be unethical. To assess the possible personhood of certain brain simulations I consider John Searle’s critique of strong AI. In arguing that Searle’s critique fails I conclude that the HBP must tread carefully and devise strict rules on how research using the BSP ought to proceed.  相似文献   
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Constituting ~40% of body mass, skeletal muscle has essential locomotory and metabolic functions. As such, an insight into the control of muscle mass is of great importance for maintaining health and quality-of-life into older age, under conditions of cachectic disease and with rehabilitation. In healthy weight-bearing individuals, muscle mass is maintained by the equilibrium between muscle protein synthesis (MPS) and muscle protein breakdown; when this balance tips in favour of MPS hypertrophy occurs. Despite considerable research into pharmacological/nutraceutical interventions, resistance exercise training (RE-T) remains the most potent stimulator of MPS and hypertrophy (in the majority of individuals). However, the mechanism(s) and time course of hypertrophic responses to RE-T remain poorly understood. We would suggest that available data are very much in favour of the notion that the majority of hypertrophy occurs in the early phases of RE-T (though still controversial to some) and that, for the most part, continued gains are hard to come by. Whilst the mechanisms of muscle hypertrophy represent the culmination of mechanical, auto/paracrine and endocrine events, the measurement of MPS remains a cornerstone for understanding the control of hypertrophy – mainly because it is the underlying driving force behind skeletal muscle hypertrophy. Development of sophisticated isotopic techniques (i.e. deuterium oxide) that lend to longer term insight into the control of hypertrophy by sustained RE-T will be paramount in providing insights into the metabolic and temporal regulation of hypertrophy. Such technologies will have broad application in muscle mass intervention for both athletes and for mitigating disease/age-related cachexia and sarcopenia, alike.  相似文献   
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Postural Sway of Human Infants while Standing in Light and Dark   总被引:3,自引:0,他引:3  
Postural sway was measured in 12-14-month-old human infants and in adults while they were standing in the light and dark. Spectral density analyses conducted on all frequencies, at specific frequencies, and for individual subjects showed that infants generally did not sway significantly more in the dark than in the light, whereas adults did. For example, infants' dark/light sway proportions were 1.12 and 1.21 for the anterior-posterior and lateral dimensions, respectively, compared to adult values of 2.23 and 3.43 for one-footed stance, and 1.43 and 2.13 for two-footed stance. A statistical power analysis indicated that if the dark/light proportions for infants had been comparable to those for adults, significant differences could have been detected. These findings indicate that the early regulation of standing posture does not depend on the continuous availability of visual information.  相似文献   
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