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171.
Tim Lee 《British Journal of Special Education》1991,18(3):100-102
How LEAs are measuring and allocating resources for special educational needs varies widely. Yet their formulae for doing so are likely to make the difference between enabling pupils with special needs to progress in their learning and, conversely, reducing the support they may need. Tim Lee, research fellow, Centre for the Analysis of Social Policy, Bath University, reports on the latest surveys of LEAs' funding policies. 相似文献
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Seong-Soo Lee 《Instructional Science》1981,10(2):123-133
One hundred and thirty-two 10th graders performed either a conjunetive or biconditional rule task in one of six conditions defined by a 2 (tasks: attribute-identification versus rule-learning) by 3 (memory aids: 0 versus 3 versus 6) factorial design. Learners' attribute-identification was facilitated when six memory aids were made available, especially given the biconditional rule, but not when three aids were available. This effect was attributed to the facilitative role of six memory aids in the process of eliminating irrelevant dimensions. The acquisition of the biconditional rule was a linear function of the number of memory aids; but that of the conjunctive rule was not differentially affected by the memory aids. This interaction was attributed to the facilitative role of memory aids in the formation of a relatively complex one, not in the identification of a familiar, easy one. 相似文献
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Observation of a model prior to physical practice often facilitates the acquisition of motor skills. The majority of research studies on observational motor learning has used a skilled model for the demonstration. Recent research, however, suggests that observing an unskilled (learning) model may also be effective. The experiment reported here compared motor skill acquisition following observation of a learning model or a skilled model to the performance of subjects who lacked the benefit of observation. The task was to play a computer tracking game. Subjects were tested in pairs. Observers watched either a skilled or a learning model perform 3 trials. The observers then practiced the game for 3 trials. Observation of another 12 trials was followed by 12 more practice trials. Substantial observational learning was found, as both groups of observers performed better than the learning models after both the 3 initial trials of observation and after 12 more observation trials. However, there were no differences due to observing the skilled or the learning model. These findings are discussed in relation to theoretical issues of observational learning. 相似文献
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Amit Asthana Kwang Ho Lee Kyeong-Ohn Kim Dong-Myung Kim Dong-Pyo Kim 《Biomicrofluidics》2012,6(1):012821-012821-9
In this paper, we have presented a non-lithographic embedded template method for rapid and cost-effective fabrication of a selectively permeable calcium-alginate (Ca-alginate) based microfluidic device with long serpentine delay channel. To demonstrate the versatility of the presented method, we have demonstrated two different strategies to fabricate serpentine long delay channels without using any sophisticated microfabrication techniques, in formal lab atmosphere. The procedure presented here, also, enables the preparation of a multilayered microfluidic device with channels of varying dimensions, in a single device without using any sophisticated micromachining instrumentation. In addition, we have also qualitatively studied the diffusion of small and large molecules from a Ca-alginate based microfluidic device and proposed a method to effectively control the out-flow of macro biomolecules from the crosslinked Ca-alginate matrix to create a selectively permeable matrix required for various biological and biomimetic applications, as mentioned in the Introduction section of this work. 相似文献
180.
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium resistant to all existing penicillin and lactam-based antimicrobial drugs and, therefore, has become one of the most prevalent antibiotic-resistant pathogens found in hospitals. The multi-drug resistant characteristics of MRSA make it challenging to clinically treat infected patients. Therefore, early diagnosis of MRSA has become a public-health priority worldwide. Conventionally, cell-culture based methodology and microscopic identification are commonly used for MRSA detection. However, they are relatively time-consuming and labor-intensive. Recently, molecular diagnosis based on nucleic acid amplification techniques, such as polymerase chain reaction (PCR), has been widely investigated for the rapid detection of MRSA. However, genomic DNA of both live and dead pathogens can be distinguished by conventional PCR. These results thus could not provide sufficient confirmation of an active infection for clinicians. In this study, live MRSA was rapidly detected by using a new integrated microfluidic system. The microfluidic system has been demonstrated to have 100% specificity to detect live MRSA with S. aureus and other pathogens commonly found in hospitals. The experimental results showed that the limit of detection for live MRSA from biosamples was approximately 102 CFU/μl. In addition, the entire diagnostic protocol, from sample pre-treatment to fluorescence observation, can be automatically completed within 2.5 h. Consequently, this microfluidic system may be a powerful tool for the rapid molecular diagnosis of live MRSA. 相似文献