Haptoglobin Polymorphism and Association with Complications in Ghanaian Type 2 Diabetic Patients

There is scanty information on the role of genetic factors, especially those relating to haptoglobin (Hp) phenotypes in the expression of complications among diabetes mellitus patients in Ghana. In this study, we investigated whether there is any association between Hp phenotypes and diabetic complications and to determine if association of the Hp phenotypes with diabetic complications in Ghanaian diabetics differ from those in Caucasians. A total of 398 participants were randomly recruited into the study. These comprised diabetic patients numbering 290 attending a diabetes Clinic in Ghana and 108 non-diabetic controls from the same community. Analyses of the results indicate that most of the diabetics with complications were of the Hp 2–2 (35%) and Hp 2–1 (23.9%) phenotypes. Fewer diabetics were found to be of the Hp 2–1 M phenotype. The controls were mostly of Hp 1–1 and Hp 2–1 M phenotypes. The odds ratio of having complications in a diabetic with an Hp 2–2 phenotype was 18.27 times greater than that for Hp 0–0. Hp 2–2 phenotype with its poor antioxidant activity may therefore be a useful predictor for the propensity of an individual to develop diabetes complications.     

Pacing during a cross-country mountain bike mass-participation event according to race performance,experience, age and sex

This study describes pacing strategies adopted in an 86-km mass-participation cross-country marathon mountain bike race (the ‘Birkebeinerrittet’). Absolute (km·h^?1) and relative speed (% average race speed) and speed coefficient of variation (%CV) in five race sections (15.1, 31.4, 52.3, 74.4 and 100% of total distance) were calculated for 8182 participants. Data were grouped and analysed according to race performance, age, sex and race experience. The highest average speed was observed in males (21.8?±?3.7?km/h), 16–24?yr olds (23.0?±?4.8?km/h) and those that had previously completed >4 Birkebeinerrittet races (22.5?±?3.4?km/h). Independent of these factors, the fastest performers exhibited faster speeds across all race sections, whilst their relative speed was higher in early and late climbing sections (Cohen's d?=?0.45–1.15) and slower in the final descending race section (d?=?0.64–0.98). Similar trends were observed in the quicker age, sex and race experience groups, who tended to have a higher average speed in earlier race sections and a lower average speed during the final race section compared to slower groups. In all comparisons, faster groups also had a lower %CV for speed than slower groups (fastest %CV?=?24.02%, slowest %CV?=?32.03%), indicating a lower variation in speed across the race. Pacing in a cross-country mountain bike marathon is related to performance, age, sex and race experience. Better performance appears to be associated with higher relative speed during climbing sections, resulting in a more consistent overall race speed.     

Cognitive implications of learning to read

This paper explores possible cognitive consequences of the experience of learning to read. Whilst it is written mostly with young learners in Europe and N. America in mind, much may also bear on the experience of learning later in life and in different cultural contexts. The perspective is intentionally broad, recognizing that literacy has complex social and personal significance and arguing that the conditions of learning combine with the degree of technical mastery to affect thinking powers and conceptions of language, of learning, and of authority. Reference is made to existing literature on learning to read, but much of the argument opens up issues for further exploration rather than demonstrating effects with any certainty.     

THE RELATIONSHIP BETWEEN BIBLE READING AND ATTITUDE TOWARD SUBSTANCE USE AMONG 13-15 YEAR OLDS

The relationship between Bible reading and attitude toward drug use is examined among a sample of 25,888 teenagers, 13-15 year olds, throughout England and Wales. Information about sex, age, personality, belief in God, and church attendance was also considered. The conclusion is that Bible reading makes a small but significant contribution to promoting a negative attitude toward drug use among this age group.     

Teaching French as a Second Language to Chinese students: Instructional staff adaptation and intercultural competence development

This case study is an analysis of second language instructors’ processes of adaptation to Chinese students at a small French University. More precisely, in this qualitative case study, it will be shown that the instructional staff's adaptation to an unfamiliar work environment and student population contributed to the development of their intercultural competence. Moreover, it will be argued that such competence was not developed to its full potential. Finally, we offer recommendations for teacher education programs at the end of the article.