"蚁族"大学毕业生就业现状分析及对策研究

＂蚁族＂大学毕业生是一个不容忽视的新兴弱势群体。应对＂蚁族＂大学毕业生群体的生存现状做出描述,分析＂蚁族＂现象的根源和成因,并以马克思主义为立足点研究对策,给予高度的人文关怀。     

基于Struts+Spring+log4j框架的日志管理

介绍了J2EE的两种开源框架Spring和log4j,以及它们对基于Struts框架的Web应用系统的日志管理功能的实现。以Struts整合Spring的AOP技术以及log4j框架成功地实现了对Web应用系统的日志管理模块,通过上述技术在Web应用程序中的实际应用,说明了利用上述技术可以提高Web应用程序的开发效率,构造出的系统具有良好的可维护性和可扩展性。     

Clodronate-containing liposomes attenuate lung injury in rats with severe acute pancreatitis

Objectives:Severe acute pancreatitis(SAP) can lead to acute lung injury(ALI) .The purpose of this paper is to investigate the protective effect of clodronate-containing liposomes on ALI in rats with SAP.Methods:The thin film method was used to prepare liposomes.Sprague-Dawley rats were randomly divided into three groups.After the SAP model was established by injecting 5%(w/v) sodium taurocholate(2 ml/kg body weight) into the subcapsular space of the pancreata,normal saline was administered to the control(C) group,phosphate buffer solution(PBS) -containing liposome to the Pgroup,and clodronate-containing liposome to the Tgroup through tail veins.Blood samples were obtained from the superior mesenteric vein at 2 and 6 h to measure the levels of amylase,interleukin-6(IL-6) ,and tumor necrosis factor-α(TNF-α) .Morphological changes in the pancreata and lung were observed using hematoxylin and eosin(HE) staining,while cell apoptosis was detected using terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling(TUNEL) .In addition,the macrophage marker cluster of differentiation 68(CD68) in lung tissue was detected with immunohistochemistry.Results:Blood levels of amylase,IL-6,and TNF-αwere significantly increased in the Pgroup compared to those in the Tgroup(P0.05) .In the Tgroup,large numbers of TUNEL-positive cells were observed,but no or few in the C and Pgroups.Gross inspection and HE staining of pancreata and lung showed dramatic tissue damage,including inflammation and necrosis in the Pgroup.Less remarkable changes were noted in the Tgroup,and the C group exhibited normal histology.The histological scores according to Kaiser's criteria were consistent with HE findings.The number of CD68-positive macrophages decreased in the Tgroup.Conclusions:Clodronate-containing liposomes have a protective effect against ALI in rats with SAP.Blockade of macrophages may represent a novel therapeutic strategy in SAP.     

基于名实体的新闻专题自动综述系统研究与实现

自动综述是指针对特定的主题进行多文档自动摘要,最终提供简洁、重要的信息.新闻专题自动综述是多文档自动摘要的一种应用形式,它可以帮助人们快速了解某个新闻事件的概貌.提出了一种基于名实体的新闻专题自动综述方法.该方法首先从新闻专题的文章集合中识别并挑选出代表新闻要素的时间、地点、人物、机构等名实体,经过语义处理后进行名实体的频率统计.然后根据句子中名实体的频率,结合句子位置、长度等因素计算句子的综合权值选出摘要句,最后根据句子的时间戳信息对句子排序输出得到最终的新闻专题综述.实验结果表明,该方法是有效的,具有实用价值.     

我国电子政务软政策的功能及其意义

电子政务软政策在我国电子政务政策体系中占有重要的地位.电子政务软政策的发展具有一定的理论和实践基础,在电子政务发展中发挥着重要的作用,对于我国服务型政府的建设和完善具有一定的意义.     

论知识经济时代图书馆服务比较优势的发挥

随着信息技术的广泛应用,为社会提供文献资料和信息查询服务已不再是图书馆一枝独秀了.图书馆只有顺应形势,努力寻找和开发新的比较优势,才能在激烈的知识经济竞争中站稳脚跟,创造出图书馆服务的勃勃生机.     

Science Letters：IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis with its expression associated with DNA hypomethylation of exon 1

Insulin-like growth factor binding-protein-7 （IGFBP7） was obtained from our previous colonic adenocarcinoma （CRC） and normal mucosa suppression subtraction hybridization （SSH） cDNA libraries. By RT-PCR and immunohistochemistry, we found that IGFBP7 was overexpressed in CRC tissue compared to normal tissue. However, our in vitro experiments performed in 10 CRC cell lines showed that IGFBP7 expressed only in SW480 and Caco2 cell lines, which implied an underlying reversible regulatory mechanism. Using methylation-specific PCR （MSP） and bisulfite sodium PCR （BSP）, we found that its expression was associated with DNA hypomethylation of exonl. This was further supported by the in vitro study which showed restored IGFBP7 expression after demethylation agent 5-aza-2＇-deoxycytidine treatment. Correlation analysis between IGFBP7 expression and prognosis indicated that overexpression of IGFBP7 in CRC tissue correlated with favourable survival. Investigation of the functional role of IGFBP7 through transfection studies showed that IGFBP7 protein could inhibit growth rate, decrease colony formation activity, and induce apoptosis in RKO and SW620 cells, suggesting it a potential tumor suppressor protein in colorectal carcinogenesis. In conclusion, our study clearly demonstrated that IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis and its expression is associated with DNA hypomethylation of exon 1.     

高校博物馆发展现状、问题及对策探讨

高校博物馆是教育系统开展科普活动的重要科普基础设施,如何促进高校博物馆建设对提升我国科技创新能力具有重要意义。本文归纳总结了我国高校博物馆发展现状和问题,分析了制约高校博物馆发展的成因,提出促进高校博物馆发展的若干对策。     

人脸识别在建筑施工远程考勤中的应用

提出通过在智能手机上安装考勤客户端软件,使用GPS技术限定用户位置,利用智能手机强大的计算能力和无线互联网络的高带宽,将人脸识别技术应用在建筑施工远程考勤中的方案.介绍Android平台上OpenCV库所提供的算法接口,分析特征脸、Fisher脸、LBP直方图3种人脸识别算法的选择和应用.方案在实际应用中,取得了较好的效果.