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991.
Lakshmi Lavanya Reddy Swarup A. V. Shah Alpa J. Dherai Chandrashekhar K. Ponde Tester F. Ashavaid 《Indian journal of clinical biochemistry : IJCB》2016,31(1):87-92
Acute coronary syndrome (ACS) is a term for a range of clinical signs and symptoms suggestive of myocardial ischemia. It results in functional and structural changes and ultimately releasing protein from injured cardiomyocytes. These cardiac markers play a major role in diagnosis and prognosis of ACS. This study aims to assess the efficacy of heart type fatty acid binding protein (h-FABP) as a marker for ACS along with the routinely used hs-TropT. In our observational study, plasma h-FABP (cut-off 6.32 ng/ml) and routinely done hs-Trop T (cutoff 0.1 and 0.014 ng/ml) were estimated by immunometric laboratory assays in 88 patients with acute chest pain. Based on the clinical and laboratory test findings the patients were grouped into ACS (n = 41) and non-ACS (n = 47). The diagnostic sensitivity, specificity, NPV, PPV and ROC curve at 95 % CI were determined. Sensitivity of hs-TropT (0.1 ng/ml), hs-TropT (0.014 ng/ml) and h-FABP were 53, 86 and 78 % respectively and specificity for the same were 98, 73 and 70 % respectively. Sensitivity, specificity and NPV calculated for a cut-off combination of hs-TropT 0.014 ng/ml and h-FABP was 100, 51 and 100 % respectively. These results were substantiated by ROC analysis. Measurement of plasma h-FABP and hs-TropT together on admission appears to be more precise predictor of ACS rather than either hs-Trop T or h-FABP. 相似文献
992.
Although the principle of holography was conceived as long ago as 1947, interest was limited until the advent of the laser in 1960 made possible the off-axis holography widely used today. Since then holography has found many applications and become so well known outside the laboratory as to be a recognized art form. Within the last few years considerable progress has also been made in acoustic holography. 相似文献
993.
Ronald E. Rice 《The Information Society》2005,21(4):285-299
This study summarizes prior reviews of new media and Internet research, and the growth of the term Internet in academic publications and online newsgroups. It then uses semantic network analysis to summarize the interests and concepts of an interdisciplinary group of Internet researchers, as represented by session titles and paper titles and abstracts from the 2003 and 2004 Association of Internet Researchers conferences. In both years, the most frequent words appearing in the paper abstracts included Internet, online, community, social, technology, and research. The 2003 papers emphasized topics such as the social analysis/research of online/Internet communication, community, and information, with particular coverage of access, individuals, groups, digital media, culture; role and process in e-organizations; and world development. The 2004 papers emphasized topics such as access; news and social issues; the role of individuals in communities; user-based studies; usage data; and blogs, women, and search policy, among others. 相似文献
994.
Winston Costa Pereira Muddanna S. Rao D. M. Vasudevan 《Indian journal of clinical biochemistry : IJCB》2003,18(2):161-168
Immunization with a proper dose of an antigenic stimulus leads to cell proliferation and antibody response of circulating
lymphocytes. We have previously observed that Secondary immunized spleenocytes resist ceramide-mediated apoptosisin vitro. Our present study is aimed at investigating thein vivo effect of immunization on apoptosis. Mice were subjected to either Primary or Secondary dose with Tetanus Toxoid. Unimmunized
spleenocytes served as controls. Unimmunized, Primary and Secondary immunized mice were later exposed to chemotherapeutic
drugs such as Etoposide/Methotrexate/Vincristine to induce apoptosis. Apoptosis was studied by using the Feulgen reaction
on 5μ thin parafin sections of spleen. It was observed that Secondary immunized mice showed a lower percentage of apoptosis
as compared to Primary or Unimmunized mice that was subjected to either of the chemotherapeutic drugs. It was thus concluded
that Secondary immunization inhibits the process of chemotherapeutic drug induced apoptosis in vivo. 相似文献
995.
996.
We present a new paradigm for the automatic creation of document headlines that is based on direct transformation of relevant textual information into well-formed textual output. Starting from an input document, we automatically create compact representations of weighted finite sets of strings, called WIDL-expressions, which encode the most important topics in the document. A generic natural language generation engine performs the headline generation task, driven by both statistical knowledge encapsulated in WIDL-expressions (representing topic biases induced by the input document) and statistical knowledge encapsulated in language models (representing biases induced by the target language). Our evaluation shows similar performance in quality with a state-of-the-art, extractive approach to headline generation, and significant improvements in quality over previously proposed solutions to abstractive headline generation. 相似文献
997.
Thomas E. Gaston Francesca Ounsworth Tessa Senders Sarah Ritchie Emma Jones 《Learned Publishing》2020,33(2):154-162
Previous research has found that researchers rank journal reputation and impact factor (IF) amongst the key selection criteria when choosing where to submit. We explored the actual effect upon submission numbers of several possible factors. We retrieved 10 years of submission data from over a thousand journals, as well as data on IF, retractions, and other factors. We performed statistical analysis and identified correlations. We also undertook case study research on the 55 most significant submission decreases. We found a statistically significant correlation between changes in IF, ISI percentage ranking, and changes in submissions numbers in subsequent years. We also found a statistically significant effect on submission numbers in the year following the publication of a retraction. Our case studies identified other factors, including negative feedback on the peer review process. Our findings regarding IF confirm previous indications about the significance of IF on submissions. We explain the correlation with retractions through the concept of ‘peer review reputation’. These results indicate that editors and publishers need to focus on a journal's peer review practices, as well as a journal's IF, if they are to maintain and grow submissions. 相似文献
998.
Intelligent use of the many diverse forms of data available on the Internet requires new tools for managing and manipulating
heterogeneous forms of information. This paper uses WHIRL, an extension of relational databases that can manipulate textual
data using statistical similarity measures developed by the information retrieval community. We show that although WHIRL is
designed for more general similarity-based reasoning tasks, it is competitive with mature systems designed explicitly for
inductive classification. In particular, WHIRL is well suited for combining different sources of knowledge in the classification
process. We show on a diverse set of tasks that the use of appropriate sets of unlabeled background knowledge often decreases
error rates, particularly if the number of examples or the size of the strings in the training set is small. This is especially
useful when labeling text is a labor-intensive job and when there is a large amount of information available about a particular
problem on the World Wide Web.
相似文献
Haym HirshEmail: |
999.
Beatrice S. Bartlett 《Archival Science》2007,7(4):369-390
This article describes the first half century of the Communist government’s supervision and management of the central-government
archives of the last two dynasties. Immediately with the Communist ascent to power in 1949, the new government took great
interest in assembling and protecting the country’s archival documents, readying the Ming-Qing archives for access to scholars,
and preparing for publication of selected materials. By the 1980s Beijing’s Number One Historical Archives, in charge of the
largest holding of Ming-Qing documents, had become the first Chinese authority to complete a full sorting and preliminary
catalogues for such a collection. Moreover, to facilitate searches, an attempt has recently begun to create a subject-heading
system for these and other holdings in the country. In the first half century’s final decades, foreign researchers were admitted
for the first time and tours and international exchanges began to take place.
相似文献
Beatrice S. BartlettEmail: |
1000.
Previous papers on grey literature by the authors have described (1) the need for formal metadata to allow machine understanding
and therefore scalable operations; (2) the enhancement of repositories of grey (and other) e-publications by linking with
CRIS (Current Research Information Systems); (3) the use of the research process to collect metadata incrementally reducing
the threshold barrier for end-users and improving quality in an ambient GRIDs environment. This paper takes the development
one step further and proposes “intelligent” grey objects. The hypothesis is in 2 parts: (1) that the use of passive catalogs
of metadata does not scale (a) in a highly distributed environment with millions of nodes and (b) with vastly increased volumes
of R&D output grey publications with associated metadata; (2) that a new paradigm is required that (a) integrates grey with
white literature and other R&D outputs such as software, data, products and patents (b) in a self-managing, self-optimizing
way and that this paradigm manages automatically curation, provenance digital rights, trust, security and privacy. Concerning
(1) existing repositories provide catalogs; harvesting takes increasing time ensuring non-currency. The end-user expends much
manual effort/intelligence to utilize the results. The elapsed time of (1) the network (2) the centralized (or centrally controlled
distributed) catalog server searches (3) end-user intervention becomes unacceptable. Concerning (2) there is no paradigm currently
known to the authors that satisfies the requirement. Our proposal is outlined below. Hyperactive combines both hyperlinking
and active properties of a (grey) object. Hyperlinking implies multimedia components linked to form the object and also external
links to other resources. The term active implies that objects do not lie passively in a repository to be retrieved by end-users.
They “get a life” and the object moves through the network knowing where it is going. A hyperactive grey object is wrapped
by its (incrementally recorded) formal metadata and an associated (software) agent. It moves through process steps such as
initial concept, authoring, reviewing and depositing in a repository. The workflow is based on the rules and information in
the corporate data repository with which the agent interacts. Once the object is deposited, the agent associated with it actively
pushes the object to the end-users (or systems) whose metadata indicate interest or an obligation in a workflowed process.
The agents check the object and user (or system) metadata for rights, privacy, security parameters, and for any charges and
assure compatibility. Alternatively the object can be found passively by end-user or system agents. The object can also associate
itself with other objects forming relationships utilising metadata or content. Declared relationships include references and
citations; workflowed relationships include versions and also links to corporate information and research datasets and software;
inferenced relationships are discovered relationships such as between documents by different authors developed from an earlier
idea of a third author. Components of this paradigm have been implemented to some extent. The challenge is implementing—respecting
part two of the hypothesis—the integration architecture. This surely is harnessing the power of grey.
相似文献
Anne AssersonEmail: |