Programme recruitment and evaluation: the effect of an employability enhancement programme on the general self-efficacy levels of unemployed graduates

This paper reports research that engaged in the evaluation of an intervention programme designed to enhance the employability of a group of unemployed graduates. The evaluation adopted a quasi-experimental intervention research method employing a general self-efficacy scale, which had been validated in prior research. Results revealed that participants displayed higher levels of GSE after engagement in the programme. Results also revealed the effect of ‘behavioural plasticity’ on the intervention experiences of unemployed graduate participants. The findings of this study are discussed in relation to programme design, recruitment and evaluation.     

The how's and why's of biological change: How learners neglect physical mechanisms in their search for meaning

This study describes the trends in students' explanations of biological change in organisms. A total of 96 student volunteers (8 students from each of 2nd, 5th, 8th, and 12th grades from 3 localities) were interviewed individually and each student was presented a series of graphics depicting natural phenomena. Students' explanations to questions of how something occurred were assigned to one of three categories (responses addressing how something occurred, why something occurred, and 'I don't know'). While the number of responses in each category was roughly equivalent in prominence across grade levels, the majority of students were unable to offer a causal explanation of how a phenomena occurred. An unexpected phenomenon was the students' predilection to redirect the interview question so they could answer them. If asked a how question, as they were in every interview instance, 32% the students answered with a 'why' response. The way biology is taught, the structure of biology or/and how we learn it could shed some light into this phenomenon and has implications for science educators.     

Assessment for learning: a catalyst for student self-regulation

The development of students as lifelong, self-regulating learners is a valued outcome of higher education. To this end, the current project investigated how students in an undergraduate course experienced and responded to a teaching–learning environment where they were expected to take responsibility for their learning. The pedagogic environment of this course was grounded in strategies and activities associated with assessment for learning (AfL). As such, students were expected to participate in activities that provided them with opportunities to exercise control over their learning. Data gathering comprised individual semi-structured interviews and the collection of artefacts. Findings indicated goals helped students know where they were going; exemplars provided insights into what was expected and what constituted quality work; course activities elicited evidence of learning; dialogic interactions around these generated feedback about understandings and progress; the evaluation of exemplars developed evaluative knowledge, skill and expertise; peer review and feedback provided an authentic context for evaluation and monitoring of works-in-progress. It was concluded that, while each of the AfL strategies contributed to student self-regulation, the full impact of AfL as a catalyst for self-regulated learning was realised in the cumulative and recursive effect these strategies had on students’ thinking, actions and feelings.     

Learning to read

Summary Reading begins with the child’s acquisition of spoken language. Later he learns to differentiate the graphic symbols from one another and to decode these to familiar speech sounds. As he learns the code, he must progressively utilize the structural constraints which are built into it in order to attain the skilled performance which is characterized by processing of higher-order units—the spelling and morphological patterns of the language. Because of my firm conviction that good pedagogy is based on a deep understanding of the discipline to be taught and the nature of the learning process involved, I have tried to show that the psychology of reading can benefit from a program of theoretical analysis and experiment. An analysis of the reading task—its discriminatory and decoding aspects as well as the semantic and syntactical aspects—tells uswhat must be learned. An analysis of the learning process tells ushow. The consideration of formal instruction comes only after these steps, and its precepts should follow from them. This article is adapted from a paper used at a conference on Perceptual and Linguistic Aspects of Reading, sponsored by the Committee on Learning and the Educational Process of the Social Science Research Council and held at the Center for Advanced Study in the Behavioral Sciences, Palo Alto, California, 31, October 1963. Reprinted by permission of the Author and Publisher from Science, V. 148, No. 3673, 21 May 1965.     

CRISPR/Cas: a Nobel Prize award-winning precise genome editing technology for gene therapy and crop improvement

Since it was first recognized in bacteria and archaea as a mechanism for innate viral immunity in the early 2010 s,clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein(Cas) has rapidly been developed into a robust, multifunctional genome editing tool with many uses. Following the discovery of the initial CRISPR/Cas-based system, the technology has been advanced to facilitate a multitude of different functions. These include development as a base editor, prime editor, epigenetic editor, and CRISPR interference(CRISPRi) and CRISPR activator(CRISPRa) gene regulators. It can also be used for chromatin and RNA targeting and imaging. Its applications have proved revolutionary across numerous biological fields, especially in biomedical and agricultural improvement. As a diagnostic tool, CRISPR has been developed to aid the detection and screening of both human and plant diseases, and has even been applied during the current coronavirus disease 2019(COVID-19) pandemic. CRISPR/Cas is also being trialed as a new form of gene therapy for treating various human diseases, including cancers, and has aided drug development. In terms of agricultural breeding, precise targeting of biological pathways via CRISPR/Cas has been key to regulating molecular biosynthesis and allowing modification of proteins, starch, oil, and other functional components for crop improvement. Adding to this, CRISPR/Cas has been shown capable of significantly enhancing both plant tolerance to environmental stresses and overall crop yield via the targeting of various agronomically important gene regulators. Looking to the future, increasing the efficiency and precision of CRISPR/Cas delivery systems and limiting off-target activity are two major challenges for wider application of the technology. This review provides an in-depth overview of current CRISPR development, including the advantages and disadvantages of the technology,recent applications, and future considerations.