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451.
This paper reports the development of a scalable continuous microfluidic-based method for the preparation of multilayered biopolymer microcapsules and microparticles, with a size range of 1 to 100 μm, in a single-layered polydimethylsiloxane-based device. This new approach has been utilised to produce polyethylene oxide (PEO)-based microparticles, layered with subsequent stage wise coatings of polylactide-based block copolymers and polyvinylpyrrolidone. The production process was shown to allow for on-chip encapsulation of protein and vitamin molecules in the biopolymer micro particles, without any further handling after collection from the device. We have studied the release profiles in the case of model molecules of distinctive molecular weights, namely, vitronectin, horse radish peroxidase, and vitamin B(12). We compared the release properties of the microparticles to those from macro-gels of the same materials prepared off-chip. The results indicated that the microparticles have definitively different molecular weight cut-off characteristics, likely due to a denser microstructure within the microparticles compared to the bulk hydrogels. This difference suggests that significant benefits may exist in the use of this method to produce layered biopolymer microparticles in achieving improved controlled release and encapsulation. 相似文献
452.
A test of advanced theory of mind (ToM), first introduced by F. Happé (1994) , was adapted for children (mental, human, animal, and nature stories plus unlinked sentences). These materials were closely matched for difficulty and were presented to forty-five 7- to 12-year-olds with autism and 27 control children. Children with autism who showed ToM impairment on independent tests performed significantly more poorly than controls solely on the mental, human, and animal stories with greatest impairment on the former and least on the latter. Thus, a mentalizing deficit may affect understanding of biologic agents even when this does not explicitly require understanding others' mental states. 相似文献
453.
我在美国宾夕法尼亚州的邓莫尔长大,我曾经是第66童子军小队的成员:我们开展过很多有趣的活动。其中一项就是松木结构的赛车设计比赛,即模型汽车比赛。 相似文献
454.
In recent years, technology has made it possible, and in some ways critical, for college and university presidents to increase campus‐wide communication. Following the 2016 US presidential election, many college presidents across the country sent campus‐wide communications in response to the election, while others chose not to respond. The resulting reactions from campus and community stakeholders to these communications, or the lack of communication, from presidents was mixed due to the contentious nature of the election. In an effort to better understand a president’s decision to communicate, this study utilised coded interviews with 12 US flagship institution presidents or vice‐presidents for communication, providing insight into why presidents generally respond to contentious events and, more specifically, why presidents chose to respond to the 2016 election of Donald Trump. Four motivations that generally influenced presidential communications were identified (i.e., responsibility to campus stakeholders, pressure to respond, emphasise university values and the role of a public university), and subsequent sub‐themes were identified while analysing why presidents responded to the 2016 election specifically. This study concludes by offering implications for presidential communication and directions for future research on presidential engagement with contentious events. 相似文献
455.
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457.
Elisabeth H. Wiig 《Annals of dyslexia》1991,41(1):1-22
We are beginning a decade, during which many traditional paradigms in education, special education, and speech-language pathology
will undergo change. Among paradigms considered promising for speech-language pathology in the schools are collaborative language
intervention and strategy training for language and communication. This presentation introduces management models for developing
a collaborative language intervention process, among them the Deming Management Method for Total Quality (TQ) (Deming 1986).
Implementation models for language assessment and IEP planning and multicultural issues are also introduced (Damico and Nye
1990; Secord and Wiig in press). While attention to processes involved in developing and implementing collaborative language
intervention is paramount, content should not be neglected. To this end, strategy training for language and communication
is introduced as a viable paradigm. Macro- and micro-level process models for strategy training are featured and general issues
are discussed (Ellis, Deshler, and Schumaker 1989; Swanson 1989; Wiig 1989).
The Samuel Torrey and June Lyday Orton Memorial Lecture, delivered at the 41st Annual Conference of The Orton Dyslexia Society,
Washington, DC., November 1, 1990. 相似文献
458.
ABSTRACTAlthough more nuanced understandings of assessment have been proposed in the physical education literature, assessment practices remain relatively underdeveloped, and when used, tend to focus on traditional, summative evaluations of learning. However, physical education teacher education programs can be used as an intervention to help pre-service teachers develop assessment knowledge and skill. Toward this end, the purpose of this article is to propose an evidence-based framework for helping pre-service teachers develop assessment literacy that is rooted in occupational socialization theory. The framework provides a four-phase approach to integrating assessment into teacher education, and includes suggestions for how physical education teacher educators can progressively help build pre-service teachers’ assessment knowledge in line with the focus given to instruction and planning. These suggestions acknowledge the technical and sociocultural aspects of learning to use assessment. Implications are discussed along with the need to help graduating pre-service teachers transfer lessons learned into the workplace. 相似文献
459.
Kendall Richards Nick Pilcher 《International journal of qualitative studies in education》2013,26(5):604-625
Key ‘generic’ assessment task words such as ‘discuss’ and ‘critically evaluate’ are integral to higher education assessment. Although sources such as study skills guides give generic decontextualised glossaries of these words, much research rightly argues for greater dialogue between students (particularly ‘non-traditional’ students) and lecturers to help students understand and use such words. This paper presents the results from ‘staged’ focus groups with lecturers and students from the UK and China that created a forum for such dialogue, where many of these words and their interpretations were talked about. Results show very different interpretations, informed by factors such as ‘language’, ‘culture’ and ‘subject’. We propose these factors be used in an ‘anti-glossary’ approach, which we describe here. This approach is not against glossaries per se, but counteracts the assumption that glossary definitions are explicit, and adopts a social constructivist contextualisation of the task words through teacher-led dialogue. 相似文献
460.
Elisabeth Raes Stefan Decuyper Bart Lismont Piet Van den Bossche Eva Kyndt Sybille Demeyere Filip Dochy 《Instructional Science》2013,41(2):287-305
This article investigates when and how teams engage in team learning behaviours (TLB). More specifically, it looks into how different leadership styles facilitate TLB by influencing the social conditions that proceed them. 498 healthcare workers from 28 nursery teams filled out a questionnaire measuring the concepts leadership style, TLB, social cohesion and team psychological safety. Analysis was performed using structural equation modelling. The results of this cross-sectional study show that transformational leadership predicts TLB better then laissez-faire leadership, because transformational leadership is primarily related to team psychological safety and only secondarily to social cohesion while for laissez-faire leadership it works the other way around. Transformational leadership matters because it facilitates psychological safety in the team. 相似文献