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Miller PR Gittard SD Edwards TL Lopez DM Xiao X Wheeler DR Monteiro-Riviere NA Brozik SM Polsky R Narayan RJ 《Biomicrofluidics》2011,5(1):13415
In this study, carbon fiber electrodes were incorporated within a hollow microneedle array, which was fabricated using a digital micromirror device-based stereolithography instrument. Cell proliferation on the acrylate-based polymer used in microneedle fabrication was examined with human dermal fibroblasts and neonatal human epidermal keratinocytes. Studies involving full-thickness cadaveric porcine skin and trypan blue dye demonstrated that the hollow microneedles remained intact after puncturing the outermost layer of cadaveric porcine skin. The carbon fibers underwent chemical modification in order to enable detection of hydrogen peroxide and ascorbic acid; electrochemical measurements were demonstrated using integrated electrode-hollow microneedle devices. 相似文献
55.
56.
Australia, like the rest of the developed world, is in the midst of dealing with notable issues related to the age structure
of its academic workforce. These issues are widespread and have been articulated in the Australian context most comprehensively
by Hugo (2008). This paper investigates issues with demographic change and other key factors related to the desirability of a science or
mathematics academic career within Australian universities. It draws on the findings of a research project undertaken in 2008
for the Department of Education, Employment and Workplace Relations. The findings show that while demographic issues are not
as dire for science academics compared to the entire sector, issues relating to tenure, workload and retaining young science
academics in Australia are a threat to the long-term sustainability of science faculties in Australian universities. 相似文献
57.
Research Findings: The objective of this study was to understand how two dimensions of parent–child book-reading quality—instructional and emotional—interact and relate to learning in a sample of low-income infants and toddlers. Participants included 81 parents and their children from Early Head Start programs in the rural Midwest. Correlation and multiple regression analyses were used to test the hypothesis that parental book-reading qualities interact and relate to children's concurrent cognitive and language scores. Exploratory analyses examined if patterns of relationships varied for families who had different home languages (i.e., English, Spanish). Results included that book-reading qualities and home language interacted to predict child scores. Practice or Policy: Findings suggest a need to further explore potentially complex patterns of relationships among parental book-reading behaviors and child learning for diverse families. Understanding these patterns could inform the development of culturally-sensitive intervention approaches designed to support high-quality shared book reading. 相似文献
58.
Xiaorong Huang Manfred Kerber Michael Kohlhase Erica Melis Dan Nesmith J?rn Richts und J?rg Siekmann 《Informatik - Forschung und Entwicklung》1996,11(1):20-26
Zusammenfassung.
Die Beweisentwicklungsumgebung -Mkrpsoll
Mathematiker bei einer ihrer
Hauptt?tigkeiten, n?mlich dem Beweisen mathematischer Theoreme
unterstützen. Diese Unterstützung mu? so komfortabel sein,
da? die
rechnergestützte Suche nach formalen Beweisen leichter und insbesondere
weniger aufwendig ist, als ohne das System. Dazu mu? die verwendete
Objektsprache ausdrucksstark sein, man mu? die M?glichkeit haben, abstrakt
über Beweispl?ne zu reden, die gefundenen Beweise müssen in einer am
Menschen orientierte Form pr?sentiert werden und vor allem mu? eine
effiziente Unterstützung beim Füllen von Beweislücken zur Verfügung
stehen. Das im folgenden vorgestellte $\Omega$-Mkrp-System ist
der Versuch einer
Synthese der Ans?tze des vollautomatischen, des interaktiven und des
planbasierten Beweisens. Dieser Artikel soll eine übersicht über unsere
Arbeit an diesem System geben.
Eingegangen am 24. Juni 1994 / Angenommen am 3. November 1995 相似文献
59.
Lana Edwards Santoro Michael D. Coyne Deborah C. Simmons 《Learning disabilities research & practice》2006,21(2):122-133
Abstract In this article, we describe the development and evaluation of a beginning spelling intervention for young children at risk of reading disability. We first summarize the literature that supports beginning spelling as an ideal method for strategically integrating the beginning reading big ideas of phonemic awareness and alphabetic understanding. We then summarize the literature on effective instructional principles for students at risk of reading disability. Next, we describe how instructional design was applied to the development of an intervention for young children at risk of reading disability, then summarize the findings of an experimental study supporting the effectiveness of this intervention. Finally, we provide selected examples from the spelling intervention to illustrate the findings' translation into instructional practice. 相似文献
60.
Ken Edwards 《Higher Education in Europe》2006,31(3):289-293
This paper describes briefly the academic tenure and its legislative terms in the UK, over the last twenty years. The author refers to the current wider situation/trends in the international higher education arena of two categories of academic staff – “established” staff (on permanent contract) and fixed‐term staff – and to how their levels of protection can have an impact on the overall health of the universities and their academic freedom. 相似文献