Effect of vitamin C and E activity on surgically removed cataractous human lens epithelium cells

Oxidative stress has been proposed as a common underlying mechanism of cataractogenesis. Experimental and observational data suggest that micronutrients like vitamin C and vitamin E with antioxidant capabilities may retard the development of age-related cataract. Effect of these factors on lens epithelium cells, center of lens metabolic activities, is not completely elucidated. The aim of present study was to examine the effect of vitamin C and E on surgically removed lens epithelium cells of patients with cataract. Capsulorhexis samples were collected from 170 patients, admitted for cataract surgery. Catalase specific activity was estimated in lens epithelium cells with and without vitamin (C or E) treatment at different concentration for different time duration. Student’s t-test was employed for data analysis. We observed that in ex-vivo condition, a) both vitamin C and E bring about a decrease in catalase activity in lens epithelial cells. b) vitamin C showed toxic effect at high concentration. c) 100μM was the optimum concentration at which both vitamins showed maximum antioxidant activity. It was concluded that both vitamin C and E has direct effect on lens epithelium cells. At optimum concentration, they can reduce oxidative stress in these cells thus can support to prevent or delay cataract development.     

Kinematic analysis of the shot-put: A method of assessing the mechanical work of the hand action force

The aims of this study were to (1) propose a method for evaluating shot-putters mechanical power, (2) investigate the relationship between mechanical work of hand action force (W_HAF), peak power output (PPO) of different limbs and shot-put performance and (3) show which of these two parameters (W_HAF, PPO) were the most appropriate to characterize the explosive abilities of the shot-putter. Twelve junior right-handed shot-putters, practised glide technique shot-put throwers (personal best?=?13.57 ± 1.72 m), participated in this study. Arm and leg force-velocity tests were performed to measure PPO. Kinematic analysis was conducted during a shot-putting event in regular conditions to quantify the W_HAF at the release moment and shot-put performance. Significant correlations were found between absolute arm and leg PPO with upper and lower muscle volumes (r?=?.67; p?=?.03; r?=?.76; p?=?.01; r?=?.74, p?=?.01; r?=?.65, p?=?.04). Positive relationships were recorded between absolute arm and leg PPO and shot-put performance (r?=?.67, p?=?.02; r?=?.81, p?=?.004, respectively). Shot-put performance was also closely related to the W_HAF (r?=?.93, p?=?.0001) and release velocity parameter (r?=?.86, p?=?.001). The present results confirm that force-velocity test and W_HAF constitute useful tools for assessing mechanical power in throwing. The W_HAF could be considered as more suitable than force-velocity test.     

Electroplating for high aspect ratio vias in PCB manufacturing： enhancement capabilities of acoustic streaming

This paper considers the copper electrodeposit ion processes in microvias and investigates whether the quality of the electroplating process can be improved by acoustic streaming using megasonic transducers placed into a plating cell. The theoretical results show that acoustic streaming does not take place within the micro-via （either through or blind-via＇ s）, however it does help improve cupric ion transport in the area close to the mouth of a via. This replenishment of cupric ions at the mouth of micro-via leads to better quality filling of the micro-via through diffusion compared to basic conditions. Experiments showing the improved quality of the filling of vias are also presented.     

Serum Levels of Glycoproteins are Elevated in Patients with Ovarian Cancer

Identification of reliable biomarkers for detection and staging of cancer and monitoring the outcome of anticancer therapy has been considered to be of high importance. We aimed to estimate the levels of serum glycoproteins, protein bound-hexose, protein bound hexosamine, protein bound fucose, protein bound sialic acid and protein bound carbohydrate in 32 ovarian cancer patients and compared them with the levels that found in 25 normal subjects. As compared to the normal subjects, all the four fractions of glycoproteins level were significantly elevated in ovarian cancer patients (p < 0.05). Chemotherapy in these patients significantly decreased the levels of serum glycoproteins (p < 0.05). Thus, high levels of serum glycoproteins in ovarian cancer patients could be due to abnormal protein glycosylation indicating malignant transformation of the cells.     

Monitoring and Root Cause Analysis of Clinical Biochemistry Turn Around Time at an Academic Hospital

Quality can be defined as the ability of a product or service to satisfy the needs and expectations of the customer. Laboratories are more focusing on technical and analytical quality for reliability and accuracy of test results. Patients and clinicians however are interested in rapid, reliable and efficient service from laboratory. Turn around time (TAT), the timeliness with which laboratory personnel deliver test results, is one of the most noticeable signs of laboratory service and is often used as a key performance indicator of laboratory performance. This study is aims to provide clue for laboratory TAT monitoring and root cause analysis. In a 2 year period a total of 75,499 specimens of outdoor patient department were monitor, of this a total of 4,142 specimens exceeded TAT. With consistent efforts to monitor, root cause analysis and corrective measures, we are able to decreased the specimens exceeding TAT from 7–8 to 3.7 %. Though it is difficult task to monitor TAT with the help of laboratory information system, real time documentation and authentic data retrievable, along with identification of causes for delays and its remedial measures, improve laboratory TAT and thus patient satisfaction.     

The relationship between bowling action classification and three-dimensional lower trunk motion in fast bowlers in cricket

Abstract

Lower back injuries, specifically lumbar stress fractures, account for the most lost playing time in professional cricket. The aims of this study were to quantify the proportion of lower trunk motion used during the delivery stride of fast bowling and to examine the relationship between the current fast bowling action classification system and potentially injurious kinematics of the lower trunk. Three-dimensional kinematic data were collected from 50 male professional fast bowlers during a standing active range of motion trial and three fast bowling trials. A high percentage of the fast bowlers used a mixed bowling action attributable to having shoulder counter-rotation greater than 30°. The greatest proportion of lower trunk extension (26%), contralateral side-flexion (129%), and ipsilateral rotation (79%) was used during the front foot contact phase of the fast bowling delivery stride. There was no significant difference in the proportions of available lower trunk extension, contralateral side-flexion, and ipsilateral rotation range of motion used during fast bowling by mixed and non-mixed action bowlers. Motion of the lower trunk, particularly side-flexion, during front foot contact, in addition to variables previously known to be related to back injury (e.g. shoulder counter-rotation), should be examined in future cross-sectional and prospective studies examining the fast bowling action and low back injury.     

Balancing Head and Heart: The Importance of Relational Accountability in Community-University Partnerships

In this article we introduce a “head and heart” approach to community-engaged scholarship. Through the literatures of Aboriginal scholarship and engaged scholarship we reflect on a community-university research and program development project undertaken in response to health and education concerns of Aboriginal people in Canada. We suggest that the head and heart approach was crucial to the program’s success and provides access to an ethical space where multiple worldviews are recognized and where the importance of relational accountability becomes evident. We then examine the implications of this approach for engaged scholarship and higher education practices.     

The home front: citizens behind the camera

In the context of intense debate over immigration into the United States, the television show Border Wars offers a distinctive way for anxious citizens to participate in reinforcing the border. In the program, viewers are invited to share the lines of site of Customs and Border Patrol (CBP) agents as they conduct surveillance of unauthorized border crossers. Because Latino bodies are repeatedly displayed as the subjects of surveillance, the positions of viewer/citizen and viewed-non-citizen encourage racial alignments with the border. In the face of these alignments, the Latino CBP agents are made readable as bodies in transition toward citizenship due to their performance of surveillance practices against other Latinos. The article comments on the soldier citizen as positioned at the panoptic center of watching without being watched, which is less available to Latinos because their bodies circulate as signs of suspicion, which casts them disproportionately onto the surveillance screen. Practices of surveillance should be understood as performances because they reaffirm Americans of their citizenship status at a time of heightened paranoia over the loss of a stable identity.