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941.
942.
C. S. Parameswari B. Vijayageetha R. Vijayakumar 《Indian journal of clinical biochemistry : IJCB》2006,21(1):131-136
The oxidative modification of lipoprotein especially low density lipoprotein (LDL) plays a key role in the initiation and
progression of atherosclerosis. Serum apolipoproteinB (apoB) level is found to be an important marker for atherosclerosis.
The present paper focuses on the measurement of serum apoB levels and the effect of Vitamin E, Vitamin C and reduced glutathione
on the copper ion induced oxidation of LDL + VLDL (VLDL-Very Low Density Lipoprotein) lipoprotein fraction isolated from the
serum of chronic renal failure (CRF) and renal transplanted patients. The level of apoB is significantly higher in the serum
of transplanted patients when compared to CRF patients and normal subjects. The level of TBARS formed in oxidized LDL + VLDL
lipoprotein fraction of CRF and renal transplanted patients are significantly increased than normal even in the presence of
antioxidants but the level of TBARS produced, with antioxidants is comparatively lesser than that produced by oxidized lipoprotein
fraction without antioxidants. It may be concluded than that produced by oxidized lipoprotein fraction without antioxidants.
It may be concluded that oxidation of LDL can be prevented at an earlier stage by Vitamin E supplementation. The supplementation
with Glutathione serves as the best method of preventing the lipoprotein oxidation among the renal diseased patients. 相似文献
943.
My avatar,my self: Virtual harm and attachment 总被引:1,自引:0,他引:1
Jessica Wolfendale 《Ethics and Information Technology》2007,9(2):111-119
Multi-user online environments involve millions of participants world-wide. In these online communities participants can use
their online personas – avatars – to chat, fight, make friends, have sex, kill monsters and even get married. Unfortunately
participants can also use their avatars to stalk, kill, sexually assault, steal from and torture each other. Despite attempts
to minimise the likelihood of interpersonal virtual harm, programmers cannot remove all possibility of online deviant behaviour.
Participants are often greatly distressed when their avatars are harmed by other participants’ malicious actions, yet there
is a tendency in the literature on this topic to dismiss such distress as evidence of too great an involvement in and identification
with the online character. In this paper I argue that this dismissal of virtual harm is based on a set of false assumptions
about the nature of avatar attachment and its relation to genuine moral harm. I argue that we cannot dismiss avatar attachment
as morally insignificant without being forced to also dismiss other, more acceptable, forms of attachment such as attachment
to possessions, people and cultural objects and communities. Arguments against according moral significance to virtual harm
fail because they do not reflect participants’ and programmers’ experiences and expectations of virtual communities and they
have the unintended consequence of failing to grant significance to attachments that we take for granted, morally speaking.
Avatar attachment is expressive of identity and self-conception and should therefore be accorded the moral significance we
give to real-life attachments that play a similar role.
A shorter version of this paper was presented at the Cyberspace 2005 Conference at Masaryk University, Brno, Czech Republic 相似文献
944.
945.
A method for model order reduction is proposed using response-matching technique. The step and impulse inputs have been considered. All types of pole configurations in the original high-order and reduced low-order system are included in this paper like real, complex and repeated. The proposed method is comparable in quality with similar existing methods and is capable of generating a reduced-order model with a desired pole pattern. 相似文献
946.
S. Suchalatha C. S. Shyamala Devi 《Indian journal of clinical biochemistry : IJCB》2004,19(2):184-189
To study the protective role of Arogh on isoproterenol induced myocardial damage in rats. The effect of Arogh pretreatment
on isoproterenol induced myocardial damage was assessed by studying the levels of lipid peroxides and changes in the activity
of marker enzymes such as creatine kinase, lactate dehydrogenase and transaminases in serum and heart tissue. In isoproterenol
administered rats, a significant decrease was observed in the activity of marker enzymes in the heart with a corresponding
increase in their levels in serum. Lipid peroxide levels increased significantly in the serum and heart. In rats pretreated
with arogh, the level of lipid peroxides and the activity of marker enzymes were maintained at near normal values. Pretreatment
with Arogh offered a protective effect against isoproterenol induced myocardial damage in rats as evidenced by LDH isoenzyme
patterm and histopathological studies of heart tissue. 相似文献
947.
948.
Ajay Kumar D. H. Shah M. G. R. Rajan U. R. Thakare S. M. Sharma 《Indian journal of clinical biochemistry : IJCB》1992,7(2):159-164
An external quality assessment was conducted to assess the performance of various laboratories for RIA of thhyroid related
hormones in two phases. In the first phase thirty five laboratories participated. At the end of first phase a meeting cum
workshop was organised to discuss the results of first phase, difficultires faced by the participants and pinpoint the short
oming. A second phase was then initiated with an objective of improvement in the performance, if any, where twelve samples
from four pools were distributed to twenty four laboratories who participated for the second phase. The overall return of
the results increased significantly from 71.8% (1586/2208) for the first phase to 92.4% (732/792) for the second phase. The
inter laboratory %CV for T3, T4 and TSH were lower during the second phase (30.6%, 19.0% and 31.6% respectively) as compared to those observed during first
phase (36.3%, 22.7% and 52.8% respectively). Similarly, there was an improvement in reproducibility of ALTM as %CV for T3, T4 and TSH decreased from 6.0%, 9.8% and 13.4% respectively to 4.5%, 4.6% and 8.5% respectively. The individual performances
of the participating laboratories viz. bias, variability of bias and imprecision also showed a trend towards improvement as
percent laboratories having desirable or acceptable results for T3, T4 and TSH increased from 10.7%, 60.7% and 0.0% respectively to 20.8%, 66.7% and 22.2% respectively. External quality assessment
thus appears to be beneficial in assessing the performane of a laboratory in comfparison with other laboratories and indeed
helps in improving the performance. 相似文献
949.
S. K. Bansal H. N. Pandey A. Bansal L. D. Joshi 《Indian journal of clinical biochemistry : IJCB》1992,7(2):179-184
Circadian rhythm of serum glucose, pyruvate, lactate and lactate dehydrogenase (LDH) was studied in normal healthy young volunteers
at the onset (I Group, 7 cases) and peak (II Group, 8 cases) of winters in India with highly varied temperature. There was
a significant difference, in the circadian rhythm of glucose, pyruvate and lactate dehydrogenase (LDH) of the two groups.
A clockwise shift was observed in acrophase except in serum lactate, which is related to the energy demand in association
with time qualified changes in diurnal activity of the individuals and change in photoperiod. 相似文献
950.
Seema Gupta Rajesh Pandey Ranjan Katyal H. K. Aggarwal R. P. Aggarwal S. K. Aggarwal 《Indian journal of clinical biochemistry : IJCB》2005,20(1):67-71
The present study was conducted to evaluate some of the components of antioxidant defense system and oxidative damage in 20
male patients of alcoholic liver disease (ALD). The results were compared with 20 healthy male smokers and 20 healthy male
non-smokers volunteers. Patients were subjected to detailed clinical examination and laboratory investigations. Blood samples
were collected for estimating reduced glutathione (GSH), total thiols (T-SH) malondialdehyde (MDA), transaminases (AST, ALT),
glutathione-S-transferease (GST) and gammaglutamyl transferase (GGT). Serum aspartate amino transferase (AST)/alanine amino
transferase (ALT) ratio was significantly (p<0.01) reduced in ALD patients as compared to the controls. However, the core
of utility of MDA and GST was found to be significantly (p<0.01) increased in ALD patients compared to controls. There was
a significant negative correlation of MDA with both GSH and TSH. Plasma GGT levels were significantly (p<0.01) increased in
alcoholics and the enzyme showed a significant positive correlation with MDA. These results give enough evidence of increased
oxidative stress and compromised antioxidant defense system in patients with ALD. 相似文献