Physical activity and lipidomics in a population at high risk of type 2 diabetes mellitus

ABSTRACT

The aim was to investigate how measurements of the lipidome differ according to the level and intensity of physical activity in a population at high risk of type 2 diabetes (T2DM). A targeted metabolomics platform provided quantitative molecular data on lipid species. Linear regression examined the associations between plasma lipid concentrations, particle size and time spent in objectively measured physical activity intensity domains, in increments of 500 counts per minute (cpm) (up to >4500 cpm (~>5.6METs)). Results are presented as % difference in the concentration (lower/higher) or particle size (smaller/larger) per 10 min of activity within each intensity. Five hundred and nine participants were included. Time spent in the lowest physical activity intensity domain (<500 cpm) was unfavourably associated with VLDL (2%), HDL (?2%) and Apolipoprotein A-1 particle concentrations (?2%) and HDL diameter (?2%). Conversely, time spent in intensities ≥1000 cpm were favourably associated with HDL subclass concentrations; with stronger associations seen at moderate intensities (2000-3999 cpm (~4.5METs)). For Apolipoprotein-B concentration and VLDL particle concentration and size, a negative association was consistently observed at the highest physical activity intensity only. If these associations are causal, HDL subclasses appear sensitive to light-intensities whereas only the high category of physical activity intensity was consistently associated with VLDL subclasses.     

Validity of a Tympanic Thermometer and Thermal Imaging Camera for Measuring Core and Skin Temperature during Exercise in the Heat

ABSTRACT

This study compared criterion to minimally invasive, practical measures of core (T_c) and skin (T_sk) temperature during 30 min of moderate-intensity cycle exercise in a heat chamber (35°C, 60% rH). T_c was monitored using a core temperature pill (T_c(Pill)) and tympanic thermometer (T_c(Tymp)) during rest, exercise, and recovery in 15 participants. T_sk was monitored using hard-wired skin thermistors attached to a data logger (T_sk(T)) and a thermal imaging camera (T_sk(IR)) in 11 participants. T_c measurement resulted in no significant difference (p > 0.05), a mean bias of 0.1°C, coefficient of variation (CV%) of 1.0%, and correlation of r = 0.74 between devices. T_sk measurement resulted in a significant difference (p = 0.01), a mean bias of 0.6°C, CV% of 2.3%, and correlation of r = 0.61 between devices. T_c(Tymp) demonstrated acceptable agreement with T_c(Pill); however, caution is advised when using T_sk(IR) to give accurate measures of T_sk during exercise.     

Re-conceptualising the paradox in policy implementation: a post-modernist conceptual approach

A review of education policy and practice indicates a paradox in policy implementation. Policy outcomes most often differ significantly from intended purposes and provisions enacted. This paper re-conceptualises this policy phenomenon, drawing on the post-modernist conception of policy as both ‘text’ and ‘discourse’ as an approach for understanding and unmasking the messiness and contested nature of education policy processes. The choice of approach is based on three factors. First, the choice is grounded in its efficacy in explicating and legitimatising the issues of power within the policy arena. Second, the choice is based on the potential of the approach in integrating social and political theories of discourse with more linguistically oriented approaches to the study of policy. Third, the preference of approach follows from its potential to draw on language as a resource for reading into and/or analysing complex social issues.     

Children's Early Awareness of Comprehension as Evident in Their Spontaneous Corrections of Speech Errors

A crucial human cognitive goal is to understand and to be understood. But understanding often takes active management. Two studies investigated early developmental processes of understanding management by focusing on young children's comprehension monitoring. We ask: When and how do young children actively monitor their comprehension of social-communicative interchanges and so seek to clarify and correct their own potential miscomprehension? Study 1 examined the parent–child conversations of 13 children studied longitudinally in everyday situations from the time the children were approximately 2 years through 3 years. Study 2 used a seminaturalistic situation in the laboratory to address these questions with more precision and control with 36 children aged 2–3 years.     

How should researchers in Education operationalise on-task behaviours?

On-task and off-task behaviours have been used in educational research either as independent topics of interest or as dependent variables. In clinical research, there is general agreement about what constitutes off-task behaviours but no such agreement exists for on-task behaviours. This paper reviews 54 studies spanning the last 22?years in order to examine how on-task behaviour has been defined in the educational literature. From the 54 studies, 25 different on-task behaviours were identified. The 25 on-task behaviours were assessed to see if they could be allocated to a category. Four categories of behaviours were identified: task-related, teacher-related, social and miscellaneous. Building on the analysis from the identification and categorisation of the behaviours, the paper suggests a checklist of behaviours that differ in degree of how necessary they are to include in research when using on-task behaviours as a dependent measure. The paper concludes by suggesting that, although on-task behaviours can be highly and appropriately idiosyncratic, educational researchers can achieve some systematicity of measurement by using the guidelines presented.     

Learning to play the seminar game: students’ initial encounters with a basic working form in higher education1

This paper demonstrates how the introduction of the word scholarship in respect to teaching has become confused and misplaced and used to sustain and enhance a particular type of credibility to activities related to the enhancement of learning and teaching in higher education. Bourdieu's concept of symbolic culture is used to construct the argument and show how the use of the term ‘Scholarship of Teaching’ needs to be re‐examined and conceptualized. Twenty‐five academics from a variety of disciplines were interviewed to give their perceptions on the notion of scholarship, the scholarship of teaching, and the scholarship in teaching. These data were used to develop a framework for understanding and possibly reconsidering the role of the scholarship of teaching.