Combining fiber dissection,plastination, and tractography for neuroanatomical education: Revealing the cerebellar nuclei and their white matter connections

In recent years, there has been a growing interest in white matter anatomy of the human brain. With advances in brain imaging techniques, the significance of white matter integrity for brain function has been demonstrated in various neurological and psychiatric disorders. As the demand for interpretation of clinical and imaging data on white matter increases, the needs for white matter anatomy education are changing. Because cross‐sectional images and formalin‐fixed brain specimens are often insufficient in visualizing the complexity of three‐dimensional (3D) white matter anatomy, obtaining a comprehensible conception of fiber tract morphology can be difficult. Fiber dissection is a technique that allows isolation of whole fiber pathways, revealing 3D structural and functional relationships of white matter in the human brain. In this study, we describe the use of fiber dissection in combination with plastination to obtain durable and easy to use 3D white matter specimens that do not require special care or conditions. The specimens can be used as a tool in teaching white matter anatomy and structural connectivity. We included four human brains and show a series of white matter specimens of both cerebrum and cerebellum focusing on the cerebellar nuclei and associated white matter tracts, as these are especially difficult to visualize in two‐dimensional specimens and demonstrate preservation of detailed human anatomy. Finally, we describe how the integration of white matter specimens with radiological information of new brain imaging techniques such as diffusion tensor imaging tractography can be used in teaching modern neuroanatomy with emphasis on structural connectivity. Anat Sci Educ. 7: 47–55. © 2013 American Association of Anatomists.     

A Comparison of Item-Selection Methods for Adaptive Tests with Content Constraints

In test assembly, a fundamental difference exists between algorithms that select a test sequentially or simultaneously. Sequential assembly allows us to optimize an objective function at the examinee's ability estimate, such as the test information function in computerized adaptive testing. But it leads to the non-trivial problem of how to realize a set of content constraints on the test—a problem more naturally solved by a simultaneous item-selection method. Three main item-selection methods in adaptive testing offer solutions to this dilemma. The spiraling method moves item selection across categories of items in the pool proportionally to the numbers needed from them. Item selection by the weighted-deviations method (WDM) and the shadow test approach (STA) is based on projections of the future consequences of selecting an item. These two methods differ in that the former calculates a projection of a weighted sum of the attributes of the eventual test and the latter a projection of the test itself. The pros and cons of these methods are analyzed. An empirical comparison between the WDM and STA was conducted for an adaptive version of the Law School Admission Test (LSAT), which showed equally good item-exposure rates but violations of some of the constraints and larger bias and inaccuracy of the ability estimator for the WDM.     

Socialisation into organised sports of young adolescents with a lower socio-economic status

Studies investigating sport socialisation often focussed on the barriers for youngsters from lower socio-economic status (SES) families to participate in sport. In the present study, the socialisation into sports of young adolescents from lower SES families that do participate in organised sports was investigated. A total of 9 girls and 12 boys from lower SES families (18 Dutch; three foreign ethnic background) from one city in the Netherlands who participated in organised sport were interviewed. Although multiple agents may be of influence on the socialisation process, this study was limited to the family, school and peers as potential socialising contexts. Drawing on the theoretical work of Bourdieu and Bernstein, parents were found to be the main influencers of the sports habitus of these young adolescents. The school context appeared to have no influence on their sport socialisation. Peers were found to have an influence on the choice for a specific type of sport. This interplay between socialising contexts for young adolescents from lower SES families is similar to the sport socialisation of youngsters from higher SES families. Therefore, it is suggested that if sport socialisation takes place, then the role of SES is less pronounced than often assumed. Moreover, there seem to be differences in the relative importance of the socialising contexts with younger children with a lower SES. Therefore, it is hypothesised that the relative importance of socialising agents changes over time. Although the findings may be limited to the specific sample of this study, they provide hypotheses that challenge the often-presumed importance of SES if sport socialisation takes place.     

What’s in a name: dimensions of social learning in teacher groups

Induced by a literature review, this paper presents a framework of dimensions and indicators highlighting the underpinning aspects and values of social learning within teacher groups. Notions of social networks, communities of practice and learning teams were taken as the main perspectives to influence this social learning framework. The review exercise resulted in four dimensions: (1) practice, (2) domain and value creation, (3) collective identity and (4) organization. The indicators corresponding to these dimensions serve as the foundation for understanding social learning in practice. The framework of dimensions and indicators can be of assistance for researchers as well as teacher groups that aim to assess their views on social learning and analyse whether these views fit the learning goals of the group or that adjustments are required. In this way, learning processes within groups of teachers can be improved.     

A physically active lifestyle is related to a lower level of skin autofluorescence in a large population with chronic-disease (LifeLines cohort)

Background:Physical activity(PA)has substantial health benefits and is important in combatting chronic diseases,which have been associated with elevated levels of advanced glycation endproducts(AGEs).AGEs play a role in the aging process,and an association between PA and AGEs has been reported.We aimed to investigate the relationship between PA and AGE accumulation in a general population and in a population with chronic diseases.Methods:This large cross-sectional population study used data from adult participants in the LifeLines project,with participant information drawn from the LifeLines database as well data from patients with diabetes mellitus or renal and/or cardiovascular diseases.Tissue AGE accumulation was assessed non-invasively by skin-autofluorescence(SAF)using an AGE reader(DiagnOptics Technologies BV,Groningen,the Netherlands).PA was assessed using the short questionnaire to assess health-enhancing physical activity(SQUASH).Multivariate linear regression analyses were adjusted for age,body mass index,sex,and smoking status.Results:Data from 63,452 participants(general population n=59,177,chronic disease n=4275)were analyzed.The general population was significantly younger(43.58±11.77 years,mean±SD)and had significantly lower SAF(1.90±0.42 arbitrary units(AU))compared to the population with chronic disease(age:55.51±12.07 years;SAF:2.27±0.51 AU).In the group with chronic disease,more hours of moderate to vigorous physical activities per week were associated with lower SAF(β=-0.002,95%confidence interval(95%CI):-0.002 to-0.001).For the general population,there was no association between hours of moderate to vigorous activity and SAF(β=3.2×10^-5,95%CI:0.000-0.001,p=0.742).However,there was an association in the general population between total hours of PA per week and SAF(β=4.2×10^-4,95%CI:0.000-0.001,p<0.001),but this association was not found in the chronic disease population(β=-3.2×10^-4,95%CI:-0.001 to 0.000,p=0.347).Conclusion:Our study demonstrates that an inverse relationship exists between PA and AGE accumulation in the population with chronic disease.More hours of moderate to vigorous activity is associated a significantly decreased SAF.More PA is associated a lower SAF,even after for the established predictors(age,body mass index,smoking status,and sex).Our findings could help to promote health and prolong longevity.     

David F. Treagust: congenial soul, science educator, and international research leader

For almost a half century David F. Treagust has been an exemplary science educator who has contributed through his dedication and commitments to students, curriculum development and collaboration with teachers, and cutting edge research in science education that has impacted the field globally, nationally and locally. A hallmark of his outstanding career is his collaborative style that inspires others to produce their best work.     

The practical paradox of technology: The influence of communication technology use on employee burnout and engagement

Technological advancements in the workplace frequently have produced contradictory effects by facilitating accessibility and efficiency while increasing interruptions and unpredictability. We combine insights from organizational paradoxes and the job demands–resources model to construct a framework identifying positive and negative mechanisms in the relationship between communication technology use (CTU) and employee well-being, operationalized as work engagement and burnout. In this study of Dutch workers, we demonstrate that CTU increases well-being through positive pathways (accessibility and efficiency) and decreases well-being through negative pathways (interruptions and unpredictability). We highlight the importance of (1) investigating CTU resources and demands simultaneously to grasp the relationship between CTU and employee well-being, and (2) considering CTU's downsides to successfully implement new communication technologies and flexible work designs.