The role of output speech in literacy acquisition: Evidence from congenital anarthria

A case study of literacy acquisition in acongenitally speechless child (SM) isreported. In spite of a complete oral apraxia(due to bilateral focal brain damage), SMdeveloped normal intelligence and acquired complete mastery of reading and writing skills.Furthermore, both his verbal memory andmetaphonological skills were surprisinglypreserved. However, he showed a relativeimpairment in writing non-words. Theimplications of these findings for thedevelopmental interactions between language andliteracy are discussed.     

The Emergence of Cognitive Maps for Spatial Navigation in 7- to 10-Year-Old Children

Although much is known about adults’ ability to orient by means of cognitive maps (mental representations of the environment), it is less clear when this important ability emerges in development. In the present study, 97 seven- to 10-year-olds and 26 adults played a video game designed to investigate the ability to orient using cognitive maps. The game required participants to reach target locations as quickly as possible, necessitating the identification and use of novel shortcuts. Seven- and 8-year-olds were less effective than older children and adults in using shortcuts. These findings provide clear evidence of a distinct developmental change around 9 years of age when children begin to proficiently orient and navigate using cognitive maps.     

The grace period in international patent law and its effect on the timing of disclosure

The paper applies a novel methodology to US and EPO patent data to assess how often the “general grace period” exception is used in the USA and the likely impact of international patent regulations that almost invariably deny such use on the pace of new disclosures in academia. Comparisons of average publication delays of European academic inventors show that the grace period accelerates knowledge communication and that variations are likely to depend on a lack of harmonisation of international legal systems, transaction costs and the presence of a firm among patent assignees.     

A Critical Analysis of Current Indexes for Digital Divide Measurement

Several composite indexes grouping several variables into a single figure have been proposed for measuring the digital divide. In this article, the authors analyze shortcomings of extant indexes. Using multivariate analysis tools, they show that in the definition of composite indexes it is possible to individuate a limited set of more influencing and significant variables. This finding suggests the possibility of replacing some redundant variables with other dimensions that include other aspects of the digital divide that are not considered in extant measures.     

The effect of boot stiffness on field and laboratory flexural behavior of alpine ski boots

The aim of this work was to study the effect of boot stiffness on the field and laboratory flexural behavior of alpine ski boots. Ski boots have a direct influence on performance, safety, and comfort of alpine skiers. Despite their technological evolution during a number of years, the parameters used in the evaluation of boot stiffness are not yet standardized and still require a shared engineering approach to achieve common quantitative definitions to be used either in boot classification or in boot selection for the different users. This work reports the boot flexion angles between shell and cuff and between cuff and tibia, collected during slalom tests on three boots with different nominal Flex Index. The laboratory data collected on the same boots under conventional cyclic bending tests are reported and compared with the field data for the development of a new test method more representative of the field behavior. As a result, clear definitions of Flex Index and of boot stiffness are introduced: boot stiffness had a clear effect on both the field and the laboratory flexural behavior of boots.     

Funding higher education and wage uncertainty: Income contingent loan versus mortgage loan

We propose a simple theoretical model which shows how the combined effect of wage uncertainty and risk aversion can modify the individual willingness to pay for a HE system financed by an ICL or a ML. We calibrate our model using real data from the 1970 British Cohort Survey together with the features of the English HE financing system. We allow for individual heterogeneity by considering different family backgrounds and occupations. We find that graduates from poor families, males and graduates working in the private sector are more willing to pay to switch to an ICL. Using the UK Labour Force Survey we evaluate the distributive effects of our model. We compute the repayment burdens and taxpayer subsidies for average, low and high earnings graduates. The results confirm the important insurance benefits of an ICL compared to a ML, with lower burdens and higher subsidies for poorer graduates.     

Developing an audiovisual notebook as a self‐learning tool in histology: Perceptions of teachers and students

Videos can be used as didactic tools for self‐learning under several circumstances, including those cases in which students are responsible for the development of this resource as an audiovisual notebook. We compared students' and teachers' perceptions regarding the main features that an audiovisual notebook should include. Four questionnaires with items about information, images, text and music, and filmmaking were used to investigate students' (n = 115) and teachers' perceptions (n = 28) regarding the development of a video focused on a histological technique. The results show that both students and teachers significantly prioritize informative components, images and filmmaking more than text and music. The scores were significantly higher for teachers than for students for all four components analyzed. The highest scores were given to items related to practical and medically oriented elements, and the lowest values were given to theoretical and complementary elements. For most items, there were no differences between genders. A strong positive correlation was found between the scores given to each item by teachers and students. These results show that both students' and teachers' perceptions tend to coincide for most items, and suggest that audiovisual notebooks developed by students would emphasize the same items as those perceived by teachers to be the most relevant. Further, these findings suggest that the use of video as an audiovisual learning notebook would not only preserve the curricular objectives but would also offer the advantages of self‐learning processes. Anat Sci Educ 7: 209–218. © 2013 American Association of Anatomists.     

The use of S-Monovette is effective to reduce the burden of hemolysis in a large urban emergency department

Background

Due to the high prevalence of hemolysis in specimens received from the emergency department (ED), several strategies have been proposed to improve sample quality, but none of these seem effective to overcome the problem. In a preliminary study we showed that the use of S-Monovette blood collection system was effective to lower the risk of hemolysis in venous blood samples collected from intravenous catheters. This study was hence aimed to verify whether the replacement of a conventional vacuum system with S-Monovette may be effective to reduce the burden of hemolysis in the daily practice of a large urban ED.

Materials and methods

The study was divided in two observational periods of 4 months each. In the former period, blood was collected from intravenous catheters using BD Vacutainer SST II Plus plastic serum tubes, whereas in the latter period the blood was drawn from intravenous catheters using S-Monovette blood tubes in aspiration mode. Sample hemolysis was automatically assessed in all serum samples by photometrical measurement.

Results

The total number of hemolysed serum specimens was 624/14155 (4.41%) in the first phase of the study, and 342/13319 (2.57%) in the second phase of the study (P < 0.001).

Conclusion

Results of our study confirm that the introduction of the Sarstedt S-Monovette blood tubes has reduced the hemolysis rate in the emergency department compared to the previously used BD Vacutainer® SST II Plus plastic serum tubes.Key words: preanalytical phase, hemolysis, blood specimen collection, catheter, emergency department     

Incorrect order of draw could be mitigate the patient safety: a phlebotomy management case report

Procedures involving phlebotomy are critical for obtaining diagnostic blood specimens and represent a well known and recognized problem, probably among the most important issues in laboratory medicine. The aim of this report is to show spurious hyperkalemia and hypocalcemia due to inadequate phlebotomy procedure. The diagnostic blood specimens were collected from a male outpatient 45 years old, with no clinical complaints. The tubes drawing order were as follows: i) clot activator and gel separator (serum vacuum tube), ii) K₃EDTA, iii) a needleless blood gas dedicated-syringe with 80 I.U. lithium heparin, directly connected to the vacuum tube holder system. The laboratory testing results from serum vacuum tube and dedicated syringe were 4.8 and 8.5 mmol/L for potassium, 2.36 and 1.48 mmol/L for total calcium, respectively. Moreover 0.15 mmol/L of free calcium was observed in dedicated syringe. A new blood collection was performed without K₃EDTA tube. Different results were found for potassium (4.7 and 4.5 mmol/L) and total calcium (2.37 and 2.38 mmol/L) from serum vacuum tube and dedicated syringe, respectively. Also free calcium showed different concentration (1.21 mmol/L) in this new sample when compared with the first blood specimen. Based on this case we do not encourage the laboratory managers training the phlebotomists to insert the dedicated syringes in needle-holder system at the end of all vacuum tubes. To avoid double vein puncture the dedicated syringe for free calcium determination should be inserted immediately after serum tubes before EDTA vacuum tubes.