试论太极拳抗衰老的机理

太极拳在扶植体内正气,疏通气机,引气活血,舒活筋骨,营养精神方面是优于其他体育项目的,对中、老年人或病患者来说,更是如此,这种动静结合的太极拳确是扶正祛邪,防病健身,抵抗衰老,延年益寿的良剂佳药．     

抓好课程建设 提高研究生培养质量

讨论了如何科学地位置研究生学位课程,使之具有合理、宽广的知识结构,同时在教学内容、教学方法上提出了改进意见。     

知识产权保护与信息产权

1信息保护的新问题 知识产权是指人们在科学、技术、文化艺术等领域内基于智力的创造性活动而享有的权力.传统的知识产权主要包括专利权、商标权与著作权(版权).知识产权涉及大量的科技信息(如技术秘密、专利)、文化信息(著作权)、经济贸易信息(如专利、商标、商业秘密)等,这是知识产权保护客体本身所具有的.     

浅谈数学建模

对数学建模的概念及如何进行数学建模进行了比较详尽的叙述。     

Dynamic resistance exercise increases skeletal muscle-derived FSTL1 inducing cardiac angiogenesis via DIP2A–Smad2/3 in rats following myocardial infarction

PurposeThe aim of this study was to investigate the potential of dynamic resistance exercise to generate skeletal muscle-derived follistatin like-1 (FSTL1), which may induce cardioprotection in rats following myocardial infarction (MI) by inducing angiogenesis.MethodsMale, adult Sprague-Dawley rats were randomly divided into 5 groups (n = 12 in each group): sham group (S), sedentary MI group (MI), MI + resistance exercise group (MR), MI + adeno-associated virus (AAV)–FSTL1 injection group (MA), and MI + AAV–FSTL1 injection + resistance exercise group (MAR). The AAV–FSTL1 vector was prepared by molecular biology methods and injected into the anterior tibialis muscle. The MI model was established by ligation of the left anterior descending coronary artery. Rats in the MR and MAR groups underwent 4 weeks of dynamic resistance exercise training using a weighted climbing-up ladder. Heart function was evaluated by hemodynamic measures. Collagen volume fraction of myocardium was observed and analyzed by Masson''s staining. Human umbilical vein vessel endothelial cells culture and recombinant human FSTL1 protein or transforming growth factor-β receptor 1 (TGFβR1) inhibitor treatment were used to elucidate the molecular signaling mechanism of FSTL1. Angiogenesis, cell proliferation, and disco interacting protein 2 homolog A (DIP2A) location were observed by immunofluorescence staining. The expression of FSTL1, DIP2A, and the activation of signaling pathways were detected by Western blotting. Angiogenesis of endothelial cells was observed by tubule experiment. One-way analysis of variance and Student''s t test were used for statistical analysis.ResultsResistance exercise stimulated the secretion of skeletal muscle FSTL1, which promoted myocardial angiogenesis, inhibited pathological remodeling, and protected cardiac function in MI rats. Exercise facilitated skeletal muscle FSTL1 to play a role in protecting the heart. Exogenous FSTL1 promoted the human umbilical vein vessel endothelial cells proliferation and up-regulated the expression of DIP2A, while TGFβR1 inhibitor intervention down-regulated the phosphorylation level of Smad2/3 and the expression of vascular endothelial growth factor-A, which was not conducive to angiogenesis. FSTL1 bound to the receptor, DIP2A, to regulate angiogenesis mainly through the Smad2/3 signaling pathway. FSTL1–DIP2A directly activated Smad2/3 and was not affected by TGFβR1.ConclusionDynamic resistance exercise stimulates the expression of skeletal muscle-derived FSTL1, which could supplement the insufficiency of cardiac FSTL1 and promote cardiac rehabilitation through the DIP2A–Smad2/3 signaling pathway in MI rats.     

高炉模块式炉身温度场的研究

应用有限单元法对模块式炉身温度场进行区域离散,对乌克兰大型模块式炉身各截面在不同边界条件下的二维温度场分布进行了计算,得到各特征截面二维温度场分布图。证明模块式炉身温度场分布合理,其利用渣皮工作的原理是可行的;论证了乌克兰设计中冷却水管间距、冷却水流速、管径及水温取值的依据。     

Maternal Reminiscing and Autobiographical Memory Features of Mother–Child Dyads in a Cross-Cultural Context

Maternal reminiscing styles and mother–child memory features were examined in a cross-cultural context. Fifty-five Chinese (Guangzhou, China) and 48 Australian (Melbourne, Australia) mother–child dyads (child age: 3–6 years) independently retrieved autobiographical memories and jointly discussed past events. Australian mothers used greater elaborative and supportive reminiscing and provided more specific memories than Chinese mothers. Australian children provided greater memory elaboration than Chinese children, but they did not differ in memory specificity. Maternal reminiscing styles and cultural group were independently predictive of child memory elaboration but not specificity. Nonetheless, moderation analyses showed that the two maternal reminiscing styles (elaborative and supportive) interacted to predict child memory specificity. These findings indicate the importance of culture and types of reminiscing on memory development.     

国际化科研环境建设亟待解决的若干堵点剖析及政策建议

加强国际化科研环境建设有助于促进国际科技交流合作,构建具有全球竞争力的开放创新生态。文章基于调研访谈和政策分析,剖析了我国在科研人员出国（境）、科学数据跨境流动、科研物资出入境、科技计划对外开放、国际科技组织来华、外国人才服务保障6个方面的堵点并提出政策建议。研究表明,我国国际化科研环境建设存在科技创新体系开放不足、配套政策存在空白等问题,导致创新资源跨境流动不畅,影响全球创新资源的有效集聚。这些问题的根源既在于政策和制度本身的系统性不足,也与政策出台后落地不实、知晓度不够、手续繁琐等有关。建议从加强顶层设计、完善法律法规、强化部门协同、优化政策规定、简化程序和手续、细化操作指导等方面入手,打通人员、数据、物资、资金等跨境流动堵点,以构建更具竞争力的科技创新开放合作制度环境。     

《计算机专业英语》探析教学

针对大学<计算机专业英语>课程的特点和目前在该课程教学过程中存在的若干问题,本文从实践的角度出发,探索了在大学<计算机专业英语>教学过程中的教学法的改革,以及教学内容的改革.实践证明改革得到了较好的教学效果.