生物化学综合性实验的探索与评价

以河北科技师范学院2005级生物科学、生物技术专业学生为样本,通过对生物化学综合性实验效果的调查,说明综合性实验在突出学生主体地位、激发学生兴趣等方面起到了积极的作用,能够在培养学生团队合作精神、科研能力等多方面综合能力的提升。     

扩招背景下提高实践教学质量的方法研究与实践

探讨了扩招背景下工程训练实践教学面临的机遇和挑战,对工程训练中提高教学质量的方法和途径进行了研究,提出了通过构建工程训练体系、实践教学保障体系和考核评价体系提高实践教学质量的思路,并结合整个教学团队的工作实践,阐述了在实践教学中的应用情况.     

Replication,pathogenicity, and transmission of SARS-CoV-2 in minks

Minks are raised in many countries and have transmitted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to humans. However, the biologic properties of SARS-CoV-2 in minks are largely unknown. Here, we investigated and found that SARS-CoV-2 replicates efficiently in both the upper and lower respiratory tracts, and transmits efficiently in minks via respiratory droplets; pulmonary lesions caused by SARS-CoV-2 in minks are similar to those seen in humans with COVID-19. We further found that a spike protein-based subunit vaccine largely prevented SARS-CoV-2 replication and lung damage caused by SARS-CoV-2 infection in minks. Our study indicates that minks are a useful animal model for evaluating the efficacy of drugs or vaccines against COVID-19 and that vaccination is a potential strategy to prevent minks from transmitting SARS-CoV-2.     

利用校本课程加强民族传统文化教育

传统文化是一个民族的精神支柱和源泉。本文从政治、文化和经济的角度分析加强传统文化教育的必要性,并提出民族学校开发校本课程加强少数民族传统文化教育的措施。     

论社会弱势群体的成因及其扶助措施

弱势群体问题关系着社会稳定的大局,已成为时下中国社会关注的热点问题。本文客观剖析了弱势群体产生的原因,提出了扶助社会弱势群体的具体措施。     

开封城市家庭日常出行碳排放空间分异研究

在气候变化和快速城镇化的背景下可持续交通问题日益受到重视。本文借助大样本调查数据和高分辨率遥感影像,以城市快速扩张的典型中小城市河南开封市为研究区域,采用ESDA、GWR等空间统计和分析方法探索城市内部家庭出行碳排放空间差异及影响因素。结果表明：① 开封市家庭出行碳排放的高值集聚区大多分布于城市的外圈层,在一定程度上验证了城市蔓延对居民出行碳排放增加的驱动效应;② 家庭出行碳排放的局部空间差异反映出城市快速扩张区域新建商品房小区职住分离、公共服务供给与城市发展不匹配的现象,以及城市发展缓慢区域大型购物场所等便民服务设施缺失等问题;③ 家庭出行碳排放的不均衡性明显,但收入水平并非决定因素,小汽车的拥有量、出行距离、出行频率以及机动车出行比重对其有显著的正向影响,其中教育出行距离比职住距离影响更甚,说明伴随着家庭对教育的不断重视,优质教育资源的不均衡发展有待改善;④ 除男主人出行频率对出行碳排放的影响空间破碎化程度较高外,其余影响因素的作用强度均明显存在与城市发展的主要方向相一致的东西带状渐变的空间分布规律。     

发展中国电子商务的几点思考

“电子商务”这个名词在我国已经不在是陌生的名词了,它已经在中国越来越被人们所认可.什么是电子商务?所谓电子商务(ElectronicCommerce)是利用计算机技术、网络技术和远程通信技术,实现整个商务(买卖)过程中的电子化、数字化和网络化。人们不再是面对面的、看着实实在在的货物、靠纸介质单据(包括现金)进行买卖交易。而是通过网络,通过网上琳琅满目的商品信息、完善的物流配送系统和方便安全的资金结算系统进行交易(买卖)。     

Genomic diversity and post-admixture adaptation in the Uyghurs

Population admixture results in genome-wide combinations of genetic variants derived from different ancestral populations of distinct ancestry, thus providing a unique opportunity for understanding the genetic determinants of phenotypic variation in humans. Here, we used whole-genome sequencing of 92 individuals with high coverage (30–60×) to systematically investigate genomic diversity in the Uyghurs living in Xinjiang, China (XJU), an admixed population of both European-like and East-Asian-like ancestry. The XJU population shows greater genetic diversity, especially a higher proportion of rare variants, compared with their ancestral source populations, corresponding to greater phenotypic diversity of XJU. Admixture-induced functional variants in EDAR were associated with the diversity of facial morphology in XJU. Interestingly, the interaction of functional variants between SLC24A5 and OCA2 likely influences the diversity of skin pigmentation. Notably, selection has seemingly been relaxed or canceled in several genes with significantly biased ancestry, such as HERC2–OCA2. Moreover, signatures of post-admixture adaptation in XJU were identified, including genes related to metabolism (e.g. CYP2D6), digestion (e.g. COL11A1), olfactory perception (e.g. ANO2) and immunity (e.g. HLA). Our results demonstrated population admixture as a driving force, locally or globally, in shaping human genetic and phenotypic diversity as well as in adaptive evolution.     

论师资结构对高校体育教育可持续发展的影响

文章运用文献资料法、调查法和数理统计法,通过对甘肃高校公共体育课开设状况及特点、教师比例、学历、职称、年龄结构、教学能力和科研能力等现状的调查与分析.提出了通过增加教师数量,稳定教师队伍,提高教师素质等促进学校体育工作发展的措施.     

冰上杂技音乐剧 《爱丽丝梦游仙境》的审美体现

大型冰上杂技音乐剧《爱丽丝梦游仙境》是由黑龙江冰尚杂技舞蹈演艺制作有限公司与融创集团联袂推出的一部精品力作。该剧根据英国童话大师刘易斯·卡罗尔的《爱丽丝漫游仙境》和《爱丽丝镜中奇遇记》及迪士尼以此素材拍摄的3D电影改编而成。经过剪头绪、立主脑,简化了原著的故事情节和人物关系。