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51.
Daniel A. Bizjak Fabian Tomschi Gunnar Bales Elie Nader Marc Romana Philippe Connes Wilhelm Bloch Marijke Grau 《运动与健康科学(英文)》2020,9(6):595-603
ObjectiveTo examine the impact of a 6-week endurance training on red blood cell (RBC) aging and deformability of healthy participants to detect possible improved hemorheological and performance-related adaptations.MethodsA total of 31 participants (17 females and 14 males) performed a 6-week moderate training protocol (three 1-h running sessions per week at 70% of maximal heart rate). Blood was sampled before and after the training. RBCs from each participant were fractioned according to density and age into 4 RBC subfractions. Subfractions were examined for changes of RBC properties, including aging distribution, RBC deformability, RBC microparticles, and phosphatidylserine concentrations. RBC and plasma nitrite levels were measured as indicators of nitric oxide metabolism.ResultsAerobic performance, peak oxygen consumption, ventilatory thresholds, velocity at the aerobic–anaerobic threshold, and lactate at exhaustion improved after training. The relative amount of both young RBCs and old RBCs increased, and the amount of the main RBC fraction decreased. Phosphatidylserine externalization and RBC-derived microparticles decreased. Overall deformability expressed as shear stress required to achieve half-maximum deformation to theoretical maximal elongation index at infinite shear stress improved in unfractioned RBCs (p < 0.001). Nitrite decreased in total (p = 0.001), young (p < 0.001), main (p < 0.001), and old (p = 0.020) aged RBCs and in plasma (p = 0.002), but not in very old RBCs.ConclusionThese results indicate that non-endurance-trained healthy participants benefit from a regular moderate running training program because performance-related parameters improve and a younger RBC population with improved RBC properties is induced, which might support oxygen supply in the microcirculation. 相似文献
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53.
Evening activities as a potential confound in research on the adrenocortical system in children 总被引:2,自引:0,他引:2
The relation among children's evening activities, behavioral characteristics, and activity of the hypothalamic-pituitary-adrenocortical axis was assessed in normally developing children ages 7 to 10 years. Salivary cortisol at bedtime was compared on evenings when children had structured activities outside of the home with unstructured evenings at home in relation to parental reports of children's behavioral characteristics. Participating in evening activities, particularly sport activities, was associated with small increases in bedtime cortisol levels in boys but not in girls. Differences in cortisol on activity versus no-activity nights were negatively related to children's social isolation. These results show that in studies with children, nights on which participants engage in sport activities should be avoided when collecting ambulatory measures of salivary cortisol concentrations. 相似文献
54.
Dampening of Adrenocortical Responses during Infancy: Normative Changes and Individual Differences 总被引:6,自引:0,他引:6
Changes in cortisol and behavioral responses were examined longitudinally in 83 infants (39 girls, 44 boys) tested at their well-baby exams with inoculations at 2, 4, 6, and 15 months (72 infants completed all testing). Another sample of 2-, 4-, and 6-month-olds ( n = 18 per age) received mock exams without inoculations to determine early developmental changes to the exam procedures. Behavioral distress was coded every 30 sec during the exam, a 5-min inoculation period, and a 20-min recovery period. Salivary cortisol was obtained upon arrival at the clinic and 25 min after the beginning of the inoculation period. To the exam-inoculation procedures, cortisol responses were high at 2 months, decreased significantly between 2 and 4 months, remained comparable between 4 and 6 months, and then declined again between 6 and 15 months. Between 6 and 15 months there was also a decrease in pretest cortisol. By 15 months, significant increases in cortisol from pre- to posttest were no longer observed for most infants. To the exam-only procedures, cortisol responses decreased between 2 and 4 months, and by 4 months most infants failed to show pre- to posttest increases in cortisol. Behavioral distress decreased between 2 and 6 months, but increased again at 15 months. While crying and cortisol were modestly correlated during the 2- to 6-month exam-inoculation procedures, at 15 months no significant correlations were obtained. Behavioral and hormonal reactions thus followed different ontogenetic paths and may provide different information about infant functioning. There was some evidence that the emergence of the circadian rhythm in cortisol might be related to the early decrease in cortisol response. 相似文献
55.
Gunnar?SchedinEmail author 《International journal for the advancement of counseling》2005,27(1):57-69
Expectations and experiences of the interpersonal behaviour between the counselor and the client were investigated in an exploratory study, and related to the evaluation of career counseling sessions with adolescents in a secondary school context in Sweden. The relationship was measured by using the Structural Analysis of Social Behaviour model (SASB). In general, positive evaluation as judged by the clients was found to be related to the clients having more positive expectations and experience of their own and counselors affiliative behaviour. No positive associations between own expected and experienced behaviour and evaluation were found as judged by the counselors. Affiliative behaviour was found to be the most important dimension in predicting evaluation of sessions in a positive way for the clients. 相似文献
56.
Coping with aversive stimulation in the neonatal period: quiet sleep and plasma cortisol levels during recovery from circumcision 总被引:2,自引:0,他引:2
Measures of behavioral state and plasma cortisol were obtained on 80 healthy, full-term, 2-3-day-old, male newborns who were scheduled to be circumcised. To establish baseline or precircumcision levels, the newborns were observed, and behavioral state was recorded for the half hour prior to circumcision. Blood was sampled via heelstick for plasma cortisol determination at the end of this observation period. The newborns were then circumcised and assigned randomly to one of 4 postcircumcision, blood-sampling time-point groups. The time points were 30, 90, 120, and 240 min following the beginning of circumcision. Behavioral state was observed during circumcision and for the half hour prior to taking the second blood sample. The results showed a return to baseline cortisol levels sometime prior to 240 min, with data from an additional group of 10 newborns indicating that the return occurred by 150 min. Behavioral distress during circumcision was associated with elevations in plasma cortisol at 30 and 90 min. Quiet sleep was correlated negatively with plasma cortisol prior to circumcision, and significant increases in quiet sleep followed circumcision, with the greatest increase corresponding to the period of most rapid reductions in cortisol. 相似文献
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58.
Gunnar Repp 《Journal of Adventure Education & Outdoor Learning》2004,4(2):117-131
With the ambition of penetrating into the very core of the Norwegian and Nordic friluftsliv: An ecologically responsible life in the open air-in nature, people will have to become acquainted with Fridtjof Nansen—with the thinker as well as the practitioner. Outdoor life with natural and strong links to the national friluftsliv—tradition was his ideal, and quite a lot of people in the years after him have been fired with his enthusiasm for the wonderful experiential and health—giving meetings with nature. Obviously, he has been a hero and an idol for generations of people. His reputation as an arctic explorer, as scientist and sportsman, as an internationalist and a humanitarian, have been emphasized by a great many books and articles about him. The main purpose of this article is to shed more light upon his thinking about friluftsliv, to show and explain its focus, its models and paragons. 相似文献
59.
Behavioral Inhibition and Stress Reactivity: The Moderating Role of Attachment Security 总被引:9,自引:1,他引:9
Melissa Nachmias Megan Gunnar Sarah Mangelsdorf Robin Hornik Parritz Kristin Buss 《Child development》1996,67(2):508-522
The role of the mother-toddler attachment relationship in moderating the relations between behavioral inhibition and changes in salivary cortisol levels in response to novel events was examined in 77 18-month-olds. Behavioral inhibition was determined by observing toddler inhibition of approach to several novel events. Attachment security to mother was assessed using the Ainsworth Strange Situation. Changes in salivary cortisol were used to index activity of the stress-sensitive hypothalamic-pituitary-adrenocortical (HPA) system. In addition, toddler coping behaviors and the behaviors used by mothers to help toddlers manage novel events were examined. Elevations in cortisol were found only for inhibited toddlers in insecure attachment relationships. Mothers in these relationships appeared to interfere with their toddlers' coping efforts. These results are discussed in the context of a coping model of the relations between temperament and stress reactivity. 相似文献
60.