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31.
Prospective application of serum cytokines, lipopolysaccharide (LPS), and heat shock proteins (eHSPs) requires reliable measurement of these biomarkers that can signify exercise-induced heat stress in hot conditions. To accomplish this, both short-term (7 day) reliability (at rest, n = 12) and the acute responsiveness of each biomarker to exercise in the heat (pre and post 60-min cycling, 34.5°C and 70% RH, n = 20) were evaluated. Serum was analysed for the concentration of C-reactive protein (CRP), interleukin-6 (IL-6), heat shock protein 72 (eHSP72), immunoglobulin M (IgM) and LPS. Test–retest reliability was determined as the coefficient of variation (CV). Biomarkers with the least short-term within-participant variation were IL-6 (19%, ±20%; CV, ±95% confidence limits (CL)) and LPS (23%, ±13%). Greater variability was observed for IgM, eHSP72 and CRP (CV range 28–38%). IL-6 exhibited the largest increase in response to acute exercise (95%, ±11%, P = < 0.001) and although CRP had a modest CV (12%, ±7%), it increased substantially post-exercise (P = 0.02, ES; 0.78). In contrast, eHSP72 and LPS exhibited trivial changes post-exercise. It appears variation of common inflammatory markers after exercise in the heat is not always discernible from short-term (weekly) variation.  相似文献   
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This article reports on research conducted as part of the Primary Science Processes and Concept Exploration (space) Project. The background to, and orientation of, space is briefly described.

Classroom‐based research into children's thinking about evaporation is reported. This work was conducted in close collaboration with teachers of the 5‐11 years age range with the intention of establishing the viability of the techniques for eliciting ideas and managing subsequent interventions within classrooms.

Children's thinking in relation to three main evaporation phenomena are discussed. Ideas about evaporation were categorized by reference to notions of conservation, change of location and change of form of the water.  相似文献   
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We present the process our institution used to create a statistics requirement for almost all incoming first‐year students. From conception and planning, to hiring and acceptance by the university community, we offer lessons learned should you consider making such a shift in your own curriculum.  相似文献   
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The globalization of the world's economy (and its labour market) reveals a growing need for graduate mobility. In this free global market, educational institutions are under increased pressure to show their intrinsic value, to define and guarantee their quality and to show continually their relevance to their communities and national governments (often the main financial stakeholder). Accreditation of degrees (and institutions) by a recognized international authority (or by an international network of recognized national authorities) is often quoted as the solution to address the needs of mobility and quality assurance. I believe that the process of accreditation is not the fundamental answer to these needs. Accreditation in education can be a stabilizing factor in a small-scale economical system, but it fails on a large (global) scale. The reason for this is that any accreditation scheme judges quality in an arbitrary way. The key to opening up free mobility of competencies and to leveraging quality education is to develop a system to measure objectively an individual's competence. A system that makes the abstract notion of 'competence' tangible to anyone, but that leaves the judgement open to the ones who need to judge…  相似文献   
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Research has shown that educational games can have positive impacts on student learning and motivation. The success of a game played in a library instruction class depends on the type of game selected, the development of learning outcomes, and the flexibility of the librarian during class. This article explains the benefits to students and librarians of using games, discusses the development and use of a Jeopardy-style game, and provides practical tips for librarians interested in developing and incorporating games into one-time library instruction sessions.  相似文献   
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