Use of NSE/PS2m-transgenic mice in the study of the protective effect of exercise on Alzheimer's disease

In its late stage, Alzheimer's disease results in progressive muscle weakness in the arms and legs. The aim of this study was to determine whether mice expressing the skeletal muscle-specific mutant PS2 gene (a model of Alzheimer's disease) are a useful experimental system to study the protective effect of exercise on Aβ-42 reduction, improvement of behavioural function and changes in metabolic parameters. With this aim in mind, the transgenic mice were subjected to treadmill exercise for 3 months. The results showed that in transgenic mice, but not in normal mice, treadmill exercise resulted in a reduction of Aβ-42 deposits and an improvement in behavioural function, thereby restoring normal concentrations of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and triglyceride. Thus, exercise may represent a practical therapeutic strategy for use with human patients with Alzheimer's disease.     

A study on the motivational aspects of information management practice

This research investigates the motivational aspects of information management practice by developing and performing an initial test of the theorization on the components and structural properties of a new variable, called information management motivation (IMM). Based on a synthesis of the motivation and information processing literature in the information systems, psychology, management, and information technology training fields, we theorize IMM as a second order construct composed of formative sub-constructs of proactiveness, sharing, transparency, and formality. New measures were developed for the constituent constructs of IMM and refined through two studies involving 120 knowledge workers. The model of IMM was tested, confirming the proposed structural relationships between the constituent constructs and IMM. The study findings provide important insights on understanding and improving individual knowledge workers’ information management activities.     

Crossing the Border: Religious Education of Coexistence with the Case of North Korean Refugees in the U.S

Abstract

When one decides to cross the border of a nation due to political oppression and poverty, it is a crucial decision for the whole world and time around them. Many people make the treacherous journey across economic systems and political and religious background to pursue human dignity and happiness. Among many refugee groups who cross such borders, my research pays attention to North Korean refugees in the United States and their settlement process. As North Korean refugees enter this land of freedom and prosperity, are they provided adequate aid and education to redirect their mindset from communism to capitalism, from oppression and trauma to living together? What is the role of the faith community and of religious education in it? Based on postcolonial feminist practical theology, this paper explores the journey together and offers a pedagogy of coexistence and mutual transformation.     

Investigating the effectiveness of a learning activity supported by a mobile multimedia learning system to enhance autonomous EFL learning in authentic contexts

A learning activity supported by a mobile multimedia learning system (MMLS) was designed in this study. We aimed to test the effectiveness of the learning activity to enhance autonomous language learning in quasi-experimental Study 1 using a pretest/posttest design. Two groups participated in the learning activity: the students in a control group (n = 27) completed the activity using traditional approach whereas the students in an experimental group (n = 26) completed the activity using MMLS. The results of Study 1 showed that the experimental students outperformed their counterparts on the post-test (F = 29.602, p < 0.005, partial eta-squared = 0.372). In a non-experimental Study 2, the experimental students (n = 26) were assigned two learning tasks, the first task was completed individually and the second task in collaboration. We aimed to investigate which learning approach to complete tasks (i.e. individual vs. collaborative) enhances learning performance better by comparing students’ scores on two tasks. In addition, we explored students’ perceptions towards MMLS. The results of Study 2 showed that the students had better learning performance when they completed tasks in collaboration than individually. The results also showed that the students had high perceptions towards MMLS. Based on our results, we make suggestions and provide directions for future research.     

Influence of an integrated learning diagnosis and formative assessment-based personalized web learning approach on students learning performances and perceptions

The advancement of computer and communication technologies has enabled students to learn across various real-world contexts with supports from the learning system. In the meantime, researchers have emphasized the necessity of providing personalized learning guidance or support by considering individual students’ status and needs in order to improve their learning performance. Based on this perspective, this study proposes a formative assessment-based approach for improving the learning performance of students in a personalized learning environment. An integrated learning diagnosis and formative assessment-based personalized web learning system was developed based on this approach. To evaluate the effectiveness of the proposed approach, an experiment was conducted in an elementary school mathematics course in Thailand. The experimental results showed that (1) the students learning with the proposed system revealed significantly better learning achievement and learning perceptions than those learning with the conventional learning system and (2) students’ learning perceptions of the system had significant relationships with their learning achievement.     

Learning science in an era of globalization: a phenomenology of the foreign/strange

In this study, we propose a set of concepts for conceptualizing issues of learning science related to globalization, the encounter with the (radically) foreign/strange—as this occurs as part of migration and even as part of the encounter of a learner with the unknown content that science lessons are to impart—from the perspective of the experiencing person and the experience. We take an approach to the question of the foreign/strange that is grounded in philosophies of difference, which have emerged in continental Europe, and which make use of advances in phenomenology, dialectics, and materialism. We draw on ethnographic work in one undergraduate physics course at a Canadian university, where we followed in particular one female Japanese student, who had come to this country for the purpose of getting a degree. As an entry point and as source of empirical materials, we draw on our own auto/ethnographic experience that brings particular advantages to ally pathos to the experience of the foreign/strange, something is happening to (affecting) us that is beyond all experience, understanding, and anticipation. We articulate three phenomenological aspects that pathos (empathy) allows us to understand concerning the experience of the foreign/strange and then provide an exemplary and exemplifying analysis.

Understanding and Changing Older Adults' Perceptions and Learning of Social Media

An exploratory study was conducted to answer the following questions: What are older adults' perceptions of social media? What educational strategies can facilitate their learning of social media? A thematic map was developed to illustrate changing perceptions from the initial unanimous, strong negative to the more positive but cautious and to the eventual willingness to actually contribute content. Privacy was the primary concern and key perceptual barrier to adoption. Effective educational strategies were developed to overcome privacy concerns, including: 1) introducing the concepts before introducing the functions; 2) responding to privacy concerns; and 3) making social media personally relevant.     

Development of a personalized educational computer game based on students’ learning styles

In recent years, many researchers have been engaged in the development of educational computer games; however, previous studies have indicated that, without supportive models that take individual students?? learning needs or difficulties into consideration, students might only show temporary interest during the learning process, and their learning performance is often not as good as expected. Learning styles have been recognized as being an important human factor affecting students?? learning performance. Previous studies have shown that, by taking learning styles into account, learning systems can be of greater benefit to students owing to the provision of personalized learning content presentation that matches the information perceiving and processing styles of individuals. In this paper, a personalized game-based learning approach is proposed based on the sequential/global dimension of the learning style proposed by Felder and Silverman. To evaluate the effectiveness of the proposed approach, a role-playing game has been implemented based on the approach; moreover, an experiment has been conducted on an elementary school natural science course. From the experimental results, it is found that the personalized educational computer game not only promotes learning motivation, but also improves the learning achievements of the students.     

亚里士多德实践哲学中的公民德育概念

在21世纪的今日,民主化成为世界潮流,尽管世界各国在民主化的实施方式、内容与进程上有很大的差异,但不可否认公民德育在推动并建构民主化社会的目标上有其关键的重要性。透过对亚里士多德伦理学与政治学文献的探讨,可以厘清原始公民德育的概念。亚里士多德在其所著《政治学》一书中对公民的定义与城邦的构成要素、公民教育与政体的关系、公民德育实践的必要性及其实施的内容与方法进行了阐述。尽管亚里士多德有关公民的概念与公民德育的理论太过粗略与朴素,还没有碰触到现代民主社会中复杂的权利与义务理念,但他把公民德育的培育当做政治哲学的理论核心却是充满超越时代的先知卓见。