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21.
We describe a microfluidic device for on-chip chemical processing, such as staining, and subsequent washing of cells. The paper introduces “separator walls” to increase the on-chip incubation time and to improve the quality of washing. Cells of interest are concentrated into a treatment stream of chemical reagents at the first separator wall for extended on-chip incubation without causing excess contamination at the output due to diffusion of the unreacted treatment chemicals, and then are directed to the washing stream before final collections. The second separator wall further reduces the output contamination from diffusion to the washing stream. With this approach, we demonstrate on-chip leukocyte staining with Rhodamine 6G and washing. The results suggest that other conventional biological and analytical processes could be replaced by the proposed device.  相似文献   
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This study investigated whether mathematics education based on a multi-tiered response to intervention (RTI) model can support students' arithmetic competence in primary schools in Sweden. The intent was to identify and support students at risk of failure. In this study, 113 students participated in the intervention, and 30 students participated in the control group. Both groups were followed from Grade 1 to the end of Grade 2 and compared. During the first semester in Grade 1, all students were taught basic addition and subtraction with explicit instructions in Tier 1. Those who did not respond to Tier 1 after one semester were provided support within Tier 2 during the second semester. The same was repeated in grade 2 and the students that did not respond to Tier 2 were supported within Tier 3. At the end of Grade 2, students in the intervention group performed significantly higher on the basic arithmetic competence in the number range 1–9 than the control group. No significant difference was found in a test measuring basic arithmetic competence in the number range 10–19. This study shows that using multi-tiered RTI might be sufficient to identify and support students at risk in early arithmetic competence.  相似文献   
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In societies experiencing or emerging from conflict, teachers often deliver educational programmes designed to build community cohesion. We report on research which examined teachers’ views of the implementation of a programme involving both face-to-face and online contact between pupils. Findings suggest that this blended approach is highly motivational, enhancing online work and relationship building. The research underlines the importance of the political, educational and historical context for work of this sort and the impact this has on the particular blend of online and face-to-face interaction. Implications for policymakers and teachers include value for money and sustainability of blended intercultural education in similar contexts.  相似文献   
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This longitudinal study investigated the cross-lagged associations between children’s academic skill development, task-avoidant behaviour in the context of homework, and parental beliefs about their child’s success from kindergarten to Grade 2. The participants were 1267 children. The children’s pre-skills were assessed at the end of the kindergarten year, and math and reading skills at the end of Grade 1 and Grade 2. Parents provided ratings of their beliefs about their children’s school success and task-avoidant behaviour with regard to homework at the end of Grades 1 and 2. The results showed that children’s math and reading skills predicted children’s task-avoidant behaviour regarding homework as rated by mothers, but not by fathers, when autoregressive effects were taken into account. In addition, task-avoidant behaviour predicted the mothers’ subsequent beliefs about their children’s school success but not vice versa. A reciprocal effect was found between fathers’ beliefs about success and children’s task-avoidance.  相似文献   
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A number of studies have concluded that when students have greater confidence about their math skills and are aware of its usefulness, they have a more positive perception of the subject. This article aims to examine whether this pseudo linear trend in the relationship between affective and instrumental dimensions is also true of the university context. Special attention is devoted to the articulation of these dimensions in structuring student perceptions of quantitative methods so as to identify the various forms that this interaction can assume. Our second aim is to understand how the perceptions of these subjects are constructed by students from degree courses in distinct scientific areas. Can we speak of group dynamics whereby socialization within each degree course triggers the sharing of similar perceptions? We concluded that a certain linear trend can also be identified in the university context in the relationship between the affective dimension and usefulness of quantitative methods i.e., that the highest levels in the perception of the usefulness of these subjects corresponded to the highest levels of self confidence and enjoyment of the subjects. However, in addition to this scenario there is another configuration in which negative feelings coexist with the recognition of the usefulness of quantitative methods subjects. Namely, lower levels of self confidence and enjoyment of these subjects can also be associated with high levels of perceived usefulness. We also concluded that there is evidence of what we designated a certain course culture in the perceptions about quantitative methods. Nevertheless, when our observation is extended to the scientific area the heterogeneity of the perceptions becomes evident. Another important finding is the rejection of the thesis, at least in the university context, that defends the lack of self-confidence in quantitative methods among females student.  相似文献   
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The study examined the predictive value of adolescents’ personality trait ratings by different groups of informants in explaining academic achievement [grade point average (GPA)] while controlling for students’ sex and their mothers’ education. The Inventory of Child/Adolescent Individual Differences was employed as a measure of students’ personality traits at the end of elementary schooling (mean age = 14.7 years) and two years later when the participants attended secondary schools. The trait ratings were obtained through self‐, maternal and peer reports at both measurement occasions. They explained substantial portions of unique variance in the students’ GPA concurrently, and over time. Ratings by each of the three groups of informants had an incremental validity over one another in predicting school grades. Among personality variables, conscientiousness and low extraversion were consistently predictive of GPA.  相似文献   
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Research on categories and markets suggests that audiences rely on categorical distinctions to make sense of market offerings. Market offerings that deviate from category norms risk devaluation. Although literature in this area has led to valuable insights, scholars have begun to question whether there has been an overemphasis on conformity, leaving existing theories ill-equipped to account for innovation. Within this context, we argue that research on authenticity in cultural sociology offers a useful platform for theorizing. We draw on the work of Peterson (1997), who underscores the importance of signals in evaluation. Objective features of market offerings (e.g., quality) matter, but particularly for innovations, these features are not readily visible. Because authentic producers are typically thought to be more committed, capable, and intrinsically motivated, when visibility of such objective features is lacking, authenticity may serve as an alternative indicator of value. Appearing authentic requires signaling believability with respect to category norms, while also being distinctive. Using data on 684 firms from five high technology sectors, we explore the relationship between authenticity and investor perceptions of value. Focusing on three different proxies for signals of authenticity—networks, governance, and narratives—we find a curvilinear association between conformity/distinctiveness and Tobin's q. Consistent with our view of authenticity as a signal, we also find that this relationship flattens as firms gain better track records and face stiffer competition.  相似文献   
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