Can imagery training help children who have comprehension problems?

An experiment is reported that explored whether training in mental imagery would improve text comprehension in 9-year-old children. Two groups of children were compared: good and poor comprehenders. The groups were matched on a test of vocabulary and decoding, but differed on a comprehension test. The results showed that a three-session programme of training in imagery benefited the poor, but not the good, comprehenders, by comparison with a control group who merely answered questions about the same passages. The results are discussed in relation to possible causes of children's comprehension difficulties.     

Modeling Collaboration for Middle-Level Teacher Candidates Through Co-Teaching

The purpose of this analysis was to determine if the implementation of co-teaching was an effective instructional practice for graduate-level teacher candidates (hence forth referred to as candidates) in a Middle Childhood Education cohort. The goals were to determine (1) if co-teaching promoted candidate learning and (2) if co-teaching provided effective modeling for the candidates so they would be able to utilize it in their own future classrooms. Both quantitative and qualitative data were analyzed from course evaluations and pre- and post-surveys. Results indicated that candidates' educational experiences were enhanced as a result of the co-teaching experience, particularly with the use of team teaching, parallel teaching, and station teaching strategies. Additionally, evidence suggests that the use of co-teaching provided effective modeling for the candidates.     

The relationship between bowling action classification and three-dimensional lower trunk motion in fast bowlers in cricket

Abstract

Lower back injuries, specifically lumbar stress fractures, account for the most lost playing time in professional cricket. The aims of this study were to quantify the proportion of lower trunk motion used during the delivery stride of fast bowling and to examine the relationship between the current fast bowling action classification system and potentially injurious kinematics of the lower trunk. Three-dimensional kinematic data were collected from 50 male professional fast bowlers during a standing active range of motion trial and three fast bowling trials. A high percentage of the fast bowlers used a mixed bowling action attributable to having shoulder counter-rotation greater than 30°. The greatest proportion of lower trunk extension (26%), contralateral side-flexion (129%), and ipsilateral rotation (79%) was used during the front foot contact phase of the fast bowling delivery stride. There was no significant difference in the proportions of available lower trunk extension, contralateral side-flexion, and ipsilateral rotation range of motion used during fast bowling by mixed and non-mixed action bowlers. Motion of the lower trunk, particularly side-flexion, during front foot contact, in addition to variables previously known to be related to back injury (e.g. shoulder counter-rotation), should be examined in future cross-sectional and prospective studies examining the fast bowling action and low back injury.     

Active Learning and Student-centered Pedagogy Improve Student Attitudes and Performance in Introductory Biology

We describe the development and implementation of an instructional design that focused on bringing multiple forms of active learning and student-centered pedagogies to a one-semester, undergraduate introductory biology course for both majors and nonmajors. Our course redesign consisted of three major elements: 1) reordering the presentation of the course content in an attempt to teach specific content within the context of broad conceptual themes, 2) incorporating active and problem-based learning into every lecture, and 3) adopting strategies to create a more student-centered learning environment. Assessment of our instructional design consisted of a student survey and comparison of final exam performance across 3 years—1 year before our course redesign was implemented (2006) and during two successive years of implementation (2007 and 2008). The course restructuring led to significant improvement of self-reported student engagement and satisfaction and increased academic performance. We discuss the successes and ongoing challenges of our course restructuring and consider issues relevant to institutional change.     

Effect of vitamin C and E activity on surgically removed cataractous human lens epithelium cells

Oxidative stress has been proposed as a common underlying mechanism of cataractogenesis. Experimental and observational data suggest that micronutrients like vitamin C and vitamin E with antioxidant capabilities may retard the development of age-related cataract. Effect of these factors on lens epithelium cells, center of lens metabolic activities, is not completely elucidated. The aim of present study was to examine the effect of vitamin C and E on surgically removed lens epithelium cells of patients with cataract. Capsulorhexis samples were collected from 170 patients, admitted for cataract surgery. Catalase specific activity was estimated in lens epithelium cells with and without vitamin (C or E) treatment at different concentration for different time duration. Student’s t-test was employed for data analysis. We observed that in ex-vivo condition, a) both vitamin C and E bring about a decrease in catalase activity in lens epithelial cells. b) vitamin C showed toxic effect at high concentration. c) 100μM was the optimum concentration at which both vitamins showed maximum antioxidant activity. It was concluded that both vitamin C and E has direct effect on lens epithelium cells. At optimum concentration, they can reduce oxidative stress in these cells thus can support to prevent or delay cataract development.     

Differential pH sensitivity of tissue superoxide dismutases

Superoxide dismutase (SOD) activities in the human and rat RBCs and rat liver, kidney, brain and heart mitochondria as well as cytosolic fractions were determined by the pyrogallol assay procedure with slight modifications. Measurements were carried out in 0.1 M potassium phosphate buffer pH 8.0 and 9.2 to assess the pH stability of the SODs from various systems. Under these conditions the SODs from different systems including RBCs exhibited differential pH stability i.e. they displayed differential susceptibility at pH 9.2. Even in a given tissue, the mitochondrial and cytosolic SODs contents show a tissue-specific pattern. Our results also suggest that measurements carried out at pH 8.0 may give more realistic estimates of SOD activities.     

Monitoring and Root Cause Analysis of Clinical Biochemistry Turn Around Time at an Academic Hospital

Quality can be defined as the ability of a product or service to satisfy the needs and expectations of the customer. Laboratories are more focusing on technical and analytical quality for reliability and accuracy of test results. Patients and clinicians however are interested in rapid, reliable and efficient service from laboratory. Turn around time (TAT), the timeliness with which laboratory personnel deliver test results, is one of the most noticeable signs of laboratory service and is often used as a key performance indicator of laboratory performance. This study is aims to provide clue for laboratory TAT monitoring and root cause analysis. In a 2 year period a total of 75,499 specimens of outdoor patient department were monitor, of this a total of 4,142 specimens exceeded TAT. With consistent efforts to monitor, root cause analysis and corrective measures, we are able to decreased the specimens exceeding TAT from 7–8 to 3.7 %. Though it is difficult task to monitor TAT with the help of laboratory information system, real time documentation and authentic data retrievable, along with identification of causes for delays and its remedial measures, improve laboratory TAT and thus patient satisfaction.     

Serum Levels of Glycoproteins are Elevated in Patients with Ovarian Cancer

Identification of reliable biomarkers for detection and staging of cancer and monitoring the outcome of anticancer therapy has been considered to be of high importance. We aimed to estimate the levels of serum glycoproteins, protein bound-hexose, protein bound hexosamine, protein bound fucose, protein bound sialic acid and protein bound carbohydrate in 32 ovarian cancer patients and compared them with the levels that found in 25 normal subjects. As compared to the normal subjects, all the four fractions of glycoproteins level were significantly elevated in ovarian cancer patients (p < 0.05). Chemotherapy in these patients significantly decreased the levels of serum glycoproteins (p < 0.05). Thus, high levels of serum glycoproteins in ovarian cancer patients could be due to abnormal protein glycosylation indicating malignant transformation of the cells.     

Antinuclear Antibody Profiling in Patients of a Tertiary Care Centre in Central India

The incidence of autoimmune disorders that includes the connective tissue diseases has seen a rise in India in recent times. Antinuclear antibodies, the telltale sign of systemic autoimmune response, thus can be used as a screening tool and also to support the diagnosis of systemic autoimmune disease. The present retrospective cross- sectional analysis aimed to study the antinuclear antibodies profile (patterns and specific antibody reactivity) amongst suspected cases of auto-immune disorders at a tertiary care teaching hospital. The study retrieved and reviewed reports of 644 patients sent for ANA testing by indirect immunofluorescence assay over a period of 1 year by different specialty departments. Positive samples were further processed for anti-ds-DNA antibody and antibodies to extractable nuclear antigen. Data collected was statistically analysed. ANA pattern positivity was observed in 31% of cases and a positive antibody reactivity was seen in 66% of them. Female predominance (82%) was noted in both pattern positivity and antibody reactivity. High levels of pattern positivity and antibody reactivity was found in the young adults (45.9%). Amongst the ANA patterns, the nuclear homogenous pattern was found the commonest. The common antibodies associated with this pattern were anti-dsDNA and U1 Sm/RNP antibodies. A stronger fluorescence intensity on initial screening showed a higher confirmation rate for specific antibodies on immunoassay. High occurrence of positive ANA patterns in autoimmune disorders suggests its utilization as a screening tool for them and would also play an adjuvant to the diagnosis. Early knowledge about future autoimmunity will earn better prognostic achievements through better treatment interventions.