Single-cell yolk-shell nanoencapsulation for long-term viability with size-dependent permeability and molecular recognition

Like nanomaterials, bacteria have been unknowingly used for centuries. They hold significant economic potential for fuel and medicinal compound production. Their full exploitation, however, is impeded by low biological activity and stability in industrial reactors. Though cellular encapsulation addresses these limitations, cell survival is usually compromised due to shell-to-cell contacts and low permeability. Here, we report ordered packing of silica nanocolloids with organized, uniform and tunable nanoporosities for single cyanobacterium nanoencapsulation using protamine as an electrostatic template. A space between the capsule shell and the cell is created by controlled internalization of protamine, resulting in a highly ordered porous shell-void-cell structure formation. These unique yolk-shell nanostructures provide long-term cell viability with superior photosynthetic activities and resistance in harsh environments. In addition, engineering the colloidal packing allows tunable shell-pore diameter for size-dependent permeability and introduction of new functionalities for specific molecular recognition. Our strategy could significantly enhance the activity and stability of cyanobacteria for various nanobiotechnological applications.     

Student-staff partnerships in academic development: the course design studio as a model for sustainable course-wide impact

ABSTRACT

Sector-wide research has shown the benefits of student-staff partnerships in course design whilst highlighting the complexity of this work, and the difficulties in gaining traction to create sustained ways of working. Reflections by academic developers on the roles and partnerships in course design at one Australian university reveal the critical three-way partnership among academic developers, students, and academics. The benefits brought by a Course Design Studio model in providing a liminal space to sustain positive three-way collaborations are outlined. This paper offers a conceptual argument that addresses areas of concern often encountered in traditional course design student-staff partnership relationships.     

Comparing problem-based learning students to students in a lecture-based curriculum: learning strategies and the relation with self-study time

In educational theory, deep processing (i.e., connecting different study topics together) and self-regulation (i.e., taking control over one’s own learning process) are considered effective learning strategies. These learning strategies can be influenced by the learning environment. Problem-based learning (PBL), a student-centered educational method, is believed to stimulate the use of these effective learning strategies. Several aspects of PBL such as discussions of real-life problems, selecting literature by the students themselves, and formulating answers to learning issues encourage students’ use of deep processing and self-regulation. In the present study, third-year PBL law students were compared to third-year law students of a lecture-based program with respect to their learning strategies, which were measured with the Inventory Learning Styles (ILS; Vermunt in British Journal of Educational Psychology, 68, 149–171, 1998). In addition, the relation between time invested in self-study and learning strategies, when taking the instructional method into account, was explored. Results showed that PBL students reported to apply deep processing, self-regulation, and external regulation more frequently than their non-PBL counterparts. PBL seems to contribute to the use of effective learning strategies, but PBL students also relied more often on external sources for their regulation, such as teachers, course material, and assessment.     

Simulations for the Assessment of Counselling Skills

Assessment of students’ communication skills after a course in counselling, in which the students are prepared for work practice, requires another assessment method than the traditional written examination. In this paper we describe the construction and evaluation of simulations. The results of an investigation into the quality of the simulations show that they enable objective assessment of students’ mastery of skills in the situation which is simulated. In order to achieve generalisable scores, i.e. scores which indicate how well a student will perform in counselling interviews in general, more than one simulation has to be administered. Although the simulation is not an efficient instrument, its benefits are high: weaknesses in students’ performances will be detected so that remedial teaching can be offered, and clinical practice can be preserved for counsellors with a less than sufficient ability in counselling skills     

Differences in game reading between selected and non-selected youth soccer players

Applying an established theory of cognitive development―Skill Theory―the current study compares the game-reading skills of youth players selected for a soccer school of a professional soccer club (n = 49) and their non-selected peers (n = 38). Participants described the actions taking place in videos of soccer game plays, and their verbalisations were coded using Skill Theory. Compared to the non-selected players, the selected players generally demonstrated higher levels of complexity in their game-reading, and structured the information of game elements―primarily the player, teammate and field―at higher complexity levels. These results demonstrate how Skill Theory can be used to assess, and distinguish game-reading of youth players with different expertise, a skill important for soccer, but also for other sports.     

‘The bond with reality is cut’ — Freudenthal on the foundations of geometry around 1900

In the late 1950's Freudenthal published several articles on the history of geometry around 1900, in particular on Hilbert's innovative approach to the foundations of geometry. Especially his essay-review of the eighth edition of Hilbert'sGrundlagen der Geometrie has become a standard reference in historical studies of geometry. In the present article I discuss Freudenthal's contribution to our understanding of the development of geometry at the turn of the century and his style in historical research.     

How to assess for improvement of learning

This review summarizes and builds on a seminar about assessment of student learning in higher education. Assessment can be looked upon as simply something that has to be done at the end of a course. During the course of discussions at the seminar the participants became more aware of how assessment can have an impact on learning. This means that assessment can be used as a means to improve learning. This realization is not a new one, but it is highlighted here in a more coherent and concise way than usual. Many alternative methods of assessment are possible. Some instructional design rules will be presented here for designing assessment sessions in such a way that learning can be improved. When designing an assessment method, one can be guided by the following considerations. The content of assessment should be chosen in accordance with the learning outcomes one hopes to achieve. The organization of assessment can be designed in such a way that the desired learning process is promoted. The outcome of assessment can provide feedback to many of the stakeholders: to the students on their learning process; to the faculty on its outcomes; and to the teacher by pointing out the following steps to be taken in improving assessment, learning and teaching.