论隐性知识及其在技术创新中的作用

在分析、界定隐性知识概念及其重要特征的基础,认为隐性知识在企业技术创新中具有特别重要的意义,它对企业长期的进步和实业的成功具有不可忽视的重要作用。使用、分享和汲取技术创新人员的隐性知识,把他们的创造力真正转变为发明创造,将成为现代企业技术创新的一种内在动力。     

对地方自然科学基金绩效评估的若干问题探讨

绩效评估是地方自然科学基金管理工作的一项重要内容,是提高基金科学管理水平的必然要求。本文结合浙江省自然科学基金委员会的管理实践,对地方自然科学基金取得的阶段性成果进行绩效评估的意义、内容、评估方法和应遵循的原则以及其它若干问题进行了探讨。绩效评估工作的有效开展,对于提高基金的管理水平和使用效率是一个有益的尝试。     

Sequence- and structure-selective mRNA m5C methylation by NSUN6 in animals

mRNA m⁵C, which has recently been implicated in the regulation of mRNA mobility, metabolism and translation, plays important regulatory roles in various biological events. Two types of m⁵C sites are found in mRNAs. Type I m⁵C sites, which contain a downstream G-rich triplet motif and are computationally predicted to be located at the 5^′ end of putative hairpin structures, are methylated by NSUN2. Type II m⁵C sites contain a downstream UCCA motif and are computationally predicted to be located in the loops of putative hairpin structures. However, their biogenesis remains unknown. Here we identified NSUN6, a methyltransferase that is known to methylate C72 of tRNA^Thr and tRNA^Cys, as an mRNA methyltransferase that targets Type II m⁵C sites. Combining the RNA secondary structure prediction, miCLIP, and results from a high-throughput mutagenesis analysis, we determined the RNA sequence and structural features governing the specificity of NSUN6-mediated mRNA methylation. Integrating these features into an NSUN6-RNA structural model, we identified an NSUN6 variant that largely loses tRNA methylation but retains mRNA methylation ability. Finally, we revealed a weak negative correlation between m⁵C methylation and translation efficiency. Our findings uncover that mRNA m⁵C is tightly controlled by an elaborate two-enzyme system, and the protein-RNA structure analysis strategy established may be applied to other RNA modification writers to distinguish the functions of different RNA substrates of a writer protein.     

ENSO and Southeast Asian biomass burning modulate subtropical trans-Pacific ozone transport

Trans-Pacific transport of enhanced ozone plumes has been mainly attributed to fossil fuel combustion in Asia in spring, but less attention has been paid to vegetation fires in Asia. Here we show that the El Niño-Southern Oscillation (ENSO)-modulated fires in Southeast Asia, rather than Asian fossil fuel plumes, dominate the interannual variability of springtime trans-Pacific transport of ozone across the entire North Pacific Ocean. During El Niño springs, the intensified fires from both the Indochinese Peninsula and Indonesia, together with large-scale circulation anomalies, result in enhanced ozone plumes that stretch over 15 000 km in both the lower-middle and upper troposphere. This enhancement is also observed in the in situ measurements of ozone concentration, with an almost 10% increase at Mauna Loa Observatory, Hawaii, a unique site to monitor the long-distance transport over the North Pacific. This study reports an unexpectedly strong influence of vegetation fires, linked with climate variability, on global tropospheric chemistry and proves once more how complex the interactions in the climate system are.     

高职特色校园文化建设途径探析

本文针对高职院校特色校园文化建设存在的问题及原因进行了分析阐述,在此基础上,从建设思路的构建、专业教学体系、校企文化融合、校行文化对接等方面提出了一些构建高职特色校园文化的有效途径。     

跨文化语言教学法(英文)

跨文化语言教学法是第二语言教学中的出现的一个新方法。其强调了文化因素在二语教学中的效用。本文立足于多角度类比语言、文化之定义,从跨文化语言教学法的基本元素入手,对这个二语教学的新方法进行了概要的介绍。     

复述策略在生物学教学中的运用

1复述策略及其心理学基础复述策略是指为了在记忆中保持重要信息而对信息进行重复识记的策略。德国著名的心理学家艾宾浩斯首先对遗忘现象做了系统的研究,并经过归纳和总结绘制出艾宾浩斯     

我国中职教师专业发展研究热点及趋势探析

本文系统梳理了我国中职学校教师专业发展研究的脉络,以中国知网数据库中的期刊论文为研究对象,运用Citespace可视化工具,对作者与机构分布、关键词共现及聚类情况进行分析,阐述了我国中职学校教师专业发展研究的基本情况,以期为今后相关研究提供参考。     

A quantitative and model-driven approach to assessing higher education in the United States of America

University ranking or higher education assessment in general has been attracting more and more public attention over the years. However, the subjectivity-based evaluation index and indicator selections and weights that are widely adopted in most existing ranking systems have been called into question. In other words, the objectivity and impartiality of those rankings has been worrisome. To address these concerns, this paper presents a quantitative and model-driven approach to acquiring the evaluation index and indicator weights in the US News & World Report ranking system. Structural equation modelling will be applied to mine non-subjective weights from collected data. The proposed approach will be validated using two groups of United States universities, National Universities and Liberal Arts Colleges, classified by the US News & World Report. Managerial and administrative implications will also be explored. This study shows a very promising future because it opens a new venue for the scholars and practitioners in the higher education assessment field to develop a real-time, scalable and model-driven higher education ranking system.     

论高校工程管理专业人才教学创新的研究与对策

通过对高校工程管理专业人才教学的现状及存在的问题,对目前高校工程管理专业的教学进行研究分析,并对该专业提出几点建议与对策。