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161.
Sweat lactate reflects eccrine gland metabolism. However, the metabolic tendencies of eccrine glands in a hot versus thermoneutral environment are not well understood. Sixteen male volunteers completed a maximal cycling trial and two 60-min cycling trials [30°C?=?30±1°C and 18°C?=?18±1°C wet bulb globe temperature (WBGT)]. The participants were requested to maintain a cadence of 60 rev?·?min?1 with the intensity individualized at ~ 90% of the ventilatory threshold. Sweat samples at 10, 20, 30, 40, 50 and 60?min were analysed for lactate concentration. Sweat rate at 30°C (1380±325?ml?·?h?1) was significantly greater (P<0.05) than at 18°C (632±311?ml?·?h?1). Sweat lactate concentration was significantly greater (P<0.05) at each time point during the 18°C trial, with values between trials tending to converge across time. During the 30°C trial, both heart rate (20, 30, 40, 50 and 60?min) and rectal temperature (30, 40, 50 and 60?min) were significantly higher than in the 18°C trial. Higher sweat lactate concentrations coupled with lower sweat rates may indicate a greater relative contribution of oxygen-independent metabolism within eccrine glands during exercise at 18°C. Decreases in sweat lactate concentration across time suggest either greater dilution due to greater sweat volume or increased reliance on aerobic metabolism within eccrine glands. The convergence of lactate concentrations between trials may indicate that time-dependent modifications in sweat gland metabolism occur at different rates contingent partially on environmental conditions. 相似文献
162.
Mohd Azhar Abdul Razak Kai F. Hoettges Henry O. Fatoyinbo Fatima H. Labeed Michael P. Hughes 《Biomicrofluidics》2013,7(6)
Whilst laboratory-on-chip cell separation systems using dielectrophoresis are increasingly reported in the literature, many systems are afflicted by factors which impede “real world” performance, chief among these being cell loss (in dead spaces, attached to glass and tubing surfaces, or sedimentation from flow), and designs with large channel height-to-width ratios (large channel widths, small channel heights) that make the systems difficult to interface with other microfluidic systems. In this paper, we present a scalable structure based on 3D wells with approximately unity height-to-width ratios (based on tubes with electrodes on the sides), which is capable of enriching yeast cell populations whilst ensuring that up to 94.3% of cells processed through the device can be collected in tubes beyond the output. 相似文献
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This article examines the experience of 24 BSW students in a faculty-mentored undergraduate research experience (URE) over the course of 1 academic year. In particular, we sought to better understand students’ self-perceived sense of competency across 15 specific research skills. In addition, we examined the URE’s impact on students’ knowledge about and attitudes toward research, as well as anxiety levels about research. A cross-sectional pre- and posttest design utilized both quantitative (survey) and qualitative (focus group) methodologies. All of the students’ ratings of their 15 research skills improved over time; 3 were statistically significant. Students demonstrated the most gain in evidence-based practice, ability to use statistical software, and data entry and analysis. Both knowledge about and attitude toward research improved significantly. Anxiety levels were surprisingly low. The importance of faculty mentoring is discussed, and suggestions for future research are provided. 相似文献
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167.
The shift from a centralized to a decentralized school system can be seen as a solution to an uncertain problem. Through analysing the displacements in the concept of equivalence within Sweden’s decentralized school system, this study illustrates how the meaning of the concept of equivalence shifts over time, from a more collective target achievement for the educational system as a whole to a more individually interpreted goal‐fulfilment. 相似文献
168.
This paper reports findings from a study that focused on the experiences of research-intensive academics in relation to the Excellence in Research for Australia (ERA) Framework. Interviews with academic staff at different career stages and across all academic faculties followed completion of a short survey in which respondents compared their publishing behaviour before and since implementation of the new Framework. Respondents were highly conscious that ERA had prompted a shift in publishing behaviour to meet often competing demands of individual research interests, institution, discipline and the international research community. Indeed, the study revealed academics to be positioned in contradictory ways in relation to their research and publishing, heightened by the instability of the Framework's assessment mechanisms. The experience of researchers up to, and including, the decision to abandon journal ranking provides valuable insights into the precarious and reactionary nature of academic research careers and the ability of both individuals and institutions to negotiate the rapid rate of change. These insights include tension between personal research priorities and ERA requirements, particularly in relation to writing for the most relevant audience, and concerns about the right to exercise academic freedom. 相似文献
169.
Richard C. Hughes D. D. 《Religious education (Chicago, Ill.)》2013,108(4):392-397
Katharine Drexel was an important educator who taught profound lessons to the Roman Catholic Church and American society about the responsibility of privilege and the irresponsibility of prejudice. As a professed nun dedicated to the education of Black and Native Americans, she taught both intentionally and by example. Religious educators, seeking to educate for peace and justice, often point to Katharine's life work as an example of the application of Catholic social teaching. This article argues that Katharine's educational import in regards to Catholic social teaching goes much deeper than the concrete examples of her life's work. By studying Katharine's life, religious educators can illustrate the foundational attitudes and habits necessary for the principle of social justice to take root. This will be articulated in terms of underlying emphases found in aspects of Katharine's story: emphasis on totality, on clarity of vision and purpose, on evangelization, on family ethical formation, on moral education, and on Eucharistic spirituality. A corresponding action for religious educators will be suggested. 相似文献
170.