爸爸妈妈 你们为什么不吻我呢

小女孩辛迪和她的爸爸妈妈生活在一起。她的家庭并不富裕,但一家人非常和睦,生活也很幸福。然而生活中好像还存在着什么缺憾,辛迪没意识到。辛迪9岁那年,第一次在外面过夜,那是在她的好朋友黛比家。睡觉前黛比的妈妈进来,分别轻轻地吻了吻她们的额头,并向她们道了“晚安”。“我爱你,黛比。”当黛比的妈妈吻过黛比之后,轻声地说道。“我也爱您,妈妈。”黛比喃喃地应道。面对此情此景,辛迪不禁大吃一惊,心中久久不能平静。从她记事以来,从来就没有人吻过她,还向她道晚安、说爱她之类的话。整整一夜,她的眼前始终闪现着黛比的妈妈轻吻黛比时的…     

FLOSSWorld全球调查结果显示服务器更多使用开源软件

FLOSSWorld调查的主体由5部分构成,包括:个人(Private sector)、政府(Government sector)、开源社区参与者(Open Source participants community)、高校管理者(Heigher Education Institutes——Administrators)、高校信息部门主管(Heigher Education Institute——ITManagers)     

Synthetic and biological studies on a cyclopolypeptide of plant origin

Objective: A natural cyclic peptide previously isolated from Citrus medica was synthesized by coupling oftetrapep-tide units Boc-Leu-Pro-Trp-Leu-Ome and Boc-Ile-Ala-Ala-Gly-Ome after proper deprotection at carboxyl and amino terminals followed by cyclization of linear octapeptide segment.Methods: Solution phase technique was adopted for the synthesis of cyclooctapeptide--sarcodactylamide.Required tetrapeptide units were prepared by coupling of Boc-protected dipeptides viz.Boc-Leu-Pro-OH and Boc-Ile-Ala-OH with respective dipeptide methyl esters Trp-Leu-Ome and Ala-Gly-Ome.Cyclization of linear octapeptide unit was done by p-nitrophenyl ester method.The structure of synthesized cyclopolypeptide was elucidated by FTIR,1H NMR,13C NMR,FABMS spectral data and elemental analysis.The newly synthesized peptide was evaluated for dif-ferent pharmacological activities including antimicrobial,anthelmintic and cytotoxic activities.Results: Synthesis of sarcodac-tylamide was accomplished with >78% yield utilizing dicyclohexylcarbodiimide (DCC) as coupling agent.Newly synthesized peptide possessed potent cytotoxic activity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines,in addition to moderate anthelmintic activity against earthworms Megascoplex konkanensis,Pontoscotex corethruses and Eudrilus sp.Moreover,cyclopolypeptide displayed good antimicrobial activity against pathogenic fungi Candida albicans and Gram-negative bacteria Pseudomonas aeruginosa,in comparison to standard drugs griseofulvin and ciprofloxacin.Conclusion: Solution phase technique employing DCC and triethylamine (TEA) as base proved to be effective for the synthesis of natural cyclooctapeptide.N-methyl morpholine (NMM) was found to be a better base for the cyclization of linear octapeptide unit in comparison to TEA and pyridine.     

Developmental links of very early phonological and language skills to second grade reading outcomes: strong to accuracy but only minor to fluency

The authors examined second grade reading accuracy and fluency and their associations via letter knowledge to phonological and language predictors assessed at 3.5, 4.5, and 5.5 years in children in the Jyv?skyl? Longitudinal Study of Dyslexia. Structural equation modeling showed that a developmentally highly stable factor (early phonological and language processing [EPLP]) behind key dyslexia predictors (i.e., phonological awareness, short-term memory, rapid naming, vocabulary, and pseudoword repetition) could already be identified at 3.5 years. EPLP was significantly associated with reading and spelling accuracy and by age with letter knowledge. However, EPLP had only a minor link with reading fluency, which was additionally explained by early letter knowledge. The results show that reading accuracy is well predicted by early phonological and language skills. Variation in fluent reading skills is not well explained by early skills, suggesting factors other than phonological core skills. Future research is suggested to explore the factors behind the development of fast and accurate decoding skills.     

父亲的白兰花

屡屡的失败让我疲惫不堪,心里的石头越来越重。可是凭着一种坚定的信念,我又一次加入了考试大军。今年8月25日是我第三次参加托福考试。24日深夜,狂风大作,暴雨如瀑,使本来就没有睡意的我更加心烦意乱。起身下床,发现厨房灯亮着,老爸背朝着我,正在专注地做着     

基于国家教育标准的地理教材

为进一步增强美国地理教育。我们要做的许多事情之一就是改进教材的质量。其中最主要的三个方面的任务是:(1)开发优良的教材,(2)利用教师联盟的在职培训网络和职前教育计划培训教师使用这种新教材,(3)通过提供强有力的课程指导,特别是将教材与师资培训和基于国家     

让学生在自主选择中健康成长

历时几千年的教育最终演变成了一个复杂系统，而光怪陆离的复杂系统，很容易使人们忘记教育的本真目标。当我们被知识、价值、技能、态度等教育的具体目标以及他们之间的关系弄得一头雾水时，可能缺失的恰恰是对教育最初本真目标的准确把握。     

关于马克思列宁主义基础的備课工作

伏龍芝軍事學院馬克思列寧主義敎研室認为講課在馬克思列寧主義科学的敎學中有特别重要的意义,因此它進行工作的方針首先是改进講課的質量:按照新的教學大綱的要求提高講課的思想理论水平,改善備課和講課的方法。敎研室認为作好備課工作的首要條件,是根據原著——黨代麦大會、代表會議和蘇共中央全會的决議並根據‘聯共(布)黨史簡明敎程’和馬克思列寧主义經典著作中的思想來編寫講義。大家知道,直到最近为止,各大學对於在讲课之中阐述和宣傳黨代表大會、代表會議和蘇共中央全会等會議的决議這一點是注意不够的。這一個嚴重的缺點,過去是由馬克思列寧主義基礎這門課程的敎学大綱本身引起的。新的敎學大綱要求所有敎員堅决消除這个缺點。     

Deafness, language skills, and rehearsal: a model for the development of a memory strategy

We review a series of studies that evaluate the role of developing language skills as a prerequisite to spontaneous rehearsal use in deaf populations. We propose a theoretical model that summarizes the contribution of language skills by highlighting the interrelations among age, language proficiency, and automatized language skills. In an initial test of the model, an index of deaf children's language experience was found to be an almost complete mediator of strategy use. Increasing language proficiency, therefore, was implicated as a critical variable in predicting children's spontaneous rehearsal use, minimizing any direct contribution from age per se. In a more direct assessment of the link between general language proficiency and rehearsal use, pragmatic language skills (as measured by the Language Proficiency Profile: LPP-I) were found to be a nearly complete mediator of rehearsal use, with the remaining contributions of age and language experience being nonsignificant. Language proficiency, therefore, was identified as a strong and necessary prerequisite for rehearsal to be used spontaneously as a memory strategy. The additional hypothesis that the automatization of these general language skills, measured by a rapid automatized naming task (RAN), contributes to spontaneous rehearsal was also evaluated. Automatized language emerged as a partial mediator of the language proficiency → rehearsal use relation but additional language-processing variables were implicated. We discuss these findings as they relate to issues around the nature of language proficiency and the identification of those automatized language skills involved in rehearsal.