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151.
Ina Drejer 《Research Policy》2004,33(3):551-562
In order to compensate for decades of neglect of services in innovation studies, a strand of literature has emerged, which emphasises alleged distinctive features of service innovation. These studies apply innovation concepts developed especially for services, thereby contributing to the existing divide between manufacturing and services. The present paper demonstrates that Schumpeter’s original innovation concept is indeed broad enough to encompass services and manufacturing, and that a more direct reference to Schumpeter, in particular innovation as a contrast to activities based on routine systems, in service oriented studies would add a needed theoretical and conceptual strengthening to service innovation studies. 相似文献
152.
Yang Xinrong Schwarz Björn Leung Issic K. C. 《Educational Studies in Mathematics》2022,109(2):409-429
Educational Studies in Mathematics - Although mathematical modeling plays an important role in many curricula worldwide, significant discrepancies persist in the importance of mathematical modeling... 相似文献
153.
Baumler DJ Banta LM Hung KF Schwarz JA Cabot EL Glasner JD Perna NT 《CBE life sciences education》2012,11(1):81-93
Genomics and bioinformatics are topics of increasing interest in undergraduate biological science curricula. Many existing exercises focus on gene annotation and analysis of a single genome. In this paper, we present two educational modules designed to enable students to learn and apply fundamental concepts in comparative genomics using examples related to bacterial pathogenesis. Students first examine alignments of genomes of Escherichia coli O157:H7 strains isolated from three food-poisoning outbreaks using the multiple-genome alignment tool Mauve. Students investigate conservation of virulence factors using the Mauve viewer and by browsing annotations available at the A Systematic Annotation Package for Community Analysis of Genomes database. In the second module, students use an alignment of five Yersinia pestis genomes to analyze single-nucleotide polymorphisms of three genes to classify strains into biovar groups. Students are then given sequences of bacterial DNA amplified from the teeth of corpses from the first and second pandemics of the bubonic plague and asked to classify these new samples. Learning-assessment results reveal student improvement in self-efficacy and content knowledge, as well as students' ability to use BLAST to identify genomic islands and conduct analyses of virulence factors from E. coli O157:H7 or Y. pestis. Each of these educational modules offers educators new ready-to-implement resources for integrating comparative genomic topics into their curricula. 相似文献