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This article takes a close analytical look at the internationalization of higher education, asking penetrating questions with regard to its basis, its forms, and its results. The author is particularly concerned with problems of asymmetry with regard to the educational links, particularly at higher education level, between the developed western democracies and the developing countries. Going beyond the question of brain drain, the article probes the problem of the alienation of third world academics trained in the higher education institutions of developed countries. While on the balance the author praises the results of the internationalization of higher education and, at any rate, recognizes that it is here to stay, he cautions all those involved in it be aware of who in fact gains and who loses as a result of it.  相似文献   
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Probabilistic topic models are unsupervised generative models which model document content as a two-step generation process, that is, documents are observed as mixtures of latent concepts or topics, while topics are probability distributions over vocabulary words. Recently, a significant research effort has been invested into transferring the probabilistic topic modeling concept from monolingual to multilingual settings. Novel topic models have been designed to work with parallel and comparable texts. We define multilingual probabilistic topic modeling (MuPTM) and present the first full overview of the current research, methodology, advantages and limitations in MuPTM. As a representative example, we choose a natural extension of the omnipresent LDA model to multilingual settings called bilingual LDA (BiLDA). We provide a thorough overview of this representative multilingual model from its high-level modeling assumptions down to its mathematical foundations. We demonstrate how to use the data representation by means of output sets of (i) per-topic word distributions and (ii) per-document topic distributions coming from a multilingual probabilistic topic model in various real-life cross-lingual tasks involving different languages, without any external language pair dependent translation resource: (1) cross-lingual event-centered news clustering, (2) cross-lingual document classification, (3) cross-lingual semantic similarity, and (4) cross-lingual information retrieval. We also briefly review several other applications present in the relevant literature, and introduce and illustrate two related modeling concepts: topic smoothing and topic pruning. In summary, this article encompasses the current research in multilingual probabilistic topic modeling. By presenting a series of potential applications, we reveal the importance of the language-independent and language pair independent data representations by means of MuPTM. We provide clear directions for future research in the field by providing a systematic overview of how to link and transfer aspect knowledge across corpora written in different languages via the shared space of latent cross-lingual topics, that is, how to effectively employ learned per-topic word distributions and per-document topic distributions of any multilingual probabilistic topic model in various cross-lingual applications.  相似文献   
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We present a user-centred, task-oriented, comparative evaluation of two within-document retrieval tools. ProfileSkim computes a relevance profile for a document with respect to a query, and presents the profile as an interactive bar graph. FindSkim provides similar functionality to the web browser “Find” command. A novel simulated work task was devised, where participants are asked to identify (index) relevant pages of an electronic book, given topics from the existing book index. The original book index provides the ground truth, against which the indexing results of the participants can be compared. We confirmed a major hypothesis, namely ProfileSkim proved significantly more efficient than Find-Skim, as measured by time for task. The study indicates that ProfileSkim was as least as effective as FindSkim in identifying relevant pages, as measured by traditional information retrieval measures, and there is some evidence that ProfileSkim is a precision-enhancing tool. Based on qualitative data from questionnaires, we also provide strong evidence to support our conjecture that the participants would be more satisfied when using ProfileSkim than FindSkim. The experimental study confirmed the potential of relevance profiling for improving within-document retrieval. Relevance profiling should prove highly beneficial for users trying to identify relevant information within long documents.  相似文献   
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This study used focus groups to assess the feasibility and acceptability of adapting an Embodied Conversational Agent (ECA) to support decision-making about mode of birth after previous cesarean. Twelve women with previous cesareans, and eight prenatal providers at an academic, tertiary-care medical center, viewed a prototype ECA and were asked to share feedback on the potential role in helping women prepare for decision-making. Both groups felt that although it was somewhat “robot-like,” the ECA could provide easy access to information for patients and could augment the visit with providers. Future work is needed to improve ECA visual appeal and clarify the role and timing for utilization of decision aids using ECA technology to enhance the shared decision-making process.  相似文献   
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The rigidity of teachers unions has been given as a primary reason for their lack of representation among America’s rapidly growing, although still relatively small, charter school sector. In the case of post-Hurricane Katrina New Orleans, the city rapidly converted from a union-backed teacher workforce to a largely nonunionized charter school workforce in the years following state takeover and charter conversion. This makes the recent emergence of two single-school unions in charter schools there worthy of study. As the teachers attempt to organize single-school unions in a nearly all charter school system, what are their motivations? This case study of one of New Orleans’ emerging charter school unions found that pay inequities, job insecurity, a lack of teacher voice in school-level decisions, and a culture of compliance, all motivated teachers to seek unionization. Teachers hoped to promote equity and teacher involvement with their union, but the organizing effort did strain some relationships, particularly those involving middle management.  相似文献   
59.
Degas-driven flow is a novel phenomenon used to propel fluids in poly(dimethylsiloxane) (PDMS)-based microfluidic devices without requiring any external power. This method takes advantage of the inherently high porosity and air solubility of PDMS by removing air molecules from the bulk PDMS before initiating the flow. The dynamics of degas-driven flow are dependent on the channel and device geometries and are highly sensitive to temporal parameters. These dependencies have not been fully characterized, hindering broad use of degas-driven flow as a microfluidic pumping mechanism. Here, we characterize, for the first time, the effect of various parameters on the dynamics of degas-driven flow, including channel geometry, PDMS thickness, PDMS exposure area, vacuum degassing time, and idle time at atmospheric pressure before loading. We investigate the effect of these parameters on flow velocity as well as channel fill time for the degas-driven flow process. Using our devices, we achieved reproducible flow with a standard deviation of less than 8% for flow velocity, as well as maximum flow rates of up to 3 nL∕s and mean flow rates of approximately 1-1.5 nL∕s. Parameters such as channel surface area and PDMS chip exposure area were found to have negligible impact on degas-driven flow dynamics, whereas channel cross-sectional area, degas time, PDMS thickness, and idle time were found to have a larger impact. In addition, we develop a physical model that can predict mean flow velocities within 6% of experimental values and can be used as a tool for future design of PDMS-based microfluidic devices that utilize degas-driven flow.  相似文献   
60.

Background

Early diagnosis is crucial for management of patients with suspected acute myocardial infarction (AMI). Among innovative and promising biomarkers, the recent interest raised on glycogen phosphorylase isoenzyme BB (GPBB) has prompted us to perform a meta-analysis of published studies.

Materials and methods:

A systematic electronic search was carried out on PubMed, Web of Science and Google Scholar, with no date restriction, to retrieve all articles that have investigated the early diagnostic performance of GPBB in patients with suspected AMI, and directly reported or allowed calculation of sensitivity and specificity. A meta-analysis of the reported sensitivity and specificity of each study and pooled area under the curve (AUC) was then performed by random effect approach. Heterogeneity was assessed by I-square statistics.

Results:

Eight studies were finally selected for analysis (941 subjects; 506 cases and 435 controls), with a high heterogeneity (I-squared, 86.3%). The resulting pooled estimates and 95% confidence interval were 0.854 (0.801–0.891) for sensitivity, 0.767 (0.713–0.815) for specificity, 0.826 (0.774–0.870) for negative predictive value, 0.802 (0.754–0.844) for positive predictive value, and 0.754 (0.602–0.907) for AUC. In those studies that have simultaneously assessed GPBB and a troponin immunoassay, the combination of these biomarkers did not significantly improve the performance of troponin alone.

Conclusion:

GPBB does not meet the current requirements for an efficient diagnosis of AMI when used as a stand-alone test, whereas its combination with troponin merits further investigation in larger trials.  相似文献   
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