Some Aspects of the Development of the All-Russian Institute for Scientific and Technical Information

Although the USSR and the United States had a comparable number of employees in the field of scientific information, there was a substantial difference in funding, which resulted in a lack of information support for Soviet scientists. While 90% of the publications in the United States were available almost immediately after their release, in the USSR they were delayed by 1.5 to 2 years. Since the publication of the Abstracts Journal by VINITI (AJ), its content was consistently expanding and reached its peak in 1990 (1.5 million documents per year). The next quarter of a century was characterized by a decline in both the composition of the AJ and the time required for its document coverage. The steps for restructuring VINITI activities are discussed. The focus is made on improving the limited coverage of the Russian-language part of the global flow of scientific information by Western information systems.     

Scientometric Instruments of Research Funding

The issues related to funding of public research organizations are explored. The history of scientometric information systems is outlined. The advantages and disadvantages of a bibliometric approach to financing of research organizations are analyzed. The link between the assessment of the scientific and technological potential of an institution and the optimal allocation of funds is investigated. Recommendations on how to improve the efficiency of public resources allocated for scientific research are presented.     

An Analytical Review of Global Ecoinformatics Problems

Modern global eco-dynamics problems are discussed. It is noted that global changes are mostly characterized by several key features, such as their multicomponent nature, as well as interactivity and nonlinearity. These features challenge various forecast estimates in such a way that the concept of forecasting has been replaced over the last few years by a much more ambiguous concept of scenarios. The vagueness of scenarios is due to the problem of global climate change. A global climate–nature–society system model is outlined.     

Russian Science Citation Index: Areas for Development Identified by Active Users

The current state of the Russian Science Citation Index is analyzed. Several areas for its further development identified by long-standing active users, such as data searching, refinement, and storage; current user alerts; data input with the Science Index license; patent information; and the application programming interface (API) are investigated.     

The Role of Consistency in Detecting Deception: The Superiority of Correspondence over Coherence

Inconsistency is often considered an indication of deceit. The conceptualization of consistency used in deception research, however, has not made a clear distinction between two concepts long differentiated by philosophers: coherence and correspondence. The existing literature suggests that coherence is not generally useful for deception detection. Correspondence, however, appears to be quite useful. The present research developed a model of how correspondence is utilized to make judgments, and this article reports on four studies designed to elaborate on the model. The results suggest that judges attend strongly to correspondence and that they do so in an additive fashion. As noncorrespondent information accumulates, an increasingly smaller proportion of judges make truthful assessments of guilty suspects. This work provides a basic framework for examining how information is utilized to make deception judgments and forms the correspondence and coherence module of truth-default theory.     

Spanish historic archives’ use of websites as a management transparency vehicle

Against the backdrop of Spain’s Transparency Act, this article discusses the presence or otherwise of a series of document types, proposed as management-related transparency indicators, on 61 (8 national and 53 provincial) historic archive websites. Although examples of good practice were identified, the information provided was found to be scant, in particular as regards lines of action, organisational objectives and yearly reports. The information most commonly provided on the websites included the collection classification chart, service use regulations and citizen charters. The inference drawn was that archives, so intently focused on their role in the application of the Act by the organisations they serve, neglect their own administrative obligations in respect of its provisions. The recommendation is that as government-funded and subsidised public service institutions, historic archives should exercise transparency by furnishing the information stipulated in the Act on their websites.     

Effects of purposeful soccer heading on circulating small extracellular vesicle concentration and cargo

BackgroundConsidering the potential cumulative effects of repetitive head impact (HI) exposure, we need sensitive biomarkers to track short- and long-term effects. Circulating small extracellular vesicles (sEVs) (<200 nm) traffic biological molecules throughout the body and may have diagnostic value as biomarkers for disease. The purpose of this study was to identify the microRNA (miRNA) profile in circulating sEVs derived from human plasma following repetitive HI exposure.MethodsHealthy adult (aged 18–35 years) soccer players were randomly assigned to one of 3 groups: the HI group performed 10 standing headers, the leg impact group performed 10 soccer ball trapping maneuvers over 10 min, and the control group did not participate in any soccer drills. Plasma was collected before testing and 24 h afterward, and sEVs were isolated and characterized via nanoparticle tracking analysis. Next-generation sequencing was utilized to identify candidate miRNAs isolated from sEVs, and candidate microRNAs were analyzed via quantitative polymerase chain reaction. In silico target prediction was performed using TargetScan (Version 7.0; targetscan.org) and miRWalk (http://mirwalk.umm.uni-heidelberg.de/) programs, and target validation was performed using luciferase reporter vectors with a miR-7844-5p mimic in human embryonic kidney (HEK) 293T/17 cells.ResultsPlasma sEV concentration and size were not affected across time and group following repetitive HI exposure. After 24 h, the HI read count from next-generation sequencing showed a 4-fold or greater increase in miR-92b-5p, miR-423-5p, and miR-24-3p and a 3-fold or greater decrease in miR-7844-5p, miR-144-5p, miR-221-5p, and miR-22-3p. Analysis of quantitative polymerase chain reaction revealed that leg impact did not alter the candidate miRNA levels. To our knowledge, miR-7844-5p is a previously unknown miRNA. We identified 8 miR-7844-5p mRNA targets: protein phosphatase 1 regulatory inhibitor subunit 1B (PPP1R1B), LIM and senescent cell antigen-like domains 1 (LIMS1), autophagy-related 12 (ATG12), microtubule-associated protein 1 light chain 3 beta (MAP1LC3B), integrin subunit alpha-1 (ITGA1), mitogen-activated protein kinase 1 (MAPK1), glycogen synthase kinase 3β (GSK3β), and mitogen-activated protein kinase 8 (MAPK8).ConclusionCollectively, these data indicate repetitive HI exposure alters plasma sEV miRNA content, but not sEV size or number. Furthermore, for the first time we demonstrate that previously unknown miR-7844-5p targets mRNAs known to be involved in mitochondrial apoptosis, autophagy regulation, mood disorders, and neurodegenerative disease.