Integrierte Entwicklung von Automotive-Software mit AutoFocus

Zur Beherrschung der komplexen vernetzten und verteilten Funktionen von Automotive-Software ist eine Beschreibung des zu erstellenden Systems auf verschiedenen Abstraktionsebenen und schrittweise überg?nge zwischen diesen Ebenen notwendig. Neben der Definition geeigneter Ebenen werden zur Unterstützung echtzeitkritischer Systemanteile ein einheitliches Berechnungsmodell, ebenenspezifische Beschreibungstechniken, sowie methodische Regeln für diese Abstraktionsebenen eingeführt und in den Werkzeugprototypen AutoFocus integriert.     

Statistical analyses in the physiology of exercise and kinanthropometry

Research into the physiology of exercise and kinanthropometry is intended to improve our understanding of how the body responds and adapts to exercise. If such studies are to be meaningful, they have to be well designed and analysed. Advances in personal computing have made available statistical analyses that were previously the preserve of elaborate mainframe systems and have increased opportunities for investigation. However, the ease with which analyses can be performed can mask underlying philosophical and epistemological shortcomings. The aim of this review is to examine the use of four techniques that are especially relevant to physiological studies: (1) bivariate correlation and linear and non-linear regression, (2) multiple regression, (3) repeated-measures analysis of variance and (4) multi-level modelling. The importance of adhering to underlying statistical assumptions is emphasized and ways to accommodate violations of these assumptions are identified.     

Presenting Food Science Effectively

While the need to present food science information effectively is viewed as a critical competency for food scientists by the Institute of Food Technologists, most food scientists may not receive adequate training in this area. Effective presentations combine both scientific content and delivery mechanisms that demonstrate presenter enthusiasm for the topic and generate audience interest. This paper provides food science presentation “best practices” based upon the results of the author's 10 y of experience teaching communication skills to 1st‐year graduate students. Topics include development of a “Presentation Inventory” that encourages presenters to consider why they are presenting, who they are presenting to, what information they plan to present, and how they plan to present the information. More specific sections of the paper address presentation introductions and conclusions, developing visual aids, responding to audience questions, flow, pacing, and time management, technological competency, and tips on how to practice a presentation. Such information should be applicable to all types of food science practitioners including undergraduate and graduate students, postdoctoral scholars, teaching and research academics, and government, industrial, and consulting food scientists. An awareness of such “best practices” among presenters of food science information can help raise the bar to improve the quality of contemporary food science presentations.     

Modelling Molecular Mechanisms: A Framework of Scientific Reasoning to Construct Molecular-Level Explanations for Cellular Behaviour

Although molecular-level details are part of the upper-secondary biology curriculum in most countries, many studies report that students fail to connect molecular knowledge to phenomena at the level of cells, organs and organisms. Recent studies suggest that students lack a framework to reason about complex systems to make this connection. In this paper, we present a framework that could help students to reason back and forth between cells and molecules. It represents both the general type of explanation in molecular biology and the research strategies scientists use to find these explanations. We base this framework on recent work in the philosophy of science that characterizes explanations in molecular biology as mechanistic explanations. Mechanistic explanations describe a phenomenon in terms of the entities involved, the activities displayed and the way these entities and activities are organized. We conclude that to describe cellular phenomena scientists use entities and activities at multiple levels between cells and molecules. In molecular biological research, scientists use heuristics based on these intermediate levels to construct mechanistic explanations. They subdivide a cellular activity into hypothetical lower-level activities (top-down approaches) and they predict and test the organization of macromolecules into functional modules that play a role in higher-level activities (bottom-up approaches). We suggest including molecular mechanistic reasoning in biology education and we identify criteria for designing such education. Education using molecular mechanistic reasoning can build on common intuitive reasoning about mechanisms. The heuristics that scientists use can help students to apply this intuitive notion to the levels in between molecules and cells.     

Socialisation into organised sports of young adolescents with a lower socio-economic status

Studies investigating sport socialisation often focussed on the barriers for youngsters from lower socio-economic status (SES) families to participate in sport. In the present study, the socialisation into sports of young adolescents from lower SES families that do participate in organised sports was investigated. A total of 9 girls and 12 boys from lower SES families (18 Dutch; three foreign ethnic background) from one city in the Netherlands who participated in organised sport were interviewed. Although multiple agents may be of influence on the socialisation process, this study was limited to the family, school and peers as potential socialising contexts. Drawing on the theoretical work of Bourdieu and Bernstein, parents were found to be the main influencers of the sports habitus of these young adolescents. The school context appeared to have no influence on their sport socialisation. Peers were found to have an influence on the choice for a specific type of sport. This interplay between socialising contexts for young adolescents from lower SES families is similar to the sport socialisation of youngsters from higher SES families. Therefore, it is suggested that if sport socialisation takes place, then the role of SES is less pronounced than often assumed. Moreover, there seem to be differences in the relative importance of the socialising contexts with younger children with a lower SES. Therefore, it is hypothesised that the relative importance of socialising agents changes over time. Although the findings may be limited to the specific sample of this study, they provide hypotheses that challenge the often-presumed importance of SES if sport socialisation takes place.     

A physically active lifestyle is related to a lower level of skin autofluorescence in a large population with chronic-disease (LifeLines cohort)

Background:Physical activity(PA)has substantial health benefits and is important in combatting chronic diseases,which have been associated with elevated levels of advanced glycation endproducts(AGEs).AGEs play a role in the aging process,and an association between PA and AGEs has been reported.We aimed to investigate the relationship between PA and AGE accumulation in a general population and in a population with chronic diseases.Methods:This large cross-sectional population study used data from adult participants in the LifeLines project,with participant information drawn from the LifeLines database as well data from patients with diabetes mellitus or renal and/or cardiovascular diseases.Tissue AGE accumulation was assessed non-invasively by skin-autofluorescence(SAF)using an AGE reader(DiagnOptics Technologies BV,Groningen,the Netherlands).PA was assessed using the short questionnaire to assess health-enhancing physical activity(SQUASH).Multivariate linear regression analyses were adjusted for age,body mass index,sex,and smoking status.Results:Data from 63,452 participants(general population n=59,177,chronic disease n=4275)were analyzed.The general population was significantly younger(43.58±11.77 years,mean±SD)and had significantly lower SAF(1.90±0.42 arbitrary units(AU))compared to the population with chronic disease(age:55.51±12.07 years;SAF:2.27±0.51 AU).In the group with chronic disease,more hours of moderate to vigorous physical activities per week were associated with lower SAF(β=-0.002,95%confidence interval(95%CI):-0.002 to-0.001).For the general population,there was no association between hours of moderate to vigorous activity and SAF(β=3.2×10^-5,95%CI:0.000-0.001,p=0.742).However,there was an association in the general population between total hours of PA per week and SAF(β=4.2×10^-4,95%CI:0.000-0.001,p<0.001),but this association was not found in the chronic disease population(β=-3.2×10^-4,95%CI:-0.001 to 0.000,p=0.347).Conclusion:Our study demonstrates that an inverse relationship exists between PA and AGE accumulation in the population with chronic disease.More hours of moderate to vigorous activity is associated a significantly decreased SAF.More PA is associated a lower SAF,even after for the established predictors(age,body mass index,smoking status,and sex).Our findings could help to promote health and prolong longevity.     

The state steers by remote control: Standardising teacher education

This article questions whether the teacher training standards, (Department for Education and Employment Circular 4/98) have made it more difficult for teacher educators to help student teachers to become critically reflective teachers. It is suggested that, following the introduction of the discourse of the three 'e's', efficiency, economy and effectiveness and the teacher training standards, teacher 'education' has been transformed into teacher 'training' within an ideology of technical rationality. Four classroom-based episodes are introduced to form the contexts through which the teacher education standards are interrogated. It is argued that these standards ignore important issues to do with equality in the classroom and the relationship between education and the state. Ideas are suggested for teaching sessions using the episodes to encourage the development of a critically reflective perspective amongst student teachers.     

Intellectual Disability and Developmental Risk: Promoting Intervention to Improve Child and Family Well‐Being

Initial intervention processes for children with intellectual disabilities (IDs) largely focused on direct efforts to impact core cognitive and academic deficits associated with the diagnosis. Recent research on risk processes in families of children with ID, however, has influenced new developmental system approaches to early intervention. Recent risk and resilience processes are reviewed that connect stress, family process, and the high rates of behavioral problems in children with ID that have substantial influence on child and family outcomes. These models are linked to emerging evidence‐based intervention processes that focus on strategic parent skill training and mindfulness interventions that reduce parental stress and create indirect benefits for children's behavioral competencies. A family‐focused developmental systems approach (M. J. Guralnick, 2011) is emphasized.