More than Male-Gazing: Reflections on Female Fans of Rugby Union in New Zealand, 1870–1920

ABSTRACT

The presence of women in and around rugby union in New Zealand remains on the margins of the histories of the game of rugby and the more social and cultural histories that explore rugby’s impact on the formation of a New Zealand national identity. Yet, as this article demonstrates, women have long since engaged with rugby union in ways that may well have assisted in its ascendancy and ultimate claiming of the title of New Zealand’s national game. Through readings of newspapers, magazines, and club histories covering the period from the 1870s through to the Great War a picture emerges: women from both the middle and lower classes of New Zealand society supported the game of rugby as spectators, supporters, and fans. They did so in a manner that was sometimes acceptable but at other times regarded as distinctly inappropriate. In addition, women’s involvement was informal and localized – most obvious at the community level – and it is this feature that helps to explain women’s virtual invisibility in the histories of rugby union in New Zealand.     

Osmotically driven drug delivery through remote-controlled magnetic nanocomposite membranes

Implantable drug delivery systems can provide long-term reliability, controllability, and biocompatibility, and have been used in many applications, including cancer pain and non-malignant pain treatment. However, many of the available systems are limited to zero-order, inconsistent, or single burst event drug release. To address these limitations, we demonstrate prototypes of a remotely operated drug delivery device that offers controllability of drug release profiles, using osmotic pumping as a pressure source and magnetically triggered membranes as switchable on-demand valves. The membranes are made of either ethyl cellulose, or the proposed stronger cellulose acetate polymer, mixed with thermosensitive poly(N-isopropylacrylamide) hydrogel and superparamagnetic iron oxide particles. The prototype devices'' drug diffusion rates are on the order of 0.5–2 μg/h for higher release rate designs, and 12–40 ng/h for lower release rates, with maximum release ratios of 4.2 and 3.2, respectively. The devices exhibit increased drug delivery rates with higher osmotic pumping rates or with magnetically increased membrane porosity. Furthermore, by vapor deposition of a cyanoacrylate layer, a drastic reduction of the drug delivery rate from micrograms down to tens of nanograms per hour is achieved. By utilizing magnetic membranes as the valve-control mechanism, triggered remotely by means of induction heating, the demonstrated drug delivery devices benefit from having the power source external to the system, eliminating the need for a battery. These designs multiply the potential approaches towards increasing the on-demand controllability and customizability of drug delivery profiles in the expanding field of implantable drug delivery systems, with the future possibility of remotely controlling the pressure source.     

Core-shell hydrogel beads with extracellular matrix for tumor spheroid formation

Creating multicellular tumor spheroids is critical for characterizing anticancer treatments since they may provide a better model of the tumor than conventional monolayer culture. Moreover, tumor cell interaction with the extracellular matrix can determine cell organization and behavior. In this work, a microfluidic system was used to form cell-laden core-shell beads which incorporate elements of the extracellular matrix and support the formation of multicellular spheroids. The bead core (comprising a mixture of alginate, collagen, and reconstituted basement membrane, with gelation by temperature control) and shell (comprising alginate hydrogel, with gelation by ionic crosslinking) were simultaneously formed through flow focusing using a cooled flow path into the microfluidic chip. During droplet gelation, the alginate acts as a fast-gelling shell which aids in preventing droplet coalescence and in maintaining spherical droplet geometry during the slower gelation of the collagen and reconstituted basement membrane components as the beads warm up. After droplet gelation, the encapsulated MCF-7 cells proliferated to form uniform spheroids when the beads contained all three components: alginate, collagen, and reconstituted basement membrane. The dose-dependent response of the MCF-7 cell tumor spheroids to two anticancer drugs, docetaxel and tamoxifen, was compared to conventional monolayer culture.     

心的中心地位:道家之间的论战

心与身体其他感觉器官的关系问题,备受先秦两汉所有重要思想流派的争议。众所周知,传统儒家认为心是主"情"的器官,并具有分析其他感官之间差异的能力1。对于孟子来说,"四端"学说就是关于"心"的内容,最为显著的是恻隐之心,它能促进人们德性的成长2。对于儒家来说,与其他自然的感觉器官相比,"心"是较为高级的。因为它不仅具有思考的能力,而且能评估人们所遇之事;而其他感知器官,仅仅是在于接触其他事物3。"心"比其     

Library as a Partner in Co-Designing Learning Spaces: A Case Study at Tampere University of Technology,Finland

This article presents a case of co-designed temporary learning spaces at a Finnish academic library, together with the results of a user-survey. The experimental development of the multifunctional spaces offered an opportunity for the library to collaborate with its parent organisation thus broadening the role of the library. Hence, library can be seen as a third player facilitating learning spaces. Additionally, the library's own expertise was strengthened through successful cooperation with the undergraduate students and other actors. The results support prior research, where studying in the library is target-oriented differing from other learning spaces in providing support and resources.     

Imagining the Journalist of the Future: Technological Visions of Journalism Education and Newswork

Digitization has resulted in great uncertainty for journalism, leading to disruption of business models, revenue streams, media distinctions, and production practices. This uncertainty has led to many articles, reports, blog posts, and general commentary discussing the future of both journalism and the skills required by journalists to succeed in this environment. This essay analyzes these discourses, focusing specifically on the nature of technology as the sole determiner of journalism’s future, with interventions aimed at journalism education and the structure of newswork. An idealized notion of the technologically adept journalist, ready to usher in digital stability, emerges as the object of these debates and, thanks in large part to the limited scope and ahistorical character of digital discourse, obscures more persistent, systemic critiques of technology and journalism.     

Flipping the classroom to teach systematic reviews: the development of a continuing education course for librarians

Objective:The researchers used the flipped classroom model to develop and conduct a systematic review course for librarians.Setting:The research took place at an academic health sciences library.Method:A team of informationists developed and conducted a pilot course. Assessment informed changes to both course components; a second course addressed gaps in the pilot.Conclusion:The flipped classroom model can be successful in developing and implementing a course that is well rated by students.     

Systematic Dynamic Effects in Multiple Impact Pairs and Distributed Factors

In this paper in general the dynamic effects are considered and described, caused by different stand-ing waves in discrete and distributed systems with impacts and other strongly positional non-linear fac-tors, introduction of which in the models of me-chanical objects is dictated by the necessity to con-sider processes, accompanied with impacts of me-chanical subsystems of different nature.     

一类高阶中立型时滞微分方程的振动性

用不同于已有文献的方法研究了一类高阶中立型微分方程,本文不需要条件f∞t0Q(s)ds=∞,获得了这类方程振动性的几个新的结果.