Fluorescent probes: a new way to study lymphocyte activation

Fluorescent dyes can be used as cell probes which bind, according to their chemical structure, to particular subcellular regions of lymphocytes. Because of their sensitivity to variations in the local molecular environment, expressed by changes in fluorescence emission, they provide a means of studying the early events of lymphocyte activation to antigens and mitogens. The technology also yields a rapid assay of lymphocyte activation and thus new diagnostic tests of cell-mediated immunity, for example to organ transplants and to cancer.     

Using action research as a methodological tool: understanding teachers' understanding of science

A series of questions and answers between Jennifer Nias in her role as supervisor and Steve Waters-Adams as student explores the rationale for the inclusion of action research as a methodological tool within a wider PhD study. The study explored the effect of teachers' understanding of the nature of science on their teaching. In discussing the complexities of the research, Steve Waters-Adams suggests that action research provided a powerful means of gaining access to important tacit and dialectical aspects of teachers' practice. The discussion considers the process of action research, particularly with regard to the extent that its form and purpose may be defined, the importance of collaboration and the centrality of personal commitment. Steve Waters-Adams concludes that there is scope for subject-oriented research in education to make more use of action research as a methodological tool, given that the process engages with, and exposes for scrutiny, practitioners' values, aims and motives.     

Improving K-12 pedagogy via a Cloud designed for education

Cloud computing offers an opportunity to improve K-12 pedagogy with services tailored to teachers’ needs in individual classrooms. The Cloud can deliver services such as remote access to learning tools in a cost effective manner to school systems struggling with reductions in local and state funding. This article explores the distinct ways that a Cloud designed specifically for education can be applied to K-12 education's academic mission. It uses observations from a case study in North Carolina rural high schools using an educational Cloud called the Virtual Computing Lab to access dynamic geometry and algebra software.     

Multilevel Factors Affecting College Students’ Perceived Knowledge Transferability: From the Perspective of Self-Determination Theory

Promoting students’ ability to transfer or apply their knowledge and skills to real-life situations is critical in higher education. The current study was designed to test the likelihood that the constructs based on self-determination theory (SDT) framework help understand college students’ perceived knowledge transferability. A total of 3783 undergraduates from 301 classes participated in this study. The results of a series of multilevel modeling analyses indicated that (a) competence satisfaction and identification were the most salient factors influencing students’ perceived knowledge transferability; (b) the SDT-related variables together explained 64.2% of the between-student variance in perceived knowledge transferability; (c) after controlling for student-level covariates and SDT-related variables, 7.9% of the variance in perceived knowledge transferability was caused by between-class differences, and 19.6% of it could be explained by course fields and course levels. Our results, which provide evidence of multilevel factors influencing college students’ perceived knowledge transferability, have implications for promoting transfer in higher education.

     

Impact of childhood maltreatment on physical health-related quality of life in U.S. active duty military personnel and combat veterans

Previous studies have found an association between childhood maltreatment (CM) and health-related quality of life (HRQoL), and to a lesser extent have considered whether psychiatric symptoms may explain the relationship. This study aimed to further our understanding of the link between CM and HRQoL by testing whether posttraumatic stress disorder (PTSD) or depressive symptoms mediate the relationship between childhood maltreatment and physical HRQoL. Mediation models were examined in a sample of male Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) active duty and combat veterans (n = 249). PTSD and depressive symptoms mediated the relationship between CM and overall physical HRQoL, as well as participation in daily activities due to physical health, bodily pain, and social functioning. Mediation of the relationship between childhood maltreatment and physical and social functioning by depression and PTSD symptoms may lend support to neurobiological hypotheses that childhood maltreatment sensitizes the nervous system and after repeated trauma may lead to the development of psychiatric symptoms, which have a major impact on morbidity and mortality.     

Relational turbulence and perceptions of partner support during reintegration after military deployment

The transition from deployment to reintegration can be stressful for returning military personnel and at-home partners, and support plays a key role in their ability to transition effectively. We draw on relational turbulence theory to advance predictions about how parameters of the relationship between returning service members and at-home partners predict their perceptions of their partner’s support during the post-deployment transition. We surveyed 235 individuals (117 returning service members, 118 at-home partners) who had experienced the transition within the past 6 months. Findings consistent with the theory indicated that relational turbulence partially mediated the negative associations that relational uncertainty and interference from a partner shared with partner support. Partner uncertainty was a direct negative predictor of partner support as well. We consider how these results extend theory, research, and practice.     

Children's early child care and their mothers' later involvement with schools

Theory and policy highlight the role of child care in preparing children for the transition into school. Approaching this issue in a different way, this study investigated whether children's care experiences before this transition promoted their mothers' school involvement after it, with the hypothesized mechanism for this link being the cultivation of children's social and academic skills. Analyses of 1,352 children (1 month-6 years) and parents in the NICHD Study of Early Child Care and Youth Development revealed that mothers were more involved at their children's schools when children had prior histories of high-quality nonparental care. This pattern, which was fairly stable across levels of maternal education and employment, was mediated by children's academic skills and home environments.     

Medical diagnostic consultation concerning mental retardation: An analogue study of school psychologists' attitudes

Recent research of relevance to school psychologists suggests that the cause, or etiology, of mental retardation can be established by medical diagnosticians in approximately one‐half of cases. In the current study, 109 practicing school psychologists considered a hypothetical case of an elementary student with mental retardation and indicated their attitudes toward the use of medical consultation. School psychologists were randomly assigned to one of three experimental conditions defined by the amount of information about medical diagnostic consultations they received: (a) no information, (b) guidelines from the American Academy of Neurology (AAN) calling for medical consultation in cases of developmental delay, or (c) AAN guidelines plus a concise summary of research on etiology, prevention, and mental retardation. School psychologists with more than 10 years of experience evidenced a more favorable attitude toward medical diagnostic consultation when provided more information, whereas their less experienced colleagues demonstrated no such pattern. This finding, together with others derived from participants' responses, is discussed regarding school psychologists' practice and training. © 2010 Wiley Periodicals, Inc.