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Policy makers take initiatives to stimulate knowledge ecosystems in technology hotspots. It is implicitly assumed that these ecosystems will lead to value networks through which the participating companies can realize a competitive advantage. Value networks refer to business ecosystems where the value proposition is offered by a group of companies which are mutually complementary. The strategy literature suggests that business ecosystems lead to competitive advantages for each of the partners in the ecosystem. Based on a unique hand-collected database of 138 innovative start-ups in the region of Flanders, we analyze the knowledge and business ecosystem and the financial support network. We find that the knowledge ecosystem is well structured and concentrated around a number of central actors while the business ecosystem is almost non-existent at the local level. Further, we find that the financial support network is almost 100% publicly backed and fails to bridge the knowledge and business ecosystem. The implications for policy makers who tend to focus on the development of local ecosystems are discussed.  相似文献   
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While much prior research has focused upon how the Technology Transfer Offices (TTOs) and other contextual characteristics shape the level of university spinoffs (USO), there is little research on entrepreneurial potential among individual academics, and to the best of our knowledge, no comparative studies with other types of spinoffs exist to date. In this paper we focus on an important but neglected aspect of knowledge transfer from academic research involving the indirect flow to entrepreneurship by individuals with a university education background who become involved in new venture creation by means of corporate spinoffs (CSO) after gaining industrial experience, rather than leaving university employment to found a new venture as an academic spinoff. We argue that the commercial knowledge gained by industry experience is potentially more valuable for entrepreneurial performance compared to the academic knowledge gained by additional research experience at a university. This leads us to posit that the average performance of CSOs will be higher than comparable USOs, but the gains from founder‘s prior experiences will be relatively higher among USOs whose founders lack the corporate context. We investigate these propositions in a comparative study tracking the complete population of USOs and CSOs among the Swedish knowledge-intensive sectors between 1994 and 2002.  相似文献   
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This article draws attention to the possibilities of the ongoing philosophical discussion about cosmopolitan universal values in relation to the normative challenges in environmental and sustainability education (ESE). The purpose of this paper is to clarify the philosophical problems of addressing universally sustainable responsibilities and values in ESE. Our arguments draw inspiration from the work of three poststructuralist scholars: we explore how Butler develops her claim that universal assertion requires a cultural translation, how Mouffe exposes the political in universal claim and how Todd argues that education needs to introduce students to a political language that enables them to critically reflect on their own and other groups’ values and actions. In the concluding part, we suggest the following guidelines for rethinking ESE: unmasking the political dimension, re-politicising education, seeing beyond the relativist and objectivist divide and using passion as a moving force.  相似文献   
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Within the academic field of futures in education there has been concern that pupils’ negative and pessimistic future scenarios could be deleterious to their minds. Eckersley (Futures 31:73–90, 1999) argues that pessimism among young people can produce cynicism, mistrust, anger, apathy and an approach to life based on instant gratification. This article suggests that we need to discuss negative and pessimistic future visions in a more profound and complex way since these contain both hope and hopelessness. A pessimistic view of the future does not have to be negative in itself: it can also illustrate a critical awareness of contemporary social order. This article therefore aims to explore hope and hopelessness in young people’s dystopias about the future. Adopting dystopias may open up possibilities, whereas adopting disutopias will only lead one to believe that there are no alternatives to the current dominant model of global capitalism. Even a dystopia that predicts the end of the world as we know it might be the beginning of a world that we have not seen yet.  相似文献   
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Instructor-facilitated collegiate classroom discussion (IFCCD) is a highly valued yet undertheorized instructional practice. Research examining the structure of classroom interaction, scholarship advocating rationales for discussion-based pedagogy, and an investigation of a related interactive classroom communication practice provide an informative backdrop for this study. The data in the study were collected using action-implicative discourse analytic techniques throughout a semester in three classrooms at the same university. Reconstructing the three levels of the practice through grounded practical theory—the problem/dilemma level, the normative situated ideals level, and the talk/discourse techniques level—provides some insight into why in two of these cases of IFCCD, engaged and participatory discussion was accomplished. The shared dilemma of the practice is reconstructed as the problem of engagement in which both individual engagement with curricular content and shared engagement in co-creation of the discussion are valued. The dilemmatic nature of the practice is explored specifically in terms of traditional and nontraditional teacher talk and associated participation structures. Significant similarities and differences across the three cases are found and examined in the reconstructions of instructor situated ideals and third-turn facilitation techniques. Initial conclusions are incorporated in the discussion of discourse-based applications for practitioners interested in facilitating discussion in college classrooms.  相似文献   
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Effects of competition, exercise, and mental stress on secretory immunity   总被引:2,自引:0,他引:2  
It has been suggested that the psychological stress associated with competitive sports events may help to explain the increased susceptibility to respiratory infections due to reductions in secretory immunity. In the current study, we investigated the influence of competitive exercise and psychological stress on secretory immunoglobulin A (s-IgA). Salivary s-IgA and heart rate were measured in 62 healthy young recreationally active men at rest and, in a between-subjects design, following one of four 8-min tasks: mental arithmetic, cycling at workloads of 60 to 180 W (mean = 146 W), mental arithmetic while cycling, or competitive cycling. Mental arithmetic was associated with significant increases in s-IgA concentration (mean = 49 microg.min(-1)) and s-IgA secretion rate (mean = 25 microg.ml(-1)) compared with rest, while mental arithmetic combined with exercise was associated with a significant increase in s-IgA concentration only (mean = 124 microg.min(-1)). In contrast, competitive exercise and exercise alone did not influence s-IgA concentration or secretion rate. Heart rate increased modestly to mental arithmetic (mean = 7 beats.min(-1)) and substantially, and similarly, to the three exercise tasks (mean = 56(62 beats.min(-1)). The hypothesis that the psychological stress of competitive exercise contributes to increased susceptibility to infection via reductions in s-IgA requires further investigation.  相似文献   
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An easy method is introduced allowing fast polydimethylsiloxane (PDMS) replication of nanofluidic lab-on-chip devices using accurately fabricated molds featuring cross-sections down to 60 nm. A high quality master is obtained through proton beam writing and UV lithography. This master can be used more than 200 times to replicate nanofluidic devices capable of handling single DNA molecules. This method allows to fabricate nanofluidic devices through simple PDMS casting. The extensions of YOYO-1 stained bacteriophage T4 and λ−DNA inside these nanochannels have been investigated using fluorescence microscopy and follow the scaling prediction of a large, locally coiled polymer chain confined in nanochannels.  相似文献   
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